Review Flashcards

exam 2

1
Q

Antagonizing leukotriene receptor

A

Asthama

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2
Q

ACE inhibitor can lead to the increase of

A

Bradykinin

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3
Q

Histamine-1

A

lungs; vasodilation, bronchoconstriction

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4
Q

Histamine-2

A

Gastric Acid secretion

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5
Q

Kinins

A

vasodilation, bronchoconstriction, inflammation and pain

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6
Q

Serotonin

A
  • increase sleep nad mood
  • Increase nausea and GI stuff
  • bronchial and smooth muscle constriction
  • Skeletal muscle dilation and flushing
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7
Q

antagonize muscarininc receptors lead to

A

Dry mouth

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8
Q

agonist of muscarininc receptors

A
  • bradychardia
  • bronchoconstriction
  • urinary incotinence
  • sialorrhea
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9
Q
Sympathetic:
Heart Rate
blood vessels
bronchi
pupil
bladder wall
bladder sphincter
A
Heart = Rate increases 
blood = vessels constricts 
bronchi = dilate 
pupil=  dilate
bladder = wall relax
bladder sphincter = constrict
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10
Q
Non-Sympathetic:
Heart Rate
blood vessels
bronchi
pupil
bladder wall
bladder sphincter
A
Heart Rate = decrease
blood vessels =dilate
bronchi = constrict
pupil = constrict
bladder wall =constrict
bladder sphincter = relax
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11
Q

Glaucoma patients Should avoid

A

anti-histamines

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12
Q

epinephrine is used in the lungs to

A

open up the airways

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13
Q

blocking alpha-2 receptor

A

to tx depression

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14
Q

neuronal-plasticity

A

post-synaptic receptors can increase and decrease quantitatively based on the amount of NTT in the cleft

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15
Q

blocking MAO

A

increase NTT in cleft; tx depression

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16
Q

Displace epinephrine with this food type product

A

thymine- like aged cheeses

17
Q

Succinylcholine

A

Depolarizing; only used for intubation… many side effects and thus not used for anything else

18
Q

Non-depolarizing main difference is how

A

they are cleared

19
Q

oral route is preferred in non-depolarizing for a surgical procedure

A

NOOOOOOOOOOOO

does not work.

20
Q

worse side effect in general anesthetics

A

Myocardial depression

21
Q

more potent drugs; _____ MAC

A

lower

22
Q

lower the blood gas partition coefficient the

A

higher the rapid onset of action

23
Q

why is sevoflurane

A

low MAC (more protent) and a relatively low gas partition coefficient (thus rapid onset)

24
Q

local anesthetics work by

A

sodium channel blockade and effect on action potential

25
Q

duration of action will be longer with more

A

protein binding

26
Q

pKa predicts

A

onset of action

27
Q

lipid solubility predicts

A

potency

28
Q

protein binding predicts

A

duration of action

29
Q

local anesthetics block

A

depolarization; slowing the rate of rise