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Rheuma Flashcards

1
Q

RA + pulmo nodules

A

Caplans syndrome

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2
Q

Orange peel skin

A

Nephrogenic fibrosing dermopathy

Eosinophilic fasciitis

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3
Q

Fastest acting dmard

A

MTX

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4
Q

Dmard w/c decreases mortality in ra

A

Mtx

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5
Q

What to monitor w/ mtx tx?

A

Cbc, crea, alt q2-4wks x 3, q8-12wks x 3 then yearly

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6
Q

How to treat mtx induced renal failure

A

Glucarpidase

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7
Q

Predictor of cvs mortality in ra

A

Inc homocysteine

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8
Q

Tx for atlanto-odontoid subluxation

A

8mm asymptomatic- surgery

Symptomatic- surgery

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9
Q

Hydrochloroquine side effect

A

Macular degeneration

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10
Q

Felty’s syndrome

A

Leukopenia and splenomegaly

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11
Q

Still’s dse

A

Leukocytosis, fever, salmon colored rash

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12
Q

Sweet’s syndrome

A

Leukocytosis, painful red nodules

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13
Q

Tx of ankylosing spondylitis

A

Exercise, PT
If with pain, Nsaids
If unresponsive, anti-TNF alpha agents

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14
Q

How to follow up px with ankylosing spondylitis

A

Xray q3months

ESR for dse activity

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15
Q

Skin manifestation common in Reiter’s

A

Keratoderma blenorrhagica

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16
Q

Tx of psoriasis w/ skin and nail involvement

A

MTX

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17
Q

Never drugs in psoriasis

A

Hydroxychloroquine
Beta blocker
Sunlight (UVB)

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18
Q

Pathergy test positive

A

Behcet’s dse

Mouth/genital ulcers, EN, uveitis

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19
Q

Tx of mucocutaneous sx of behcet’s

A

Colchicine

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20
Q

Tx of moderate to severe behcet’s

A

Steroids

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21
Q

Caribbean with high fever and joint pains

A

Chikungunya

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22
Q

Positive titers for ana

A

> 1:160

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23
Q

Positive titers for rf

A

1:80

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24
Q

Diff bet Oa and Ra erosions

A

OA: central erosions
RA: periarticular erosions

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25
Q

Double line sign in T2 MRI

A

Avascular necrosis

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26
Q

Pain on lat aspect of hip, cant sleep on that side

A

Trochanteric bursitis

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27
Q

Negatively birefringent crystals

A

Gout

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28
Q

Positively birefringent crystals

A

Pseudogout

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29
Q

Tx of gout with CI to NSAIDs or colchicine

A

Steroids

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30
Q

Allopurinol increases level of

A

Azathioprine

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31
Q

In pseudogout, what is the crystal involved

A

ca pyrophosphate

32
Q

Most commonly affected joint in pseudogout

33
Q

Variable bifringence

A

Ca oxalate

34
Q

Pain on abduction, tenderness on bicipital groove

A

Bicipital tendinitis

35
Q

Pain on abd beyond 40 deg and int rot

A

Rotator cuff tendinopathy

36
Q

Drop arm test +

A

Rotator cuff tear

37
Q

No pain on extremes of movement but px complains of pain on abd

A

Subacromial bursitis

38
Q

Pain beyond abduction to 120 deg

A

Acromioclavicular joint arthritis

39
Q

Shoulder pain with recurrent swelling; tap reveals rbcs, ca phosphate and hydroxyapatite crystals

A

Milwaukee shoulder

40
Q

What to do if there is thenar muscle wasting in carpal tunnel

A

NCV studies

41
Q

Sat night palsy

A

Compression of radial nerve in spiral groove

42
Q

Tx for dupuytren’s contracture

A

Collagenase injections

43
Q

Pain in the anatomical snuff box after fall

A

Scaphoid fracture

Spica splint then do mri or bone scan

44
Q

Meralgia paresthetica

A

Compression of femoral cutaneous nerve

45
Q

Pain on medial aspect of knee 5cm below joint line

A

Pes anserine bursitis

46
Q

Tenderness in the lateral aspect of the knee above joint line, snap on flexion

A

Iliotibial band syndrome

47
Q

Movie goers sign

A

Chondromalacia patella/ patellofemoral syndrome

48
Q

Point tenderness just below the knee while extending knee against resistance

A

Osgood schlatter’s syndrome

49
Q

Ant drawer sign and lachman test +

50
Q

Mcmurray sign +

A

Meniscal tear

51
Q

Valgus test +

52
Q

Pain on percussion posterior and inferior to medial malleolus

A

Tarsal tunnel syndrome

53
Q

Tx for fibromyalgia

A

Amitriptyline

54
Q

Tx for polymyalgia rheumatica

55
Q

Recurrent pain in the neck, xray shows calcification of ligaments in neck

A

Crown dens syndrome

56
Q

Sle

A

Anti dsDNA, anti smith

57
Q

Drug induced lupus

A

Anti-histone

58
Q

Subacute cutaneous lupus

A

Anti-Ro (ssa)

59
Q

Scleroderma

A

Anti-scl 70

Anti-topoisomerase

60
Q

Crest

A

Anti-centromere

61
Q

MCTD

62
Q

Polymyositis

63
Q

Dermatomyositis

64
Q

Which sign is specific for dermatomyositis

A

Gottron’s papules

65
Q

Sjogren’s

A

Anti-ro, anti-la

66
Q

Schirmer test positive result

67
Q

Wegener’s

A

P anca (myeloperoxidase)

68
Q

Vacuoles + inflammation

A

Inclusion body myositis

69
Q

Vacuoles with no inflammation

A

Colchicine myopathy

70
Q

Poor prognosis for dermatomyositis

71
Q

Steroid psychosis

A

Greater than pred 20mg/d with auditory hallucinations

72
Q

Sle psychosis

A

On steroids

73
Q

What marker to follow for sle dse progression

A

Anti-dsdna

74
Q

Tx for wegeners

A

Non-severe: steroid + mycophenolate
Severe: steroid + cyclophosphamide
In remission: MTX
In relapse: rituximab

75
Q

Appears like ICH but BP normal

A

Amyloid angiopathy of the brain

76
Q

Recurrent Serositis + arthritis

A

Familial mediterranean fever

77
Q

Tx for Familial mediterranean fever

A

Colchicine

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