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Retina / Uveitis > Retina > Flashcards

Retina Flashcards

1
Q

What is the most common cause of CWS?

A

DR

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2
Q

What systemic dz was found not to contribute to BRVO in the BVOS?

A

Diabetes

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3
Q

What is the most frequent cause of endogenous endophthalmitis after LIVER transplants?

A

Aspergillus (mold)

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4
Q

Congenital color vision defect has what inheritance pattern and who is affected more?

A

XLinked recessive; males 5-8%; 0.5% females

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5
Q

Which makes up the largest group of color-deficient persons?

A

Anomalous trichromats - “color weak”

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6
Q

The cone-rod homeobox-containing gene (AD) causes what 2 dz?

A
  1. Leber congenital amaurosis

2. Cone-Rod dystrophy

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7
Q

Rhodopsin (AD) gene defect causes what 2 dz?

A
  1. CSNB

2. RP

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8
Q

RDS-Peripherin gene (AD) casues what 3 dz?

A
  1. Cone-Rod dystrophy
  2. RP
  3. Pattern dystrophy
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9
Q

What are redudant fold of peripheral retina that project into the vitreous and are located in the superonasal quadrant?

A

Meriodial folds - risk for retinal tear

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10
Q

Muller cell nuclei are located in what layer?

A

Inner nuclear layer

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11
Q

What is psoralen?

A

Drug that treats extensive vitaligo and other skin d/o. It photosensitizes the eye.

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12
Q

MAR has antibodies to what cells?

A

Retinal bipolar cells in the Inner nuclear layer; MAR predominantly affects RODS

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13
Q

What are risk factors for developing AMD?

A
  1. HYPEROPIA
  2. HYN
  3. Hypercholesterolemia
  4. FEMALE
  5. Fhx
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14
Q

Methionine restriction, high cystine, and Vitamin B6 supplementation is recommended for what dz?

A

Homocystinuria

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15
Q

Phytanic acid restriction is recommended in what dz?

A

Refsum dz

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16
Q

Vitamin A and E supplementation is recommended in what dz?

A

Abetalipoprotenemia

17
Q

What are 2 protective factors?

A
  1. darker fundus pigmentation

2. high refractive errors

18
Q

Nitrofuritonin causes what type of retinopathy?

A

Crystaline retinopathy

19
Q

Most hereditary color defects are what inheritance?

A

XL recessive

20
Q

Rod monochormatism is what inheritance?

A

AR

21
Q

tritanopia/anomolous is what inheritance?

A

AD

22
Q

What are 5 lesions that predispose to RD?

A
  1. LD
  2. VR tuft (noncystic, cystic, zonular traction retinal tufts)
  3. Meridional folds
  4. Enclosed ora bays
  5. Peripheral retinal excavations - atypical LD
23
Q

In MAR antibodies are directed against what cells?

A

Bipolar cells

24
Q

How do you differentiate gyrate atrophy from choroideremia?

A 
Gyrate atrophy (AR) has generalized hyperpigmentation of the remaining RPE
Choroideremia - X linked recessive rod-cone dystrophy
25
Q

Retinal astrocytic hamartoma?

A

Tuberous sclerosis

26
Q

Gyrate atrophy lacking what and treat how?

A

Ornathine uridyl transferase
And
Arginine restricted diet + vit B6 (pyridoxine)

27
Q

List 3 things that cause retinal wipeout.

A
  1. Bechets
  2. ARN
  3. DUSN
28
Q

How do you treat Bartonella hensale?

A

Cipro 500 bid

29
Q

Which retinal necrosis retinitis responds well to IV acyclovir and which one responds poorly?

A

Well - ARN

Poor - PORN

30
Q

List 2 RP like diseases that can be treated.

A
  1. Bassen-kornzweig (abetalipoproteinemia + acantholysis) - supplement vitamin A,D,E,K)
  2. Refsums dz - (cerebellar ataxia with ichthyosis) elevated phtyanic acid; restrict it in the diet
31
Q

What has medium to low internal reflectivity?

What has high internal reflectivity?

What has medium to high internal reflectivity?

A
  1. Chorodial melanoma
  2. Chorodial hemangioma
  3. Metastatic choroidal tumors
32
Q

What % of RB is sporadic?

Germinal mutation?

A

60% - sporadic
40% - heritable

Sporadic - 94% of unilateral dz

Germinal (heritable) - 20-30% cases (80% - bilateral)

Somatic (non-heritable)

33
Q

Match the retinal vasculitis with dz and vessel size:

  1. GCA
  2. Wegeners
  3. Polyartritis nodosa
A
  1. Large vessel
  2. Small and medium vessels
  3. Medium vessels
34
Q

White string of pearls in the vitreous is what?

A

Amylodisis

35
Q

Ddx of crystalline retinopathy?

Genetic vs toxic vs vascular vs metabolic

A

Genetic - bietti’s (rpe changes and nyclopia); gyrate; cystinosis

Toxic - tamoxifen, nitrofuitonin, canthaxanthine, methoxyflurane

Vascular - jxt

Metabolic - sarcoid; liver cirrhosis; renal failure

Retina / Uveitis (2 decks)

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