reticular formation Flashcards
raphe nuclei
immediately adjacent to sagittal plane on each side
what are the three longitudinal zones
raphe nuclei
medial zone
lateral zone
medial zone
alongside raphe, mixture of large and small neurons, source of most ascending and descending projections
lateral zone
prominent in rostral medulla and caudal pons, primarily involved in cranial nerve reflexes and visceral functions
reticular formation neurons…
have extensive, complex connections; may innervate multiple levels of spinal cord, brainstem and thalamus
the reticular formation is phylogenetically ____ and the central core of the ________
old, brainstem
rf extends in the cerebrum as the
hypothalamus
rf is important in the regulation of
posture stereotypic motor behaviors pain regulation sleep and wakefulness emotional tone
two reticulospinal tracts
medial and lateral
medial reticulospinal tract
pons; ipsilateral, descends near MLF and in anterior funiculus
lateral reticulospinal tract
medulla; descends bilaterally in lateral funiculus
reticular formation and movement
major alternative to corticospinal tract in regulating spinal motor neurons
influences spinal motor neurons _______
directly
regulates spinal reflexes
so that only noxious stimuli evoke a reflex
reticulospinal tract neurons receive input from many areas including
cerebral cortex, basal ganglia, substantia nigra, etc
rf contains basic neural machinery for
some complex patterned movements
rhythmic motor patterns
gaze centers, mastication (pons), locomotion (pons),
heart rate, respiration, swallowing, vomiting (medulla “vital center”)
2 theories of what causes bruxism
peripheral causes theory and central causes theory
central causes theory
sleep-related dysfunctions cause bruxism
input to supratrigeminal nucleus may be from basal ganglia, lateral hypothalamus, and central nucleus of the amygdala
rf modulates transmission in
pain pathways
nervous system can ______ or __________ pain, depending on curcumstances
suppress, facilitate
wounded soldiers on the battlefield who continue to function
*rf is key to these functions
_________ ________ is central to one well described pain suppress system
periaqueductal gray
_____ receives pain info spinomesencephalic fibers
PAG
PAG also gets input from
hypothalamus, cortex, ect; may contain behavioral state info
—should pain suppression be activated
PAG to ______ then to _________
raphe, posterior horn of spinal cord/spinal V nucleus
One way opiates work to control pain is to
activate PAG-raphe at multiple levels
Opiate receptors are abundant in
PAG, raphe, posterior horn of cord
raphe can inhibit STT directly or indirectly by activating ________ that inhibit STT
interneurons
can also directly inhibit pain afferents