RHEUMATOID ARTHRITIS Flashcards

1
Q

What is a pannus?

A

vascular connective tissue granulation
formed in the synovium
by proliferating fibroblasts

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2
Q

What does a pannus cause

A

Bone erosion

Produces enzymes that destroy nearby cartilage

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3
Q

What disease would you see rat bite erosions with?

A

RA

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4
Q

Where is RA frequently seen first radiographically?

A

Wrist

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5
Q

What are 3 distinctive locations of RA?

A

Distal radius
Distal ulna
carpus

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6
Q

What other disease aside from RA would you expect to see spotty carpal sign?

A

tuberculosus arthritis
gout
Sudeck’s atrophy

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7
Q

What are the 5 characteristics of RA in the carpus?

A
spotty carpal sign
midcarpal joint fusion
zigzag deformity
terry thomas sign (separation of scaphoid and lunate)
capute ulnae syndrome
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8
Q

How frequently is the foot the initial location?

A

15% of patients

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9
Q

Marginal erosions on the foot are seen where?

A

medial MT heads 1-4

5th- LATERAL

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10
Q

What is Lanois deformity?

A

digital fibular deformity, except 5th MTP

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11
Q

What is the most common cause for bilateral protrusia acetabuli?

A

Hip RA

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12
Q

What is protrusion acetabuli?

A

acetabulum displaced medially

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13
Q

Superior and medial hip dislocation may indicate______

where as axial displacement indicates____

A

DJD

RA

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14
Q

How common is fat pad sign in RA of the elbow?

A

90%

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15
Q

Uniform bicompartmental loss of joint space is seen in RA of what joint?

A

Knee

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16
Q

What is the most frequent systemic autoimmune inflammatory disease of children?

A

JRA

17
Q

what is the etiology of JRA?

A

unknown

18
Q

What is Still’s disease?

A

juvenille chronic arthritis- seronegative

19
Q

What disease is seropositive?

A

Adult- type RA

20
Q

What are the 3 forms of Still’s Disease?

A
Classic Systemic (20%)- anemia, pale, rash, mild radiographic changes
Polyarticular disease (50%)- bilateral pain, bird like features, females
Pauciarticular Monoarticular disease (30%)- large joints, most common females, most common knee
21
Q

Who is most affected and when by SLE?

A

females 2nd-4th decades

22
Q

How common is butterfly rash?

A

40%

23
Q

Are SLE deformities reversible?

A

yes

24
Q

What is the classic triad of Sjogren’s Syndrome and how many do you need?

A

keratoconjunctivitis
xerostomia
RA

2

25
Q

What is a disorder of striated muscle?

A

dermato and polymyositis

26
Q

What are the 5 criteria of derma to and polymositis

A
  1. proximal systemic muscle weakness that progresses weeks to months
  2. increased serum levels of muscle enzymes or increased level of urinary creatine
  3. abnomral electromyogram
  4. abnormal muscle biopsy
  5. presence of cutaneous disease