Review Flashcards
SPECT scan
extent of brain damage post stroke
PET scan
parkinson’s, epilepsy, mental illness, heart attack
laproscopy
abdomen & pelvis
What two things effect metabolism of a pharmaceutical
age, immunity
Pregnancy Categories A- B C D E
A- no risk B- no risk in humans C- indeterminate risk, benefits may outweigh risk D- high risk, benefits may outweigh risk E- contraindicated
Controlled Substance Schedule I II III IV V
I- high abuse, no medical necessity
II- high abuse and dependency (opoids, amphetamines)
III- low abuse may cause dependence (steroids, analgesics, barbiturates, antidiarreal)
IV- low abuse, limited dependence (benzos)
V- low abuse, limited dependence (antitussive, anti diarrheal)
Anthelmintic
kills parasites and their eggs
anticholinergic
blocks parasympathetic nerve impulses
Antidepressants (tricyclic, MAOI, SSRI, SNRI)
end in -ine
- fluoxetine (prozac)
- sertaline (zoloft)
Common Anticoagulants
aspirin, heparin, warfarin (coumadin)
Ma huang shouldn’t use used with MAOI because…
it intensifies the effect of medication and side effects (stomachache, headache, tremors, hypertension)
Ren shen shouldn’t be used with antihyperglycemics, asprin, corticosteroids, digoxin, estrogen, MAOIs, opoids, warfarin
Increases hypoglycemia, increases bleeding, increases adverse effects of anti inflammatories, increases digoxin levels, intensify adverse effects of estrogen, can cause headaches, tremors, and manic episodes (MAOIs), reduces the effects of opoids, and increases bleeding
Green Tea (lu cha) should be avoided with which medication
warfarin- increases thromboembolism
Gan cao should be avoided with digoxin and diuretics because
with digoxin it decreases K+, and increases digoxin toxicity
- with diuretics it increases K+, wasting effects and interferes with effectiveness
St Johns Wort should be avoided with digoxin, iron supplements, MAOIs, OCPs, protease inhibitors, SSRIs, Tricyclic antidepressants, and warfarin
Digoxin- increases toxicity
iron- reduces iron absorption
MAOIs- augments maois, can cause traumatic hypertension
OCPs- increases metabolism of drugs, reduces effectiveness
Protease inhibitors- reduces blood level and efficacy
SSRIs- augments effects of drugs
Tricyclics- augments effects
Warfarin- increases risk of thromboembolism
Food-drug interactions- grapefruit
inhibits or slows metabolism of drugs
Food-drug interactions- tyramine
can cause hypertensive crisis if taking MAOI
Food-drug interactions- black tea
inhibits iron absorption
Food-drug interactions- alcohol
impairs thiamin, niacin, pyridoxin
Drug-mineral interactions: opoids, anticholinergics
decreases GI motility, constipation
Drug-mineral interactions: diuretics (thiazides, corticosteroids)
depletes K+ (can lead to arrhythmia)
Drug-mineral interactions: cortisol, aldosterone
increases sodium and water retention
Drug-mineral interactions: birth control
impairs zinc and increases copper levels (can lead to dementia)
Drug-mineral interactions: phenytoin, primidone
creates Vitamin B9 (folate) deficiency
Aminosalicyclic acid, slow release K+ iodide, colchicine, ethanol, OC
creates B12 (cobalamin) deficiency
High progestin dose
can cause depression by reducing tryptophan
Orlistat
prevents fat absorption
chloramphenicol, tetracycline
decreases protein
adrenal corticosteroids, ethanol
increases lipids
aspirin, colchicine, glucagon
decreases lipids
antibiotics, fiber, digoxin
decreases appetite
Hypernatremia (elevated Sodium levels)
Causes:
Sx:
Usually due to dehydration; excess diuretics w/ salt intake; N/V with high salt intake
Sx: confusion, neuromuscular excitability, hyperflexia, seizures, cerebrovascular damage with subcortical or subarachnoid hemorrhage
Hyponatremia (decreased sodium levels)
Causes:
Sx:
extrarenal fluid loss; renal fluid loss; diuretics; pancreatitis; rhabdomylosis; opioids, NSAIDS, Addisons disease, hypothyroidism
Sx: lethargy, confusion, altered mental status, stupor, hyperexcitability, hyperreflexia
RED FLAG- refer to ER immediately- saline drip, fluid restriction, removal of diuretics
Hyperkalemia (K+) (for muscle and cell contraction)
Causes:
Sx:
EKG
rhabdomylosis, GI bleed, bleeding ulcers
SX: flaccid paralysis, cardiac tonicity with weakness or paralysis (mostly asymptomatic)
Caution: ACE inhibitors, potassium sparing diuretics, urinary obstruciton, renal failure, heart failure
EKG: short QT wave which will be tall, peaked T wave
Hypokalemia (K+)
Causes:
Sx:
EKG
clay (betonite) ingestion, vomiting, heavy gan cao, chewing tabacco, CUSHINGS,
Sx: muscle weakness, cramping, paralytic ileus, hypoventilation, hypotension, rhabdomylosis
EKG: depression of T wave, elevated U wave
Hypercalcemia (calcium) (note: important for hormone release, blood coagulation, muscle and nerve contraction
Causes:
Sx:
Causes: pagets, osteoporosis, Vit A & D toxicity, Myxedema, Cushings, Addisons
Sx: constipation, polyuria, polydipsia, pancreatitis
Hypocalcemia (calcium)
Causes:
Sx:
Causes: hypoparathyroidism, Vit D xu, renal disease, acute pancreatitis, hypoproteinemia
Sx: carpopedal spasm, parasthesia of lips, fingers and feet, general muscle aching, facial spasms, dry scaly skin, brittle nails
Hyperphosphatemia (phosphorus)
Causes:
Sx:
Causes: hypoparathyroidism; rhabdomylosis
Sx: hypocalcemia, tetany, soft tissue calcemia
Hypophosphatemia (phosphorus)
Causes:
Sx:
Acute alcoholism, undernutrition, hyperparathyroidism, cushings, hypothyroidism, diuretic use, chronic fasting
Sx: anorexia, muscle weakness, osteomalacia, hemolytic anemia
Hypermagnesemia (Magnesium)
Causes:
Sx:
usually uncommon and/or asymptomatic
- respiratory depression, excess antacid use, excess laxative use
Sx: hyporeflexia, hypotension, cardiac arrest
Hypomagnesemia (magnesium)
Causes:
Sx:
alcoholism, steatorrhea, preeclampsia, lactation, thyroid hormone sue, ADH use, polyurea
Sx: anorexia, N/V, lethargy, weakness, personality change, tetany, carpopedal spasm
*caffeine can reduce Mg levels when using in excess
what can cause right upper quadrant pain
cholecystitis and billiary colic; hepatitis, retrocecal appendicitis (rare)
what can cause right lower quadrant pain
appendicitis, cecal diverticulitis, Meckel’s diverticulitis (Crohns)
what can can cause left lower quadrant pain
sigmoid diverticulitis (ulcerative colitis)
What BMI is considered overweight
25-30%
What is a normal pH for saliva and what is it’s function
6.5-7.5 - it moistens and lubricates
what is the pH for bile and what is it’s function
digestion of lipids; 7.5-8.8
A patient comes to you complaining of shoulder issues with limited ROM. They also have extreme thirst, frequent urination, hunger, fatigue, numbness and tingling in the feet and candida. What is your diagnosis?
type 1 diabetes
What is the standard treatment for type 1 diabetes?
What lab tests are done?
Tx: insulin (humalog)
Lab: HbA1C
Patient has dry flushed skin, ketonic breath, nausea and vomiting, cramping, polyuria, blurred vision and foggy head. What is your diagnosis
Type 2 Diabetes
What is the tx for type 2 diabetes?
what is the lab test?
tx: insulin replacement- * Metformin
lab: HbA1C
a patient is sweating, nauseous, warm, has anxiety, palpitations, hunger, and a headache? what is their likely diagnosis?
Hypoglycemia
What is the treatment for hypoglycemia
glucagon
What disease is common in hispanic and african americans and is due to H. Pylori weakening the stomach lining
Peptic Ulcer
NSAIDS and Ethanol can cause pain, nausea, fullness, and bleeding – what disease is this
gastritis
long term asprin use can lead to bleeding ulcers and need to be refered to a physician ASAP- what kind of ulcer is this
Gastric Ulcer
This disorder is caused by H Pylori (mostly) and causes consistent pain which usually awakens a patient at night
Duodenal ulcer
what does melena stand for
black tarry stools due to long term stomach or duodenum bleeding
Amoxil, Cipro, and Levaquin are what kind of common medication?
Antibiotics
what disease is a bacterial diarrhea due to undercooked poultry, milk, eggs or contact with reptiles
Salmonella