rEVISION Flashcards
CD4+ Th2 effector cells:
Cause B cell proliferation.
CD4 Th1 cells activate macrophage. Both types of CD4 are MHC Class II restricted.
Widely spread throughout the skin
Langerhans cell.
Located in the stratum spinosum part of the epidermis, these Langerhans cells are APCs.
What do natural killer cells release?
They release cytoplasmic granules called perforin and granzyme that cause target cell apoptosis.
Where can you find An area of high B cell concentration
Follicle of a lymph node.
The antigen-specific repertoire of lymphocytes is modified by somatic mutations during immune stimulation of which cell type?
Activated B cells in germinal centres
Macrophages:
Are capable of ingesting and killing pathogens
Selectins are important in:
Lymphocyte homing to tissues
What name is given to cellular receptors that bind antibodies?
Fc receptors
What is the principal function of the immune system?
Defence against microbial infections
Regarding cytokines:
Cytokine production is required for the induction of an acute phase response
What are named using the CD system of nomenclature?
Cell surface molecules present on a wide variety of cells
Secretory IgA:
Is important for mucosal immunity
CD8+ effector cells:
Kill their targets by inducing apoptosis
CD8+ effector cells:
Kill their targets by inducing apoptosis
Natural killer (NK) cell Has a role in the rejection of tumours, sensing loss of MHC class I expression
They release cytoplasmic granules called perforin and granzyme that cause target cell apoptosis.
