Review Flashcards
Metabotropic
when glutatate attaches at first nothing happens because mg2+ blocks it
repeated flood of sodium into the cell ejects the magnesium = turns NMDA site into AMPA site
repeated firings of the circuit: then it re-arranges - the more you use it the easier it is
receptor site separate from ion channel (usually)
ionotropic (AMPA)
directly opens a channel that allows sodium to enter the cell
activation of the AMPA sites changes…
…the post-synaptic cell
Dendritization
building new receptor sites
NE
jolt of emotion enables you to remember
absent during REM sleep = maybe why we’re not storing those dreams
Spatial abilities involve
a variety of parts of the brain
hippocampus
Hippocampus and spatial memories
place cells: array of cells, create cognitive map
Retino-hypothalamic path
diaurnal clock - SCN (suprachiasmic nucleus): in the dark you will maintain a rhythm of awake and asleep
- regularity of 24 hours and flexibility to adapt to the seasons
interaction between the hypothalamus (SCN)
from the eye to the SCN to the pineal gland and back
zeitgeber
when full spectrum sunlight enters system it turns on ganglion cells (receptor cells) that follow their own path within the optic nerve to the SCN of the hypothalamus - to inform that nucleus whether it’s day or night
influences exchange of info between pineal gland and SCN
pineal gland
releases melatonin
SCN tells it that it’s day which shuts down production of melatonin
less sun = more melatonin
G-Protein
bonds with second messengers
opens the gate and allows ions to flow into the cell
Metabotropic process
Testes Determining Factor
on Y chromosome
turns on testosterone = directs changes, allows Wolffian system to develop