Renal buzzwords Flashcards
Effacement of foot processes + segmental sclerosis/hyalinosis +/- IgM deposits
FSGS
Rf: Hispanic, African-American, sickle cell disease, HIV
FSGS
Rf: caucasian middle-aged adults, malignancy
Membranous GN
Thickened GBM, “spike & dome” appearance on silver stain, granular immune complex deposits
Membranous GN
Crescentic, no staining on immunofluorescence
Pauci-immune (GPA/Wegners, EGPA/Churg-Strauss, microscopic polyangiitis)
Mesangial proliferation, IgA deposits in mesangium
IgA nephropathy
Kimmestiel-Wilson nodules
Diabetic nephropathy
Tram-tracking
MPGN
Starry-sky IgG deposits
Post-infective GN
Crescentic + linear “ribbon-like” IgG deposits
Anti-GBM/Goodpastures
+ Sinusitis
GPA/ Wegners
+ Pulmonary symptoms (Rf: younger pts)
Anti-GBM/ Goodpastures
RPGN
Pauci-immune, IgA, Anti-GBM/Goodpasture’s, SLE
“Hum-like” subepithelial deposits
Post-infective GN
Nephrotic symptoms
Hypercoagulability, hypoalbuminaemia, hyperlipidaemia, oedema, proteinuria (>3.5g/day)