Rheumatology Flashcards

1
Q

Anti-Ro antibodies

A

Primary Sjogren syndrome
May also be positive for ANA, RF and have high IgG with normal Kappa/Lambda

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2
Q

Polyarteritis nodosa affects..

A

Skin; purpura, ulcers
Renal, GN, haematuria
Lungs
Abdominal pain, PR bleeding
New hypertension
Fatigue
Polyneuropathy

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3
Q

Start someoneone on immunosuppressents but has a history of TB, what to do?

A

Monitor every 3 months for recurrance

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4
Q

Which cytokines are raised in RA?

A

TNF-a, IL 1, IL 6 and FGF

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5
Q

Eosinophilic granulomatosis with polyangiitis

A

Asthma
Eosinophilia >10%
Vasculitis neuropathy
Pulmonary infiltrates
Sinus disease
CXR may show pulmonary shadows

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6
Q

Granulomatosis with polyangiitis

A

Sinusitis/ saddle nose deformity
Pulmonary disease - cough, haemoptysis
Renal disase - haematuria, proteinuria

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7
Q

Granulomatosis with polyangiitis antibody

A

c-ANCA

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