Revision Flashcards
A 56-year-old man is having a spinal anaesthetic for a lower limb operation
as he has been told he is not fit enough for a general anaesthetic.
Which would be the most appropriate local anaesthetic agent?
A. Bupivacaine alone
B. Lidocaine
C. Lidocaine/prilocine mixture
D. Lidocaine with adrenaline
E. Prilocaine
A – Bupivacaine alone
Bupivacaine is a longer-acting anaesthetic that can be used without
adrenaline for spinal or epidural anaesthesia. Bupivacaine can also be
injected into surgical wounds with adrenaline to reduce post-operative
pain for up to 20 hours.
when does pancreatic pseudocyst form?
4weeks after acute pancreatitis
A 33-year-old man is brought into the emergency department following
an assault with a baseball bat. He has bruising over the abdomen and
right loin and complains of abdominal pain. On examination, his chest is
clear with good air entry but his abdomen is rigid. On arrival, his heart
rate is 140/min and blood pressure 90/60 mmHg. He is given O-negative
blood in the resuscitation room but his observations remain unchanged.
What would be the next step in his management?
A. Diagnostic peritoneal lavage
B. Laparotomy
C. Urgent CT scan
D. Urgent intravenous urogram
E. Urgent ultrasound scan
B – Laparotomy
This patient has suffered blunt abdominal trauma and is haemodynami-
cally unstable despite blood resuscitation. This is an indication for an
urgent laparotomy, to identify and manage the site of bleeding. From the
history there are no obvious sites of blood loss, so it can only be assumed
that it is being lost into the abdomen.
What is boerhaave syndrome?
Boerhaave syndrome describes spontaneous transmural rupture of the
oesophagus, often associated with forceful vomiting.
common site : left posteolateral wall of the lower third of the oesoph-
agus.
SX (Mackler’s triad:) vomiting, lower thoracic pain subcutaneous emphysema -common abdominal pain -chest pain -SOB.
How many types of jaundice ?
3 types
- pre hepatic
- hepatic
- post hepatic
what will you see in pre hepatic jaundice?
inability of the liver to handle an excess amount of bilirubin being produced; Associated with -hereditary sphero- cytosis - Gilbert syndrome
INV
- serum bilirubin +
- urine bilirubin +
- conjugated bilirubin (normal)
- unconjugated bilirubin +/-
- AST/ALT = normal
- ALP = normal
- Gamma GT- normal
- urine color= normal
- stool color = normal
What will you see in hepatic jaundice ?
caused by a primary failure of the hepatocytes to metabolise or excrete bilirubin;
Associated:
- viral hepatitis
-liver metastasis
INV
- -serum bilirubin +
- urine bilirubin +/-
- conjugated bilirubin (normal or low)
- unconjugated bilirubin (normal or reduce)
- AST/ALT = ++
- ALP =+/-
- Gamma GT- ++
- urine color= normal / dark
- stool color = normal
What will you see in post-hepatic jaundice?
caused by the obstruction of bile ducts. Associated -gallstone -carcinoma on head of pancrease
INV
- serum bilirubin +
- urine bilirubin +
- conjugated bilirubin +
- unconjugated bilirubin (normal)
- AST/ALT = normal/ +
- ALP = ++
- Gamma GT- normal/ +
- urine color= dark
- stool color =pale
A 37-year-old woman presents to the GP with a 3-week history of frequent,
loose motions. She is very tired and complains of muscle weakness. A subsequent colonoscopy demonstrates a 1.5 cm sessile growth that has
multiple projections. The remainder of the colon was unremarkable.
What is the most likely diagnosis?
A. Adenomatous polyp
B. Colorectal carcinoma
C. Infective colitis
D. Pseudomembranous colitis
E. Villous adenoma
E – Villous adenoma
Villous adenomas are large polyps which look like sea anemones. Villous
adenomas secrete mucus and potassium, hence they can present with
diarrhoea and features of hypokalaemia (muscle weakness, myalgia and
arrhythmias). Of all the rectal polyps, the villous adenoma has the high-
est potential for malignant change, so it must be removed.
What is the ASA grading system ?
Grade I = normal, healthy individual (0.05% anaesthetic mortality)
Grade II = mild systemic disease that does not limit activity (0.4%
mortality)
Grade III = severe systemic disease that limits activity but is not incapacitating
(4.5% mortality)
Grade IV = incapacitating systemic disease that is constantly life-threatening
(25% mortality)
Grade V = moribund, not expected to survive over 24 hours with or
without surgery (50% mortality)
A mother brings her 5-week-old son to the paediatric outpatient clinic.
She is concerned as he has been having episodes of forceful vomiting after
feeds for the last 2 weeks. She says her son always seems hungry and now
is beginning to appear lethargic. Examination of the child reveals mild
dehydration and the presence of a smooth, firm, non-tender mass in the
right upper quadrant of the abdomen. Blood tests are sent.
What biochemical abnormalities would you expect to find?
A. Hyperchloraemic, respiratory alkalosis
B. Hypernatraemic, hyperkalaemic, metabolic alkalosis
C. Hypochloraemic, hyperkalaemic, metabolic alkalosis
D. Hypochloraemic, hypokalaemic, metabolic alkalosis
E. Hyponatraemic, metabolic acidosis
D – Hypochloraemic, hypokalaemic, metabolic alkalosis
A 53-year-old man presents to the GP with a deep, painful ulcer over the
big toe. He gives a 3-month history of severe calf pain on walking which is
only eased on resting. Examination shows cool peripheries with reduced
distal pulses.
Which ulcer does the patient most likely have?
A. Arterial ulcer
B. Curling ulcer
C. Marjolin ulcer
D. Neuropathic ulcer
E. Venous ulcer
A – Arterial ulcer
Arterial ulcers are typically painful, deep, well demarcated and occur
on the heels, toes and over bony prominences
A 45-year-old man has walked into the emergency department follow-
ing his involvement in a road traffic collision. On arrival at the hospital
he is anxious, but otherwise fine. Later, he suddenly becomes faint. He is taken into the resuscitation room where he is found to have a heart rateof 46/min and a blood pressure of 80/48 mmHg. Primary examination is
unremarkable and the patient has warm peripheries.
Which of the following is the most likely cause of his symptoms?
A. Cardiogenic shock
B. Haemorrhagic shock
C. Hypovolaemic shock
D. Neurogenic shock
E. Spinal shock
D – Neurogenic shock
Neurogenic shock is caused by sudden disruption or injury to the sympathetic
nervous pathways, resulting in the loss of vasomotor tone and
pooling of blood in the peripheries. This leads to profound hypotension.
modified Glasgow criteria for pancreas ?
Mnemonic PANCREAS P =p02 < 8kPa A= age >55 yr N= neutrophil WCC >15x10 C= calcium =<2.0mmol/l R= urea >16 mmol/l E= enzyme (AST, LDH > 600mmol/l) A= albumin <32mmol/l S-sugar >19mmol/l
Severe disease is present if three or more of the criteria are present
within 48 hours.
A 50-year-old woman with known gallstones presents to the emergency
department with severe epigastric pain radiating to the back together
with nausea and vomiting. Examination reveals localized epigastric peri-
tonitis and investigations reveal an amylase of 650 μ/L.
Which of the following would indicate a poor prognosis in this condition? A. Amylase of 650 μ/L B. Arterial pO2 of 7.0 kPa C. Patient age of 50 years D. Pyrexia of 38.5°C E. White cell count of 10 × 103 /μL
B – Arterial pO2 of 7.0 kPa
Malunion of supracondylar fractures = ?
cubitus varus deformity (‘gunstock deformity’).
What will you see in volkmann ischaemic contracture ?
a flexion
contracture of the hand and wrist, caused by circulatory compromise
and ischaemia leading to fibrosis of the forearm compartment. It
is a recognized complication of supracondylar fractures, 2nd in compartment syndrome
Treatment of
Volkmann ischaemic contracture involves surgery to release the contracted
muscles.
A 6-year-old boy who had a fracture above the left elbow and was treated
in a plaster cast is brought into the GP practice by his mother a few days
after plaster removal. She is worried due to the abnormal positioning of
his forearm. On examination, his left forearm appears to be shortened
and held in flexion at the wrist and the fingers.
Which of the following complications has led to this appearance?
A. Brachial artery injury
B. Lack of physiotherapy
C. Malunion at fracture site
D. Median nerve injury
E. Ulnar nerve injury
A – Brachial artery injury
This boy has presented with Volkmann ischaemic contracture, a flexion
contracture of the hand and wrist, caused by circulatory compromise
and ischaemia leading to fibrosis of the forearm compartment
A 40-year-old man presents to the GP complaining of increasing diffi-
culty in swallowing over the last few months. He tells you he has been
working in Mexico for the last two years with a new business. He is other-
wise well and denies any other symptoms.
Which of the following is the most likely cause of his symptoms? A. Chagas disease B. Gastro-oesophageal reflux disease C. Myasthenia gravis D. Plummer-Vinson syndrome E. Zenker diverticulum
A – Chagas disease
Chagas disease is a parasitic disease of the tropics caused by the protozoan
Trypanosoma cruzi
A 30-year-old woman presents with multiple bilateral breast swell-
ings which cause her discomfort, particularly just before her periods.
They have been present for several years but appear to be getting worse. What is the most likely diagnosis? A. Duct ectasia B. Fat necrosis C. Fibroadenoma D. Fibrocystic disease E. Peau d’orange
D – Fibrocystic disease
Fibrocystic disease of the breast is a common benign condition affecting
more than half of women, commonly between the ages of 30 and 50.
You are called to see a 56-year-old man who is one day post appendicec-
tomy because he became acutely short of breath. He has just been given his
first dose of cyclizine to relieve nausea. On arrival, the patient is breath-
less with the following observations: heart rate 122/min, blood pressure
86/48 mmHg and saturations 85% in air. Which of the following would you administer first? A. Adrenaline B. Chlorphenamine C. Fluids D. Hydrocortisone E. Salbutamol
A – Adrenaline
This patient is in anaphylactic shock, an acute life-threatening emergency
which can rapidly cause death if untreated.
A 43-year-old man presents to the GP with a 2-month history of wors-
ening headaches. The headaches are almost constant and are worse in
the morning. On examination, his skin is thick and greasy and he is
hypertensive.
A 43-year-old man presents to the GP with a 2-month history of wors-
ening headaches. The headaches are almost constant and are worse in
the morning. On examination, his skin is thick and greasy and he is
hypertensive.
A – Acromegaly
The headache is characteristic of an intracranial space-occupying lesion.
This, along with the features of greasy skin and hypertension, suggests acromegaly as the most likely cause from the given list. Acromegaly is caused
by a growth hormone-secreting tumour of the anterior pituitary gland. The
functions of growth hormone include lipolysis, protein synthesis and gluconeogenesis
– in other words it is anabolic. Patients with acromegaly may present
with headaches, excessive sweating, thick/oily skin, hypertrophy of soft
tissues (large nose/lips/tongue, ‘spade-like’ hands), big viscera, prognathism
(protruding lower jaw) and prominent supraorbital ridges.
A 55-year-old man presents to the emergency department with increasing
itching and upper abdominal discomfort. His wife has noticed that he is
looking ‘yellow’. On examination, there is a non-tender mass in the right
upper quadrant. The patient has a history of ulcerative colitis, which is
currently in remission.
What is the most likely diagnosis?
A. Cholangiocarcinoma
B. Gallstones
C. Haemolysis
D. Hepatitis
E. Pancreatic carcinoma
A – Cholangiocarcinoma
Cholangiocarcinoma is an adenocarcinoma of the biliary tree and is
associated with ulcerative colitis, primary sclerosing cholangitis and to a
lesser extent Crohn disease. It usually presents between the ages of 50 and
70 poor prognosis with an average survival of 6 months
A 27-year-old man presents to the emergency department after being
stabbed in the back. He is now unable to move his right leg. On exami-
nation, you note that he cannot feel pain on the left leg, although motor
function in this limb is preserved. What is the most likely diagnosis? A. Anterior cord syndrome B. Brown-Séquard syndrome C. Central cord syndrome D. Posterior cord syndrome E. Syringomyelia
B – Brown-Séquard syndrome
Brown-Séquard syndrome describes the features of unilateral transection
(hemisection) of the spinal cord