Rheum Popcorn 2 Flashcards

1
Q

Who gets osteoporosis most commonly?

A

Postmenopausal white women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How is fx risk determined in osteoporosis?

A

FRAX tool

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Risk factors for what?

  • Previous low trauma fx
  • Chronic Glucocorticoids
  • RA
A

Osteoporosis fracture risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Gold standard for dx of osteoporosis?

A

Duel-energy x-ray absorptiometry (DEXA) scan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What T-score is diagnostic for oosteoporosis

A

< -2.5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the best non-pharmacologic tx for osteoporosis

A

Exercise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

1st line tx for osteoporosis?

A

Vit D and calcium

Bisphosphonates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Biphosphonates are contraindicated in what condition

A

CKD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Black box warning for biphosphonates?

A

ONJ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T/F: sex hormone replacement is appropriate therapy for osteoporosis?

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the MC complication of Osteoporosis? How do you monitor?

A

Vertebral fx

Monitor for height loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dx of what condition:

  • Chronic wide spread pain for >6wks
  • All 4 quadrants of the body
  • 11/18 tender points
A

Fibromyalgia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the only treatment option for Fibromyalgia that has evidence for helping with FM pain?

A

Exercise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tx for Fibromyalgia?

A

Exercise

Amitryptyline

(NO OPIOIDS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Systemic findings

+

Lung and kidney findings`

A

Vasculitis syndromes, AKA Vasculitides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which condition is MC in F>50y/o and is assoc. w/ Giant cell arteritis

A

Polymyalgia Rheumatica

(large vessel disorder)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Stiffness/aching in neck, shoulder and pelvic girdle but NO weakness

A

Polymyalgia Rheumatica

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How you you dx Polymyalgia Rheumatica?

19
Q

How do you tx Polymyalgia Rheumatica?

A

Low dose Prednisone

(should respond w/in 72 hrs)

20
Q

Polymyalgia Rheumatica:

  • NO muscle weakness like ______ and _____
  • Does NOT cause blindness like ______
  • Responds to low dose prednisone, where _____ requires high dose
A
  • NO muscle weakness like Polymyositis and Polyarteritis nodosa
  • Does NOT cause blindness like Temporal Arteritis
  • Responds to low dose prednisone, where TA requires high dose
21
Q

Necrotizing inflammation of med and sm arteries w/o GN

NO lung involvement

A

Polyarteritis Nodosa

22
Q

MC organ affected in Polyarteritis Nodosa?

A

Skin

(Livedo reticularis, subcutaneous nodules, skin ulcers, distal gangrene)

23
Q

What is the preferred dx of Polyarteritis Nodosa?

A

Tissue bx of involved organ

24
Q

Is polyarteritis Nodosa ANCA pos or neg?

25
How do you tx Polyarteritis Nodosa?
High dose Corticosteroids
26
Which dz? * Boys \<5y/o * **Strawberry tongue** * Severe diaper rash * F \>5d
Kawasaki Dz
27
What are pts w/ Kawasaki Disease at high risk for
Coronary Aneurysm
28
How do you tx Kawasaki Disease
High dose ASA IVIG
29
Triad of what condition? * Upper resp * Lower resp * Kidney (glomerular nephritis)
Granulomatosis w/ Polyangitis
30
What imaging is preferred in Granulomatosis w/ Polyangitis?
CT
31
The following is commonly seen in what condition * Nasal cong * OM * Sinusitis * **Mastoiditis** * **Gingivitis** * Stridor (MIld, benign Resp sxs that don't get better w/ tx)
Granulomatosis w/ Polyangitis
32
How do you tx Granulomatosis w/ Polyangitis?
Cyclophosphamide + Corticosteroids OR Rituximab + Corticosteroids
33
What is the MC associated condition w/ Eosinophilic Granulomatosis?
Asthma
34
What is the gold standard for Dx of Eosinophilic Granulomatosis w/ Polyangitis
Lung Biopsy
35
How do you tx Eosinophilic Granulomatosis w/ Polyangitis
Systemic Glucocorticoids
36
What is the MC systemic vasculitis in children?
IgA Vasculitis ("Henoch Schoenlein Purpura)
37
* Acute onset fever * **Palpable purpura on LE and buttocks**
IgA Vasculitis
38
What is the tetrad for IgA Vasculitis? (A GAP)
* Purpura * Arthritis * Glomerulonephritis * Abdominal pain
39
"Big 3" of Which condition: * LE **purpura** * **Arthritis** in knees and ankles * **Hematuria**
IgA Vasculitis
40
What is the prognosis and tx of IgA vasculitis
**Self-limiting** Tx: supportive, analgesics, **low-dose steroids**
41
Which condition is MC in **20-40y/o Mediterraneans**
Behcet's Syndrome
42
Recurrent, painful mucocutaneous ulcers of mouth and genitals
Behcet's Syndrome
43
Pathergy phenomenon is associated with which syndrome?
Behcet's syndrome
44
1st line tx for Behcet's Disease
Prednisone