Rheum Exam 5 Flashcards
What dose the RAPID 3 score contain?
a. subjective sx
b. subjective sx and objective findings
c. objective findings
d. all of the above
subjective sx
What is included in DAS 28?
a. subjective sx
b. objective sx
c. ESR +PGA and 28 joints assessed for swelling and tenderness
d. all of the above
all of the above
What are used to asess disease progression?
Rapid 3
DAS 28
SDAI
CDAI
What is the disease activity monitoring tool for ankylosing spondylitis?
a. rapid 3
b. DAS 28
c. BASDAI
d. SDAI
BASDAI
What is the disease activity monitoring tool for SLE?
a. rapid 3
b. DAS 28
c. BASDAI
d. none of the above
none of the above
Which of the following are true of psoriatic arthritis?
a. RF is always negative in individuals with PsA
b. Onset occurs simultaneously with psoriasis of the skin
c. The peak symptom onset is 30-55 years of age
d. Affects females and males equally
c. The peak symptom onset is 30-55 years of age
d. Affects females and males equally
Which HLA is associated with psoriatic arthritis (though not as strongly as with other spondyloarthropathies)?
a. HLA-DR4
b. HLA-B27
c. HLA-DR2
d. HLA-DQ
HLA-B27
Stress is considered a risk factor for developing psoriatic arthritis.
Select one:
True
False
T
Peripheral joint involvement in PsA is more common in
a. Females
b. Males
F
Axial involvement of PsA is more common in
a. Males
b. Females
m
Which patterns are generally seen in PsA?
a. Morning stiffness lasting greater than 30 minutes
b. Joint pain worse with activity and better with immobility
c. Morning stiffness lasting less than 30 minutes
d. Joint pain worse with immobility and better with activity
Joint pain worse with immobility and better with activity
Morning stiffness lasting greater than 30 minutes
Which is the most predominant subgroup of PsA?
a. Polyarthritis
b. Asymmetrical oligoarthritis
c. Distal interphalangeal joint disease
d. Arthritis mutilans
e. Spondylitis
Asymmetrical oligoarthritis
“Sausage digit” occurs in about 50% of patients with psoriatic arthritis, What is the medical term for this symptom?
a. Dactylitis
b. Tenosynovitis
c. Kielbasa digit
d. Sclerodactyly
Dactylitis
Approximately, which percentage of patients with PsA develop arthritis mutilans?
a. 25%
b. 1%
c. 5%
d. 15%
5%
Enthesitis is defined as inflammation at the site of the insertion of tendons, ligaments and synovium into bone. Which tendon is most commonly affected in PsA?
a. Biceps tendon
b. Achilles tendon
c. Patellar tendon
d. Extensor hallucis longus tendon
Achilles tendon
Which should be included in the workup for psoriatic arthritis?
a. Deep tendon reflexes (DRTs)
b. Eye exam
c. Depression screening
d. Musculoskeletal exam
e. Skin and nail exam
b. Eye exam
c. Depression screening
d. Musculoskeletal exam
e. Skin and nail exam
Which differential diagnoses should be considered in the workup for PsA?
a. Hemochromatosis
b. Osteoarthritis
c. Trauma
d. Ankylosing spondylitis
e. Rheumatoid arthritis
Hemochromatosis
Ankylosing spondylitis
Rheumatoid arthritis
How is septic arthritis ruled out?
a. Physical exam
b. ESR/CRP
c. History alone
d. Joint aspiration and culture
Joint aspiration and culture
Individuals with PsA are at higher risk for cardiovascular disease
Select one:
True
False
T
Pencil-in-cup findings on imaging may be observed in which pathologies?
a. Osteoarthritis
b. Reactive Arthritis
c. Psoriatic arthritis
d. Rheumatoid arthritis
Psoriatic arthritis
Rheumatoid arthritis
Which joints are most commonly affected by pencil-in-cup deformity?
a. DIPs
b. Hips
c. PIPs
DIPs
Which osseous change observed on imaging is specific to PsA?
a. Cloudy opacity
b. Swan neck deformity
c. Subcortical cysts
d. Ivory phalynx
Ivory phalynx
What is the first-line pharmaceutical therapy for mild peripheral PsA arthritis?
a. Biologic DMARDs (TNF inhibitors)
b. Synthetic DMARDs (Methotrexate)
c. NSAIDs
d. Vitamin D
NSAIDs
What is the standard of care for severe psoriatic arthritis?
a. NSAIDs
b. Synthetic DMARDs (Methotrexate)
c. Biologic DMARDs (TNF inhibitors)
d. Vitamin D
Biologic DMARDs (TNF inhibitors)
What is the primary initial pharmaceutical intervention for axial psoriatic arthritis?
a. Biologic DMARDs (TNF inhibitors)
b. Synthetic DMARDS (methotrexate)
c. Intra Articular steroid injections
d. NSAIDs
NSAIDs
What daily dose of curcumin has been shown to improve symptoms of RA (and potentially PsA?
a. 1000mg
b. 300mg
c. 10g
d. 100mg
1000mg
Celiac disease is more prevalent in individuals with PsA
Select one:
True
False
T
Individuals with psoriasis and PsA should avoid even mild amounts of UV radiation and sun exposure
Select one:
True
False
F
Which vitamin deficiency has been noted in psoriasis and PsA patients?
a. Vitamin C
b. Vitamin D
c. B12
d. Vitamin E
Vitamin D
How often should a patient with active psoriatic arthritis or whos treatment is being adjusted be reassessed?
a. Every 6 months
b. Annually
c. Every 3 months
d. At least every month
Every 3 months
How often should a patient with stable psoriatic arthritis be reassessed?
a. Every 6 months
b. Every 3 months
c. Annually
d. At least once a month
Every 6 months
This remedy is indicated for sprains with boggy swelling.
a. Carbo animalis
b. Rhus tox
c. Ledum
d. Colchicum
ledum
80% of sarcoidosis cases present within this age range.
a. 15-20
b. >50
c. 45-60
d. 20-50
20-50
About half the individuals in whom sarcoidosis is identified are asymptomatic.
Select one:
True
False
T
In sarcoidosis, remission generally occurs
a. In black individuals more often than in white individuals
b. if there are no extra thoracic manifestations
c. Within the first two years of diagnosis
d. In individuals who are younger at diagnosis
Within the first two years of diagnosis
The most common systems involved in sarcoidosis include
a. Heart and lungs
b. Lymphatics and GI
c. Lungs and lymphatics
d. Lungs and GI
Lungs and lymphatics
Select the environmental exposures linked to increased risk of developing sarcoidosis.
a. Zirconium
b. Lithium
c. Zinc
d. Lead
e. Beryllium
f. Mercury
g. Aluminum
Aluminum
Beryllium
Zirconium
Mycobacterium tuberculosis is histologically similar to sarcoidosis with the major difference being that the granuloma in tuberculosis is _ whereas in sarcoidosis it is _
a. Caseating; non-caseating
b. Non-caseating; caseating
Caseating; non-caseating
The center of a sarcoid granuloma is filled with
a. Dead epithelial cells
b. bacteria
c. specialized macrophages called epithelioid cells
d. mast cells
specialized macrophages called epithelioid cells
Interstitial lung disease is defined as
a. A disorder resulting in airflow obstruction and reduction
b. As acute, inflammatory reaction in the lungs
c. A disorder causing fibrosis or scarring of the lugs
d. A disease only occurring in the interstitium of the lungs
A disorder causing fibrosis or scarring of the lungs
Which of the following is associated with chronic sarcoidosis and therefore likely to require systemic treatments?
a. Lupus pernio
b. Papular sarcoidosis
c. Plaque-like lesions
Lupus pernio
It is imperative to recommend patients with sarcoidosis to follow up with an ophthalmologist annually because
a. they are at increased risk of developing anterior uveitis leading to blindness
b. development of keratoconjunctivitis sicca is associated with higher mortality
c. They’re more likely to develop Sjogren’s syndrome, leading to dry eyes
d. They may develop glaucoma leading to impaired vision
they are at increased risk of developing anterior uveitis leading to blindness
Cardiovascular manifestations of sarcoidosis are
a. only addressed in someone with chest pain
b. rare and easily treated
c. Common in older individuals
d. Uncommon and serious
Uncommon and serious
In individuals with sarcoidosis, hilar involvement with lymphadenopathy is seen in _________ % of cases.
a. 90
b. 60
c. 30
d. 5
90
What helps differentiate the MSK symptoms of RA from sarcoidosis?
a. The radial deviation of RA is correctable but with sarcoidosis it is not
b. RA polyarthritis in symmetrical; sarcoidosis is asymmetrical
c. The ulnar deviation in correctable by patients with sarcoidosis but not by those with RA
d. RA will present with ulnar deviation; sarcoidosis presents with radial deviation
The ulnar deviation in correctable by patients with sarcoidosis but not by those with RA
Choose the symptom cluster described by Lofgren syndrome.
a. Uveitis + papular sarcoidosis + fever + lymphadenopathy
b. Erythema nodosum + polyarthritis + fatigue + glossitis
c. Erythema nodosum + hilar adenopathy + migratory polyarthralgia + fever
d. Hilar adenopathy + heart failure + erythema nodosum + glossitis
Erythema nodosum + hilar adenopathy + migratory polyarthralgia + fever
This is the most common presenting symptom in individuals with sarcoidosis.
a. fatigue
b. Polyarthralgia
c. Hilar adenopathy
d. fever
fatigue
Which bloodwork is likely to come back elevated in sarcoidosis patients.
a. RBC count
b. ESR and CRP
c. Eosinophils
d. Liver enzymes
ESR and CRP
A diagnosis of sarcoidosis requires this in the absence of lofgren syndrome
a. Fatigue as a clinical symptom
b. Migratory polyarthralgia
c. An X-ray demonstrating hilar adenopathy
d. A biopsy detecting noncaseating granulomas
A biopsy detecting noncaseating granulomas
For which stages of sarcoidosis is prednisone recommended?
a. Stages 3 and 4
b. Stages 2 and 3
c. Stages 1 and 2
d. Stages 0 and 1
Stages 3 and 4
Which dose of melatonin has been shown to resolve dyspnea and skin lesions in sarcoidosis patients in whom glucocorticoids have failed?
a. 10 mg/day
b. 1 mg/day
c. 5 mg/day
d. 20 mg/day
20 mg/day