RH Typing Flashcards
The Rh system was** first recognized** in a case report of:
a. hemolytic transfusion reaction.
b. Hemolytic disease of the fetus and newborn.
c. Circulatory overload.
d. Autoimmune hemolytic anemia.
A. hemolytic transfusion reaction.
What antigen is found in 85% of the white population and is always significant for transfusion purposes?
a. d
b. c
c. D
d. E
c. D
How are weaker-than-expected reactions with anti-D typing reagents categorized?
a. Rhmod
b. Weak D
c. DAT positive
d. Dw
b. Weak D
Cells carrying a weak-D antigen require the use of what test to demonstrate its presence?
a. Indirect antiglobulin test
b. Direct antiglobulin test
c. Microplate test
d. Warm autoadsorption test
a. Indirect antiglobulin test
b. Direct antiglobulin test
c. Microplate test
d. Warm autoadsorption test
How are Rh antigens inherited?
a. Autosomal recessive alleles
b. Sex-linked genes
c. Codominant alleles
d. X-linked
c. Codominant alleles
- Biochemically speaking, what type of molecules are Rh antigens?
a. Glycophorins
b. Simple sugars
c. Proteins
d. Lipids
c. Proteins
- Rh antibodies react best at what temperature (°C)?
a. 22
b. 18
c. 15
d. 37
d. 37
Rh antibodies are primarily of which immunoglobulin
class?
a. IgA
b. IgM
c. IgG
d. IgD
c. IgG
What do Rhnull cells lack?
a. Lewis antigens
b. Normal oxygen-carrying capacity
c. Rh antigens
d. MNSs antigens
c. Rh antigens
What antigen system is closely associated phenotypically
with Rh?
a. McCoy
b. Lutheran
c. Duffy
d. LW
d. LW
Anti-LW will not react with which of the following?
a. Rh-positive RBCs
b. Rh-negative RBCs
c. Rhnull RBCs
d. Rh:33 RBCs
c. Rhnull RBCs
Which of the following most commonly causes an individual to type RhD positive yet possess anti-D?
a. Genetic weak D
b. Partial D
c. C in trans to RHD
d. D epitopes on RhCE protein
b. Partial D
Which of the following is the most common Rh phenotype in African Americans?
a. Dce/dce
b. DcE/dce
c. DCe/dce
d. Dce/dCe
a. Dce/dce
