Review Deck 98-184 Flashcards
Definition of glaucoma?
Group of diseases w progressive
- optic nerve damage
- visual field loss
2 categories of glaucoma?
Open angle glaucoma
- most common
Angle-closure glaucoma
Difference between open angle and closed angle glaucoma?
Open angle glaucoma
- blockage of aqueous outflow
Angle closure glaucoma
- structurally normal outflow pathway
Risk factors for open-angle glaucoma?
Increased age AA Family hx DM Systemic HTN
AAO risk factor weighting?
Charty thing that calculates the level of glaucoma risk
See slide 100
Clinical tests for open-angle claucoma?
IOP (may be normal)
Pupillary examination (crescent shadow)
Opthalmoscopy (cup-disk >0.6)
If you suspect POAG?
Ophthalmology referral
Treatment approach for lowering IOP?
Decreasing production of aqueous fluid
- B-blocker
- a2- agonist
- carbonic anhydrase inhibitors
Increasing outflow of aqueous
- less-selective sympathomimetics
- prostaglandins analogs
- miotic agents
Open angle glaucom meds
Chart slide 103
B adrenergic blocker side effects?
Decreased CO
Bronchoconstriction (NO COPD/asthma)
Alpha 2 adrenergic agonist SE?
Allergic conjunctivitis
Contact dermatitis
Less-selective sympathomimetics SE?
Exacerbation of hypertension
Prostaglandin analogs SE?
Conjunctival hyperemia
Who gets surgery for open angle?
If the optic neropathy worsens
Younger ps
Noncompliant pts
What is a trabeculoplasty?
Therapy using
- Argon laser
- Selective laser
What is a trabeculectomy?
Implant/shunt surgery
Aqueous fluid flows into subconjunctival space (filling bleb)
What is ciliary body ablation?
Destroys a portion of the ciliary epithelium
Symptoms of acute angle glaucoma?
Blurred vision (unilateral) Monocular halos Eye pain/photophobia Frontal HA Vasovagal symptoms N/V
Signs of acute angle closure glaucoma?
Mid-dilated pupil Conjunctival injection Lid edema Corneal edema w blurring of light reflex Elevated IOP (60-80mmHg)
What are the risk factors for acute angle-closure glaucoma?
Women 4x more 55-70 yrs Short, small, far-sighted eyes Extreme dilation Drugs - anticholinergics - sympathomimetics
Treatment of choice for acute angle-closure glaucoma?
Laser iridotomy (post attack)
Meds for acute angle closure glaucoma?
Timolol (aqueous fluid)
Acetazolamide IV
Isosorbide IV
Mannitol IV
Chronic angle-closure glaucoma signs and symptoms?
Asymptomatic (usually) Decreased vision/field loss Elevated IOP Broad bands of PAS Optic nerve damage
Normal Pupil
How are broad band PAS diagnosed?
With a gonioscopy
Surgical Tx for chronic angle-closure glaucoma?
Surgical - goniosynechialysis — strip the PAS - iridotomy — allow drainage
PAS = Peripheral anterior synechiae (PAS) are adhesions of the peripheral iris to the structures in the angle of the anterior chamber.
Medical Tx for congenital glaucoma?
Topical levobunolol or timolol
Oral acetazolamide
Surgical treatment for congenital glaucoma?
Goiniotomy (trabecular meshwork)
Trabeculotomy
Trabeculectomy
What is the medical tx used for with congenital glaucoma?
Its temporary measure to hold them until they can get surgery
We dont want kids to have to use drops for their entire life
S/s of neovascular glaucoma?
Asymptomatic (sometimes) Pain Red eye Photophobia Decreased vision
Treatment for neovascular glaucoma?
Timolol
Glaucoma filtration
Surgery
Steroids and glaucoma?
Prolonged use of steroids can cause reduction of outflow facility of trabecular meshwork
What types of steroids cause steroid response glaucoma?
High-dose skin creams
Inhalers
Treatment for steroid response glaucoma?
DC steroid
Decrease steroid dose
Add anti-glaucoma therapy
There are lots of types of glaucoma (technically its anything that plugs up the flow in the eye)
What other types are there?
Inflammatory open-angle glaucoma
Exfoliative glaucoma
Phacolytic glaucoma
Postoperative glaucoma
LTG or normal tension glaucoma
Diagnosis of glaucoma requires?
Progressive optic nerve damage
Progressive visual field loss
Without progressive optic nerve damage and visual field loss the pt just has?
Ocular hypertension
What is hemianopia?
Loss of an entire half of the visual field
What is hymonymous hemianopia?
Visual field loss on the same side in both eyes
What isis ipsilateral hemianopa?
Visual field loss is on the same side the lesion is on
What is contralateral hemianopia/?
Visual field loss on the opposite side of the lesion
What is scotoma?
An area of reduced or absent vision within an otherwise intact visual field
What is anisocoria?
Unequal size of the pupils >1mm
Visual field pathway?
Slides 117 and 118, prob worth a look
What is the afferent pathway?
CNII
Light travels up CNII, divides in the chiasm
Arrive at pretectal nucleus cross end and EW nuclei
What is the efferent pathway?
CN III
Signal sent from EW nuclei down the oculomotor nerve (CNIII)
The pupils constrict
If i tell you that the visual pathway has double decussation you are smart and know that this means …?
It first decussates t the chiasm
Second is at the prectal nuclei to the endinger-westphal nuclei
What is responsible for the direct/consensual response?
The double decussation
How does neurosyphilis present?
Its damage to the cenral pupil pathway so it causes
Argyll Robertson pupil
Argyle robertsons pupil is aka?
Describe it
Prostitue’s pupil
The pupil is small
Responds slowly/not at all to light
But Response to near accommodation
I.e. it accommodates but doesnt react
Contrasted with argyle robertson’s pupil adie’s tonic pupil is?
Idiopathic and benign
Signs of adie’s tonic pupil?
Dilated pupil
Reacts poorly to light
Reacts better to accomidation
Its “sluggish and tonic”
Who gets adie’s pupil?
Women
What non optho sign is seen with adie’s pupil?
Loss of DTR’s
Adie’s pupil does not have?
Abnormal extra-ocular movements
Ptosis
This are signs of CN III palsy
Causes of adies tonic pupil?
Idiopathic
Viral etiology
Inflammatory process
How to confirm adie’s pupil?
Give 0.125 pilocarpine
Adie’s pupils will constrict
Normal will not constrict
What causes horner’s syndrome (30,000’)
Injury to the sympathetic nerves of the face
Sings of horner’s syndrome?
Ptosis Pupillary miosis (constricted) Facial anhydrosis (lack of sweating)
What are some common causes of horner’s?
Stroke of brainstem Injury to carotid artery Tumor in lung Cluster HA Congenital
Diagnosis of horner’s?
10% cocaine
- dilates normal pupil
- no dilation in horner’s
Horner doesnt do cocaine
What happens during the swinging flashlight test if the pt has marcus gunn pupil?
When light is shone in the affected eye the pupils dilate bc the brain never receives the signal
Papilledema must be?
Bilateral
Causes of papilledema?
Intracranial mass
Impediment of CSF flow
Idiopathic intracranial hypertension
Symptoms of papilledema?
HA N/V Transient vision loss Pulsatile tinnitus Horizontal diplopia
Secondary to intracranial mass