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MRCP Part 2 > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

Joints affected by Rheumatoid Arthritis

A

MCP and PIP (NOT DIP)

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2
Q

Multicentric Reticulohistiocytosis Features

A

Affects DIP + Multiple nodules over hand +

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3
Q

Polyarteritis Nodosa Clinical Features

A

Weight loss >5 kg or livedo reticularis or testicular pain/tenderness or diastolic BP >90 mmHg or hepatitis B virus +ve

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4
Q

Microscopic Polyangiitis Antibody

A

ANCA - pANCA

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5
Q

Granulomatosis with Polyangiitis Antibody

A

ANCA - cANCA

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6
Q

Systemic Sclerosis Antibody

A

Anti Scl70 and Ani Centromere Antibody

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7
Q

Medication not recommended for management of Systemic Sclerosis

A

Corticosteroids (Hypertension)

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8
Q

DOC for Systemic Sclerosis associated renal diseases

A

ACE Inhibitors (Ramipril)

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9
Q

Cryoglobulinaemia

A

purpuric rash + Raynaud’s + Rheumatoid factor positive and low C4

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10
Q

Juvenile Idiopathic Arthritis (Stills Disease) Clinical Features

A

Adolescent with Anemia + Morning Stiffness + Rash + Pericarditis + Uveitis

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11
Q

Adult Onset Stills Disease Clinical Features

A

Arthritis + fever (>39°C) + maculopapular rash + serositis + Hepatosplenomegaly

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12
Q

Needle-shaped crystals, negatively birefringent

A

Gout

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13
Q

Rhomboid-shaped crystals, positively birefringent

A

Pseudogout - Calcium pyrophosphate

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14
Q

Raynaud’s + GERD + Restrictive pattern of spirometry

A

Systemic sclerosis

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15
Q

Fibromyalgia

A

widespread pain for > 3 months + Antibody and other blood tests negative

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16
Q

Management of Gonococcal Arthritis

A

Ceftriaxone

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17
Q

Burning Micturition and Swollen Joints Diagnosis

A

Gonococcal Arthritis

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18
Q

Features of Scleroderma renal crisis

A

malignant hypertension + Increased Creatinine + ‘onion skin’ intrarenal vasculature.

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19
Q

Gene Test Before starting Azathioprine

A

TPMT gene test

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20
Q

eosinophilic granulomatosis with polyangiitis Management if unable to taper steroids

A

Steroid + azathioprine

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21
Q

eosinophilic granulomatosis with polyangiitis clinical features

A

asthma + nephrotic syndrome + positive pANCA.

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22
Q

Annual Check-up for Systemic Sclerosis Patient

A

Echocardiogram + PFT

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23
Q

Confirmatory Test for Rheumatoid Arthritis

A

Anti CCP

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24
Q

DOC for Granulomatosis with polyangiitis to induce remission

A

IV methylprednisolone

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25
Steroid Dosing of Giant Cell Arteritis
60 mg prednisolone per day
26
Association of Giant Cell Arteritis
Polymyalgia rheumatica.
27
Most common cause of optic neuropathy in Giant Cell Arteritis
anterior ischaemic optic neuropathy (AION)
28
First Line Management for Osteoporosis
Bisphosphonates
29
Benefit of IV Zoledronic Acid for Osteoporosis
Needs to be administered once a year only
30
Osteoporosis with T score of -4.0 or more and fractures `
Teriparatide
31
Cancer patient with severe hypophosphatemia and glycosuria
Oncogenic Osteomalacia (Seen in CLL)
32
First Line Management of Raynaud's Phenomenon
Nifidipine or Losartan
33
Bechet Disease HLA
HLA-B51 and HLA-B5
34
Bechets Diseases Ocular Manifestation
Bilateral Uveitis
35
Knee Pain + RUQ discomfort + Suprapubic Tenderness Causative Organism
Neisseria Gonorrhoea - Gonococcal Arthritis
36
Cancer which can increase risk of Osteogenic Sarcoma
Retinoblastoma
37
Costochondritis management
Naproxen 250mg QDS
38
Henoch Schonelein Purpura Clinical Features
Abdominal Pain + Joint Pain + Purpuric Rash in Legs + Microscopic Hematuria
39
Hemochromatosis with B/L Joint Pain
Chondrocalcinosis
40
Necrotizing Glomerulonephritis + Hemoptysis Diagnosis
Goodpasture syndrome
41
Initial Management of Goodpasture syndrome
IV Methyl Prednisolone + Cyclophosphamide
42
Mainstay Management of Goodpasture syndrome
Plasmapheresis
43
Osteomalacia Diagnosis
Low serum calcium + Low serum phosphate + Increased ALP
44
Strongest Environmental Risk Factor for RA
Smoking
45
IL12/23 - Inhibitor
ustekinumab
46
Discoid Lupus Features
Scarring Alopecia + Photosensitive Rash + Plaques on face and Scalp
47
Rash Around Eyes
Heliotrope Rash seen in Dermatomyositis
48
Dermatomyositis antibody
Anti- Jo1 Antibody
49
Anti Topoisomerase 1 Antibody Lung Finding
Interstitial Lung Diseases
50
Anti Centromere Antibody Lung Finding
Pul Art HTN
51
IL-6 Receptor Inhibitor
Tocilizumab
52
Complication of Tocilizumab
Neutropenia
53
Methotrexate Toxicity - Complication
Myelosuppression - Do CBC
54
DEXA Cut off Values
-2.5 or less in Normal cases and -1.5 or less in patient on steroids
55
Hepatomegaly + Proteinuria + Raised ALP
Amyloidosis
56
Review of Patient with Pagets Disease
6monthly ALP
57
APLA Syndrome Antibody test
Lupus Anticoagulant + Anti Cardiolipin antibody + Anti Beta 2 Glycoprotein 1
58
Nose Bleeds+ Voice Hoarseness + Auricular Chondritis
Relapsing Polychondritis
59
Contra- Indication for TNF Alpha Inhibitor Therapy
Multiple Sclerosis Patient
60
Causative Organism for Osteomyelitis in Puncture Wound
Pseudomonas Aeruginosa
61
Deformed Joint + No Pain Diagnosis
Charcot Joint
62
Pain Over Greater Tuberosity + Painful arc on abduction
Supraspinatus Tendonitis
63
Most common cause of Dermatomyositis
Malignancy - Do malignancy screening
64
CTLA-4 Inhibitor
Abatacept
65
Psoriatic Arthritis mangement
Methotrexate, Ciclosporine and Leflunomide
66
Normal Straight Leg Raising test seen in
Lumbar Spinal Stenosis
67
Tophacious Gout other place to present
Ear lobe!!!
68
Ankle Synovitis + Hypercalcemia + Hilar Lymphadenopathy Diagnosis
Sarcoidosis
69
X-ray finding in Osteomalacia
Low density bands extending into cortex (Looser's Zone)
70
Pauciarticular Stills Disease Lab Finding
ANA +ve
71
Treatment of Rheumatoid Arthritis with Active Synovitis
Methotrexate + Steroid
72
Anti Hypertensive Medication Causing Raynauds Phenomenon
Methysergide and Atenolol
73
Causes of Drug Induced Lupus
Thiazides, Phenytoin, Statin and Isoniazid
74
Management of DVT in Bechets Syndrome
Prednisolone + Azathioprine
75
Digital Ulcerations of Fingers and Toes + Heavy Smoking History
Buerger's disease (Thromboangiitis obliterans)
76
Gottron's papules
Look the images!!!!!
77
Timeline to Stop TNF-Alpha inhibitors prior to surgery
2-4 weeks prior
78
Intermittent self resolving joint pain
Palindromic rheumatism - open access to rheumatology clinic
79
Joint pain and swelling after loose stools
Reactive Arthritis - Campylobacter Infection
80
Mainstay treatment of Dermatomyositis
High Dose Prednisolone
81
Charcot Arthropathy Management
Immobilization in Plaster Cast

MRCP Part 2 (11 decks)

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