Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

MRCP Part 2 > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

Joints affected by Rheumatoid Arthritis

A

MCP and PIP (NOT DIP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Multicentric Reticulohistiocytosis Features

A

Affects DIP + Multiple nodules over hand +

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Polyarteritis Nodosa Clinical Features

A

Weight loss >5 kg or livedo reticularis or testicular pain/tenderness or diastolic BP >90 mmHg or hepatitis B virus +ve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Microscopic Polyangiitis Antibody

A

ANCA - pANCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Granulomatosis with Polyangiitis Antibody

A

ANCA - cANCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Systemic Sclerosis Antibody

A

Anti Scl70 and Ani Centromere Antibody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Medication not recommended for management of Systemic Sclerosis

A

Corticosteroids (Hypertension)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

DOC for Systemic Sclerosis associated renal diseases

A

ACE Inhibitors (Ramipril)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Cryoglobulinaemia

A

purpuric rash + Raynaud’s + Rheumatoid factor positive and low C4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Juvenile Idiopathic Arthritis (Stills Disease) Clinical Features

A

Adolescent with Anemia + Morning Stiffness + Rash + Pericarditis + Uveitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Adult Onset Stills Disease Clinical Features

A

Arthritis + fever (>39°C) + maculopapular rash + serositis + Hepatosplenomegaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Needle-shaped crystals, negatively birefringent

A

Gout

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Rhomboid-shaped crystals, positively birefringent

A

Pseudogout - Calcium pyrophosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Raynaud’s + GERD + Restrictive pattern of spirometry

A

Systemic sclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Fibromyalgia

A

widespread pain for > 3 months + Antibody and other blood tests negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Management of Gonococcal Arthritis

A

Ceftriaxone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Burning Micturition and Swollen Joints Diagnosis

A

Gonococcal Arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Features of Scleroderma renal crisis

A

malignant hypertension + Increased Creatinine + ‘onion skin’ intrarenal vasculature.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Gene Test Before starting Azathioprine

A

TPMT gene test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

eosinophilic granulomatosis with polyangiitis Management if unable to taper steroids

A

Steroid + azathioprine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

eosinophilic granulomatosis with polyangiitis clinical features

A

asthma + nephrotic syndrome + positive pANCA.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Annual Check-up for Systemic Sclerosis Patient

A

Echocardiogram + PFT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Confirmatory Test for Rheumatoid Arthritis

A

Anti CCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

DOC for Granulomatosis with polyangiitis to induce remission

A

IV methylprednisolone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Steroid Dosing of Giant Cell Arteritis

A

60 mg prednisolone per day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Association of Giant Cell Arteritis

A

Polymyalgia rheumatica.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Most common cause of optic neuropathy in Giant Cell Arteritis

A

anterior ischaemic optic neuropathy (AION)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

First Line Management for Osteoporosis

A

Bisphosphonates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Benefit of IV Zoledronic Acid for Osteoporosis

A

Needs to be administered once a year only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Osteoporosis with T score of -4.0 or more and fractures `

A

Teriparatide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Cancer patient with severe hypophosphatemia and glycosuria

A

Oncogenic Osteomalacia (Seen in CLL)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

First Line Management of Raynaud’s Phenomenon

A

Nifidipine or Losartan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Bechet Disease HLA

A

HLA-B51 and HLA-B5

34
Q

Bechets Diseases Ocular Manifestation

A

Bilateral Uveitis

35
Q

Knee Pain + RUQ discomfort + Suprapubic Tenderness Causative Organism

A

Neisseria Gonorrhoea - Gonococcal Arthritis

36
Q

Cancer which can increase risk of Osteogenic Sarcoma

A

Retinoblastoma

37
Q

Costochondritis management

A

Naproxen 250mg QDS

38
Q

Henoch Schonelein Purpura Clinical Features

A

Abdominal Pain + Joint Pain + Purpuric Rash in Legs + Microscopic Hematuria

39
Q

Hemochromatosis with B/L Joint Pain

A

Chondrocalcinosis

40
Q

Necrotizing Glomerulonephritis + Hemoptysis Diagnosis

A

Goodpasture syndrome

41
Q

Initial Management of Goodpasture syndrome

A

IV Methyl Prednisolone + Cyclophosphamide

42
Q

Mainstay Management of Goodpasture syndrome

A

Plasmapheresis

43
Q

Osteomalacia Diagnosis

A

Low serum calcium + Low serum phosphate + Increased ALP

44
Q

Strongest Environmental Risk Factor for RA

45
Q

IL12/23 - Inhibitor

A

ustekinumab

46
Q

Discoid Lupus Features

A

Scarring Alopecia + Photosensitive Rash + Plaques on face and Scalp

47
Q

Rash Around Eyes

A

Heliotrope Rash seen in Dermatomyositis

48
Q

Dermatomyositis antibody

A

Anti- Jo1 Antibody

49
Q

Anti Topoisomerase 1 Antibody Lung Finding

A

Interstitial Lung Diseases

50
Q

Anti Centromere Antibody Lung Finding

A

Pul Art HTN

51
Q

IL-6 Receptor Inhibitor

A

Tocilizumab

52
Q

Complication of Tocilizumab

A

Neutropenia

53
Q

Methotrexate Toxicity - Complication

A

Myelosuppression - Do CBC

54
Q

DEXA Cut off Values

A

-2.5 or less in Normal cases and -1.5 or less in patient on steroids

55
Q

Hepatomegaly + Proteinuria + Raised ALP

A

Amyloidosis

56
Q

Review of Patient with Pagets Disease

A

6monthly ALP

57
Q

APLA Syndrome Antibody test

A

Lupus Anticoagulant + Anti Cardiolipin antibody + Anti Beta 2 Glycoprotein 1

58
Q

Nose Bleeds+ Voice Hoarseness + Auricular Chondritis

A

Relapsing Polychondritis

59
Q

Contra- Indication for TNF Alpha Inhibitor Therapy

A

Multiple Sclerosis Patient

60
Q

Causative Organism for Osteomyelitis in Puncture Wound

A

Pseudomonas Aeruginosa

61
Q

Deformed Joint + No Pain Diagnosis

A

Charcot Joint

62
Q

Pain Over Greater Tuberosity + Painful arc on abduction

A

Supraspinatus Tendonitis

63
Q

Most common cause of Dermatomyositis

A

Malignancy - Do malignancy screening

64
Q

CTLA-4 Inhibitor

65
Q

Psoriatic Arthritis mangement

A

Methotrexate, Ciclosporine and Leflunomide

66
Q

Normal Straight Leg Raising test seen in

A

Lumbar Spinal Stenosis

67
Q

Tophacious Gout other place to present

A

Ear lobe!!!

68
Q

Ankle Synovitis + Hypercalcemia + Hilar Lymphadenopathy Diagnosis

A

Sarcoidosis

69
Q

X-ray finding in Osteomalacia

A

Low density bands extending into cortex (Looser’s Zone)

70
Q

Pauciarticular Stills Disease Lab Finding

71
Q

Treatment of Rheumatoid Arthritis with Active Synovitis

A

Methotrexate + Steroid

72
Q

Anti Hypertensive Medication Causing Raynauds Phenomenon

A

Methysergide and Atenolol

73
Q

Causes of Drug Induced Lupus

A

Thiazides, Phenytoin, Statin and Isoniazid

74
Q

Management of DVT in Bechets Syndrome

A

Prednisolone + Azathioprine

75
Q

Digital Ulcerations of Fingers and Toes + Heavy Smoking History

A

Buerger’s disease (Thromboangiitis obliterans)

76
Q

Gottron’s papules

A

Look the images!!!!!

77
Q

Timeline to Stop TNF-Alpha inhibitors prior to surgery

A

2-4 weeks prior

78
Q

Intermittent self resolving joint pain

A

Palindromic rheumatism - open access to rheumatology clinic

79
Q

Joint pain and swelling after loose stools

A

Reactive Arthritis - Campylobacter Infection

80
Q

Mainstay treatment of Dermatomyositis

A

High Dose Prednisolone

81
Q

Charcot Arthropathy Management

A

Immobilization in Plaster Cast

MRCP Part 2 (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions