Rheumatoid arthritis

Question 1

what type of antibody is usually rheumatoid factors

1. IgA
   2, IgG
2. IgM
3. IgE

Answer 1

3. IgM

Question 2

which antibody of the patient does rheumatoid factor react with

1. IgA
   2, IgG
2. IgM
3. IgE

Answer 2

2. IgG

Question 3

what 2 tests can be used to test for rheumatoid factor

1. rose waaler test
2. IgA antibody
3. ASCA antibody
4. latex agglutination

Answer 3

1. rose waaler test

4. latex agglutination

Question 4

which of the tests if less specific for investigation rheumatoid factor

1. rose waaler test
2. IgA antibody
3. ASCA antibody
4. latex agglutination

Answer 4

4. latex agglutination

Question 5

list 3 other conditions that may be associated with a + RF factor

Answer 5

Felty syndrome

sjorgens syndrome

infective
endocarditis

SLE

systemic sclerosis

Question 6

what is felty syndrome?

1. commonly complication of RA presence of 3 conditions: RA, splenomegaly and neutropenia
2. associated with dry mouth and eyes
3. infections of the endocardium
4. widespread fibrosis and vascualr abnormalities affecting skin, lungs, GI tract, heart and kidney

Answer 6

1. commonly complication of RA presence of 3 conditions: RA, splenomegaly and neutropenia

Question 7

what does NICE recommend when investigating RA with are rheumatoid factor negative

1. test for IgA antibody
2. test for anti CCP antibody
3. ASCA antibody

Answer 7

test for anti CCP antibody