Rheumatoid Arthritis Drugs

Question 1

Folate metabolism inhibitor; Non-biologic DMARD

Answer 1

Methotrexate

Question 2

Inhibits macrophages, maybe TLR9 in dendritic cells; Non-biologic DMARD

Answer 2

Hydroxychloroquine

Question 3

Pyrimidine synthesis inhibitor in T cells; Non-biologic DMARD

Answer 3

Leflunomide

Question 4

Inhibits COX & scavenges free radicals (antigen presenting cells & T cells); Non-biologic DMARD

Answer 4

Sulfsalazine

Question 5

Reduces macrophage phagocytosis and affects antigen presenting cells & T cells; Non-biologic DMARD

Answer 5

Gold

Question 6

Blocks DNA synthesis, primary site of action T cell; Non-biologic DMARD

Answer 6

Azathioprine

Question 7

Calcineurin inhibitor to inhibit T cell activation; Non-biologic DMARD

Answer 7

Cyclosporine

Question 8

Block TNF action; Biologic DMARD

Answer 8

Etanercept, Inflixumab

Question 9

Interleukin 1 receptor antagonist; Biologic DMARD

Answer 9

Ankinra

Question 10

Blocks T cell activation by antigen presenting cell (CD 80); Biologic DMARD

Answer 10

Abatacept

Question 11

Blocks B cell activation (CD 20); Biologic DMARD

Answer 11

Ritixumab

Question 12

Arthritis Treatments

Answer 12

1. NSAIDs
2. Corticosteroids
3. Non-biological disease modifying anti-rheumatic drugs (DMARDs)
4. Biologic (DMARDs)