Review Flashcards

exam 2

1
Q

Antagonizing leukotriene receptor

A

Asthama

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2
Q

ACE inhibitor can lead to the increase of

A

Bradykinin

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3
Q

Histamine-1

A

lungs; vasodilation, bronchoconstriction

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4
Q

Histamine-2

A

Gastric Acid secretion

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5
Q

Kinins

A

vasodilation, bronchoconstriction, inflammation and pain

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6
Q

Serotonin

A
  • increase sleep nad mood
  • Increase nausea and GI stuff
  • bronchial and smooth muscle constriction
  • Skeletal muscle dilation and flushing
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7
Q

antagonize muscarininc receptors lead to

A

Dry mouth

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8
Q

agonist of muscarininc receptors

A
  • bradychardia
  • bronchoconstriction
  • urinary incotinence
  • sialorrhea
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9
Q
Sympathetic:
Heart Rate
blood vessels
bronchi
pupil
bladder wall
bladder sphincter
A
Heart = Rate increases 
blood = vessels constricts 
bronchi = dilate 
pupil=  dilate
bladder = wall relax
bladder sphincter = constrict
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10
Q
Non-Sympathetic:
Heart Rate
blood vessels
bronchi
pupil
bladder wall
bladder sphincter
A
Heart Rate = decrease
blood vessels =dilate
bronchi = constrict
pupil = constrict
bladder wall =constrict
bladder sphincter = relax
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11
Q

Glaucoma patients Should avoid

A

anti-histamines

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12
Q

epinephrine is used in the lungs to

A

open up the airways

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13
Q

blocking alpha-2 receptor

A

to tx depression

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14
Q

neuronal-plasticity

A

post-synaptic receptors can increase and decrease quantitatively based on the amount of NTT in the cleft

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15
Q

blocking MAO

A

increase NTT in cleft; tx depression

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16
Q

Displace epinephrine with this food type product

A

thymine- like aged cheeses

17
Q

Succinylcholine

A

Depolarizing; only used for intubation… many side effects and thus not used for anything else

18
Q

Non-depolarizing main difference is how

A

they are cleared

19
Q

oral route is preferred in non-depolarizing for a surgical procedure

A

NOOOOOOOOOOOO

does not work.

20
Q

worse side effect in general anesthetics

A

Myocardial depression

21
Q

more potent drugs; _____ MAC

22
Q

lower the blood gas partition coefficient the

A

higher the rapid onset of action

23
Q

why is sevoflurane

A

low MAC (more protent) and a relatively low gas partition coefficient (thus rapid onset)

24
Q

local anesthetics work by

A

sodium channel blockade and effect on action potential

25
duration of action will be longer with more
protein binding
26
pKa predicts
onset of action
27
lipid solubility predicts
potency
28
protein binding predicts
duration of action
29
local anesthetics block
depolarization; slowing the rate of rise