RETINA - RETINAL TUMORS Flashcards

1
Q

what are 3 retinal tumors?

A
  1. retinoblastoma
  2. primary introcular lymphoma
  3. CHRPE
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2
Q

what is the most common primary intraocular malignancy (tumor) in children?

A

retinoblastoma

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3
Q

what is retinoblastoma?

A

Malignant transformation of primitive retinal cells occurs before they undergo final differentiation

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4
Q

what age does retinoblastoma occur?

A

<5 y/o

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5
Q

symptoms of retinoblastoma?

A
  • unilateral leukocoria
  • possible strabismus
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6
Q

signs of retinoblastoma?

A
  • unilateral leukocoria
  • dome shaped yellow-white globular mass
  • uveitis
  • pseudohypopyon
  • secondary glaucoma
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7
Q

w/u for retinblastoma?

A
  • DFE
  • B-scan
  • CT scan
  • MRI
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8
Q

tx/managment for retnoblastoma?

A
  • refer to ophthamologist
  • enucleation (removal of eye but leaves EOMS & other orbital content intact).
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9
Q

prognosis for retinoblastoma?

A

good - survial rate is 85-90%

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10
Q

what is a CHRPE?

A

benign congenital hypertrophy

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11
Q

how to distinguish between choroidal nevi & CHRPE

A
  • use red-free filter –> CHRPE will remain while nevus will dissapear with red-free filter.
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12
Q

symptoms of CHRPE?

A

asymptomatic

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13
Q

signs of CHRPE?

A
  • singular flat brown (hyperpigmentation) freckle which will not dissapear w/ red-free filter.
  • CHRPE may have central hypopigmentation called lacunae.
  • multiple CHRPE is known as bear tracks.
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14
Q

Muliple CHRPE’s (>40) & bilateral can be associated with what systemic condition?

A

Gardner’s syndrome (colon cancer)

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15
Q

tx for CHRPE?

A
  • single CHRPE - no tx, monitor & photographed
  • Multiple, bilateral CHRPE’s - refer for colonoscopy (possible gardner syndrome or FAP).
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16
Q

what is primary intraocular lymphoma (primary CNS lymphoma)?

A

tumor that begins in the brain but can manifest in the eye.

17
Q

what is the prognosis for primary intraocular lymphoma (primary CNS lymphoma)?

A

poor - death w/in 2 yrs of dx.

18
Q

symptoms for primary intraocular lymphoma

A

blurry vision
floaters

19
Q

signs for primary intraocular lymphoma

A
  • panuveitis
  • yellow-white PED
  • serous retinal detachments
  • nerve edema
20
Q

tx for primary intraocular lymphoma

A
  • refer to oncologist - chemotherapy the lymphoma
  • dx can be confirmed with LP & brain MRI