Reumato Flashcards

1
Q

FIBROSIS RETROPERITONEAL LOCALIZADA

A
INFLAMATORIA
AUTOINMUNE
MALIGNIDAD
RDT
QX
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2
Q

FIBROSIS RETROPERITONEAL MULTIFOCAL

A

AUTOINMUNE

NO SE ASOCIA A MALIGNIDAD, NI RDT, NI QX

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3
Q

RAM corticoides

A

Osteoporosis
Glaucoma
Cataratas
HTA
Diabetes
Osteonecrosis
Agitación Psicomotora
Inmunosupresion
Aumento de peso
Fragilidad cutánea

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4
Q

Uso corticoides y riesgo fractura ósea

A

Bifosfonatos

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5
Q

Cómo viajan los corticoides en el plasma

A

Unidos a:
Corticoid binding protein
Albumina

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6
Q

Methotrexate

A

Antimetabolito del folato
Inhibe síntesis de dna

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7
Q

Leflunomida

A

Inhibe síntesis de pirimidina: anti proliferativo y anti inflamatorio

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8
Q

Azatioprina

A

6 mercqptopurina, inhibe síntesis de dna

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9
Q

Ciclofosfamida

A

Agente alkilizante, inhibe el ciclo celular al bloquear la división celular

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10
Q

Micofenolato

A

Inhibe la síntesis de purina: células b y T

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11
Q

Hidroxicloroquina

A

Inmunomodulador
Inhibe las vacuolas lisosomales

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12
Q

Alopurinol, mecanismo de accion

A

Bloquea la enxima xantina oxidasa, por lo que bloquea la conversión de hipoxantina a ácido úrico

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13
Q

Hidroxicloroquina y embarazo

A

Relativamente segura

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14
Q

Screening pre inmunosupresiópn

A

IGRA
VHB VHC
VIH

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15
Q

Factor riesgo para AR

A

Tabaquismo

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16
Q

Compromiso articular en AR

A

MCF
MTF
IFP
Grandes articulaciones
Simétricas
De distal a proximal