Reversal Agents Flashcards
1
Q
Warfarin
A
Vitamin K
Phytomenadione
2
Q
Heparin
A
Protamine
3
Q
Dabigatran
A
Ida-ruci-zumab
4
Q
Major Bleeding + Warfarin
A
Stop warfarin
Give intravenous vitamin K 5mg
Prothrombin complex concentrate - if not available then FFP*
5
Q
INR > 8.0
Minor bleeding
On warfarin
A
Stop warfarin
Give intravenous vitamin K 1-3mg
Repeat dose of vitamin K if INR still too high after 24 hours
Restart warfarin when INR < 5.0
6
Q
INR > 8.0
No bleeding
On warfarin
A
Stop warfarin
Give vitamin K 1-5mg by mouth, using the intravenous preparation orally
Repeat dose of vitamin K if INR still too high after 24 hours
Restart when INR < 5.0
7
Q
INR 5.0-8.0
Minor bleeding
On warfarin
A
Stop warfarin
Give intravenous vitamin K 1-3mg
Restart when INR < 5.0
8
Q
Apixaban / Rivoroxaban
A
Andexanet Alfa
