Rheumatological markers Flashcards by Stephanie Harris

Q

Anti-dsDNA

A

SLE

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Q

Anti-Sm

A

SLE

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Q

Anti-histone

A

Drug-induced SLE

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Q

Anti-Ro

A

Sjogrens

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Q

Anti-scl70 (anti-topoisomerase 1)

A

Diffuse systemic sclerosis (scleroderma)

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Q

Anti-centromere

A

Limited systemic sclerosis (scleroderma)

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Q

Anti-SRP

A

myositis

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Q

Anti-RNA synthetases (mainly anti-Jo 1)

A

Anti-synthetase syndrome

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Q

Anti-u1-snRNP

A

Mixed connective tissue disease

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Q

pANCA (ANCA MPO)

A

Microscopic polyangiitis, polyarteritis nodosa (PAN)

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Q

cANCA (ANCA PR3)

A

Granulomatous polyangiitis (GPA/Wegner’s)

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Q

HLA B27

A

Seronegative spondyloarthropathies

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Q

HLA DQ2/8

A

Coeliac disease

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Q

HLA DR2

A

Anti-GBM (Goodpasture’s), MS

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Q

HLA DR3/4

A

T1DM (autoimmune diabetes)

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Q

HLA DR5

A

Hashimoto’s thyroiditis, pernicious anaemia

Q

HLA A3

A

Haemachromatosis

Q

HLA B8 & HLA DR3

A

Autoimmune Addison’s, MG, Sjogrens

Q

HLA B35

A

De Quervain’s thyroiditis (subacute thyroiditis)

Q

HLA B38

A

PsA

Q

HLA B51

A

Behcet’s disease

Q

HLA B47

A

21-hydroxylase deficiency

Q

HLA Cw6

A

Common psoriasis

Q

HLA DR3

A

Celiac sprue, dermatatitis herpetiformis, lupoid hepatitis

Q

HLA DR4

A

Pemphigus, RA