Resuscitation in special circumstances Flashcards
How does acidosis affect serum potassium levels?
acidaemia causes an increase in serum potassium
List causes of Hyperkalaemia
- Renal failure
- Drugs (ACEI, ARB, Spiro, NSAID, BB, trimethoprim)
- tissue breakdown (rhabdo, tumour lysis, haemolysis, burns)
- Metabolic acidosis (DKA, renal failure)
- endocrine (addisons)
- spurious (clotted)
What ECG changes are seen with hyperkalaemia?
- Tall tented T waves (taller than R wave in more than one lead)
- short QT interval
- 1st degree AV block
- bradycardia
- ST depression
- flat or absent P waves
- Wide QRS
- Merging of S and T wave (sine wave pattern)
- VT
define mild hyperkalaemia. Treatment?
K5.5-5.9
address cause to correct (drugs/diet etc)
resonium
consider IV fluids
define moderate hyperkalaemia. Treatment?
K6-6.4, NO ECG changes
Shift K intracellularly - insulin 10U and 25g of glucose. monitor BSL. (onset 15-30min, max effect 30-60min, duration of action 4-6hr
remove K from the body - resonium
define severe hyperkalaemia. Treatment?
K>6.5
Seek help
ECG, if changes: 5-10mL 10% calcium chloride IV over 2-5min
shift K intracellularly - 10U insulin, 25g glucose. Salbutamol Nebs
Remove K from body - Resonium/Dialysis
consider IV fluids
Consider sodium bicarb 50mmol IV if severe acidosis or renal failure
Considerations for ALS during haemodialysis
ALS as normal
stop ultrafiltration (fluid removal)
fluid bolus
return patients blood volume and disconnect from the machine (some dialysis machines are defibrillator-proof tho)
leave dialysis access for drug admin
All Hs and Ts apply, but hyperK and APO are most common
What are the causes for hypokalaemia?
- GI losses (diarrhoea)
- Drugs (diuretics, laxatives, steroids)
- Renal (Renal tubular disorders, DI, dialysis)
- Endo (Cushings, hyperaldosteronism)
- Metabolic alkalosis
- magnesium depletion
- poor intake
Symptoms of hypokalaemia
- nerves and muscles mostly affected
- fatigue, weakness, cramps
- constipation
- in severe cases: rhabdo, ascending paralysis, resp muscle weakness
What are the ECG changes in hypokalaemia?
- U waves
- Flat T waves
- ST segment changes
- arrhythmias including AF, esp if on digoxin
Treatment of hypokalaemia periarrest and arrest?
Periarrest: 20mmol/hour or can go 2mmol/min for 10 min followed by 10mmol overe 5-10min
Arrest: 5mmol bolus followed by Mag 2g
giving Mg after K helps K uptake and maintenance of intracellular K particularly in the myocardium
Normal total calcium and ionized calcium levels? What is corrected Ca correcting for?
Total Ca: 2.2-2.6 mmol/L
Ionized Ca: 1.1-1.3mmol/L
corrected corrects for serum albumin
Causes of hypercalcaemia
- Primary or tertiary hyperparathyroidism
- Malignancy
- sarcoidosis
- drugs
Causes of hypocalcaemia
- chronic renal failure
- pancreatitis
- calcium channel blocker OD
- toxic shock syndrome
- Rhabdomyolysis
- tumour lysis syndrome
Causes of hypermagnesaemia
- renal failure
- iatrogenic
Causes of hypomagnesaemia
- GI loss
- polyuria
- starvation
- alcoholism
- malabsorption
Symptoms of hypercalcaemia
- Painful bones
- stones (renal and chole)
- abdominal pain (N/V/D)
- pysch tones
- cardiac - hypotension, arrhythmia, arrest
Symptoms of hypocalcaemia
- paraesthesia
- tetany
- seizures
- AV block
- arrest
Symptoms of hypermagnesaemia
- confusion
- weakness
- resp depression
- AV block
- arrest
Symptoms of hypomagnesaemia
- tremor
- ataxia
- nystagmus
- seizures
- TdP
- arrest
Treatment of hypercalcaemia
- IVT
- Frusemide
- hydrocortisone
- pamidronate
- treat cause