Retinal Vascular Disease Flashcards

0
Q

What’s malignant hypertension

A

High BP

Arteriolar fibrinoid necrosis

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1
Q

What’s hypertensive retinopathy

A

Due to damage by raised BP- Damage to blood vessels
Focal arteriolar narrowing, Arteriosclerotic changes and nerve fibre heammohrage

For accelerated hypertension u see macular star, cotton wool spots and disc odeama

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2
Q

Central retinal vein occlusion- could be due to 1.mechanical constriction at lamina cibrosa or due to 2.Hemodynamic factors which obstruct blood flow

A
  • Retinal veins are dilated
  • va worse than 6/36
  • visual loss may occur when asleep
  • haemorrhages- superficial and deep which could lead to ischeamia
  • afferent pupillary defect
  • lots of cotton wool spots
  • odeama
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3
Q

How would u manage CRVO

A
Investigate RF
Maximise recovery and va
Prevent re occlusion
Treat any underlying cause
Is it Ischeamic or not 
Laser pan retinal photo coagulation for any neovas
Prevent glaucoma 
Protect other eye
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4
Q

What are the risk factors for CRVO

A
Hypertension 
Diabetes mellitus
Smoking
POA glaucoma 
Hyperviscosity
Hyperlipdeamia
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5
Q

Investigation for CRVO

A

Blood test and sugar levels checked
Urine analysis
Under age of 50- look for clotting abnormalities- likely to get thrombis.

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6
Q

central retinal vein occlusion clinical features

A
ISCHEAMIC- 
Sudden loss of vision
Less than 6/36
Multiple dark heammohrages
Lots o cotton wool spots 
Likely to develop rubeosis irisdis 

NON ISCHEAMIC-
Younger age
Vision between 6/36-6/60
Less dark heammohrages and cotton wool spots
Less likely rubeosis iridis
About a third of these cases turn schematic. Dud dud dud

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7
Q

What complications arrise with CRVO. Look at this fancy question

A

You can get rubeosis iridis-ISCHEAMIC damage that stimulates vegFs to grow iris to anterior chamber
Central macular odema- unresponsive to laser so need intraretinal injections
Neovascular glaucoma- high IOP
Neovascularisation

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8
Q

BRVO

A

Appearance depends On which vessel-specific quad or Ono macular
Haemmorages cotton wool spots and exudates
Occlusion occurs at arterior vein crossing
Visual prognosis depends if macular involved

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9
Q

How would u manage BRVO

A

Investigate the systemic cause
Some may get better spontaneously
Laser photo coagulation for new vessels
And focal laser for macular odeama

Tell them to avoid oral contraceptives
Take aspirin
Treat hypertension
Lower IOP 
Anticoagulant?
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10
Q

How would u manage cmo

A

Intra vitreal injection
Reduces it
For a couple of months

Side effects being cataract and raised IOP

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11
Q

What are the risk factors for BRVO

A

Hypertension
Cardio vascular disease
Lipid abnormality

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12
Q

Artery occlusion types and risk factors

A

Central retinal artery occlusion
Branch retinal artery occlusion
Cilo retinal arteries

Rf hypertension 
Smoking 
Diabetes
Hyperlipideama
Carotid bruits
Emboli 
Vascular disease
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13
Q

How would u manage retinal artery occlusion

A

Rebreath co2 from bag
Lower the IOP
Digital massage of globe

In hosp u do anterior chamber paracentesis

Look for underlying cause. Check heart and carotid arteries. Treat these causes

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14
Q

Giant cell arteritis. Aka temporal arteritis

A

ISCHEAMIC ON
Both optic disc swollen and pale as occlusion of posterior ciliary artery
Elderly Px
Occlusion of arteries in head and neck

Sx- weight loss, stiffness in neck, tenderness of scalp. Doctor needs to see. Confirmed by esr blood test. May need biopsy to test. Need STEROIDS as both eyes can be involved v quickly

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15
Q

Macro aneurysms

A

Little aneurysms
Out pouching of vessels
Surrounding u can get exudates or vitreous haemmohrage

Associated with hypertension or carotid artery disease

Laser??

16
Q

Vascular tunours

A
RARE
Choroidal angioma
Retinal angioma
Cerebullar tumours
Coats disease
17
Q

Radiation retinopathy

A

Due to radiation
Those people who have radiation for neck and throat tumour
U see haemmohrage and exudates

18
Q

Retinopathy prematurity

A

Less than 30weeks less than 1300g
Proliferative retinopathy
High levels of O2

Classification
Stage 1- demarcation line
Stage 2- ridge
Stage 3- fibrovascular proliferation and scar tissue 
Stage 4- RD
Stage 5- total tractional RD

Treat with laser
1/3 go away themselves

19
Q

Connective tissue disorders

A
Sheathing of vessel wall
Cotton wool spots
New vessels 
Vitreous heammohrages 
Vitreous cells
20
Q

Collagen disorders

A

Systemic lupus iridothosis
Polyarteritis nodosa

Inflammatory disorders affecting retinal blood vessels

21
Q

What are the blood disorders

A

Anaemia
Lukeamia
Heamoglobinopathies
Hyper viscosity syndrome

22
Q

features of sickle cell

A
Painful joints
Bone marrow infarcts 
Abdominal pain 
Necrosis head of femur 
Pulmonary infarcts 
CNs infarcts
RE dysfunction
Salmonella infection 
Retinopathy - affect peripheral retina- can cause sea fans which can burst and cause a heommohrage
Can get iris atrophy or synechie 
Flare and cells in anterior chamber
Retinopathy in post segment
23
Q

How would u treat sickle cell

A

Observe
Laser scatter photo coagulation
Vitrectomy if bleed
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