Review Questions - Cell Injury 2

Question 1

Upper GI endoscopy is performed on a 43-yo male who has complained of heartburn for several years. The biopsy demonstrates the presence of columnar epithelium with goblet cells. These findings indicate:
A. Dysplasia,
B. Hyperplasia,
C. Carcinoma,
D. Ischemia,
E. Metaplasia

Answer 1

E. Metaplasia

More than likely the diagnosis would be Barrett Esophagus.

Question 2

A 59-yo female had loss of consciousness that persisted for over an hour. She could not speak or move her right arm or leg following the episode. A cerebral angiogram revealed occlusion to her left middle cerebral artery. The following year a CT scan showed a large 5 cm cystic area in her left parietal lobe cortex. The CT demonstrates a lesion that is a consequence of resolution from which of the following events:
A. Atrophy,
B. Coagulation necrosis,
C. Apoptosis,
D. Caseous necrosis,
E. Liquefactive necrosis

Answer 2

E. Liquefactive necrosis

Question 3

The left lobe of an adult donor liver is used for orthotopic transplant in a recipient relative with severe liver disease. A year later, the size of each liver (donor and recipient) is greater than at the time of transplant. Which of the following cellular mechanisms accounts for this observation?
A. Metaplasia,
B. Dysplasia,
C. Hypertrophy,
D. Hyperplasia,
E. Anaplasia

Answer 3

D. Hyperplasia