Rheum Popcorn 2 Flashcards

1
Q

Who gets osteoporosis most commonly?

A

Postmenopausal white women

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2
Q

How is fx risk determined in osteoporosis?

A

FRAX tool

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3
Q

Risk factors for what?

  • Previous low trauma fx
  • Chronic Glucocorticoids
  • RA
A

Osteoporosis fracture risk

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4
Q

Gold standard for dx of osteoporosis?

A

Duel-energy x-ray absorptiometry (DEXA) scan

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5
Q

What T-score is diagnostic for oosteoporosis

A

< -2.5

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6
Q

What is the best non-pharmacologic tx for osteoporosis

A

Exercise

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7
Q

1st line tx for osteoporosis?

A

Vit D and calcium

Bisphosphonates

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8
Q

Biphosphonates are contraindicated in what condition

A

CKD

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9
Q

Black box warning for biphosphonates?

A

ONJ

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10
Q

T/F: sex hormone replacement is appropriate therapy for osteoporosis?

A

FALSE

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11
Q

What is the MC complication of Osteoporosis? How do you monitor?

A

Vertebral fx

Monitor for height loss

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12
Q

Dx of what condition:

  • Chronic wide spread pain for >6wks
  • All 4 quadrants of the body
  • 11/18 tender points
A

Fibromyalgia

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13
Q

What is the only treatment option for Fibromyalgia that has evidence for helping with FM pain?

A

Exercise

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14
Q

Tx for Fibromyalgia?

A

Exercise

Amitryptyline

(NO OPIOIDS)

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15
Q

Systemic findings

+

Lung and kidney findings`

A

Vasculitis syndromes, AKA Vasculitides

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16
Q

Which condition is MC in F>50y/o and is assoc. w/ Giant cell arteritis

A

Polymyalgia Rheumatica

(large vessel disorder)

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17
Q

Stiffness/aching in neck, shoulder and pelvic girdle but NO weakness

A

Polymyalgia Rheumatica

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18
Q

How you you dx Polymyalgia Rheumatica?

A

Clinical

19
Q

How do you tx Polymyalgia Rheumatica?

A

Low dose Prednisone

(should respond w/in 72 hrs)

20
Q

Polymyalgia Rheumatica:

  • NO muscle weakness like ______ and _____
  • Does NOT cause blindness like ______
  • Responds to low dose prednisone, where _____ requires high dose
A
  • NO muscle weakness like Polymyositis and Polyarteritis nodosa
  • Does NOT cause blindness like Temporal Arteritis
  • Responds to low dose prednisone, where TA requires high dose
21
Q

Necrotizing inflammation of med and sm arteries w/o GN

NO lung involvement

A

Polyarteritis Nodosa

22
Q

MC organ affected in Polyarteritis Nodosa?

A

Skin

(Livedo reticularis, subcutaneous nodules, skin ulcers, distal gangrene)

23
Q

What is the preferred dx of Polyarteritis Nodosa?

A

Tissue bx of involved organ

24
Q

Is polyarteritis Nodosa ANCA pos or neg?

A

Neg

25
Q

How do you tx Polyarteritis Nodosa?

A

High dose Corticosteroids

26
Q

Which dz?

  • Boys <5y/o
  • Strawberry tongue
  • Severe diaper rash
  • F >5d
A

Kawasaki Dz

27
Q

What are pts w/ Kawasaki Disease at high risk for

A

Coronary Aneurysm

28
Q

How do you tx Kawasaki Disease

A

High dose ASA

IVIG

29
Q

Triad of what condition?

  • Upper resp
  • Lower resp
  • Kidney (glomerular nephritis)
A

Granulomatosis w/ Polyangitis

30
Q

What imaging is preferred in Granulomatosis w/ Polyangitis?

A

CT

31
Q

The following is commonly seen in what condition

  • Nasal cong
  • OM
  • Sinusitis
  • Mastoiditis
  • Gingivitis
  • Stridor

(MIld, benign Resp sxs that don’t get better w/ tx)

A

Granulomatosis w/ Polyangitis

32
Q

How do you tx Granulomatosis w/ Polyangitis?

A

Cyclophosphamide + Corticosteroids

OR

Rituximab + Corticosteroids

33
Q

What is the MC associated condition w/ Eosinophilic Granulomatosis?

A

Asthma

34
Q

What is the gold standard for Dx of Eosinophilic Granulomatosis w/ Polyangitis

A

Lung Biopsy

35
Q

How do you tx Eosinophilic Granulomatosis w/ Polyangitis

A

Systemic Glucocorticoids

36
Q

What is the MC systemic vasculitis in children?

A

IgA Vasculitis (“Henoch Schoenlein Purpura)

37
Q
  • Acute onset fever
  • Palpable purpura on LE and buttocks
A

IgA Vasculitis

38
Q

What is the tetrad for IgA Vasculitis? (A GAP)

A
  • Purpura
  • Arthritis
  • Glomerulonephritis
  • Abdominal pain
39
Q

“Big 3” of Which condition:

  • LE purpura
  • Arthritis in knees and ankles
  • Hematuria
A

IgA Vasculitis

40
Q

What is the prognosis and tx of IgA vasculitis

A

Self-limiting

Tx: supportive, analgesics, low-dose steroids

41
Q

Which condition is MC in 20-40y/o Mediterraneans

A

Behcet’s Syndrome

42
Q

Recurrent, painful mucocutaneous ulcers of mouth and genitals

A

Behcet’s Syndrome

43
Q

Pathergy phenomenon is associated with which syndrome?

A

Behcet’s syndrome

44
Q

1st line tx for Behcet’s Disease

A

Prednisone