Restrictive Lung Dysfunction Flashcards
T/F: RLD is a disease.
FALSE, just dysfunction
RLD is an abnormal reduction in __ __, or to simply put it a ventilatory pump dysfunction.
Pulmonary ventilation
The pathogenesis of RLD includes an increased resistance to lung expansion, decreasing lung and/or chest wall __. In addition, all lung volumes and capacities are (incr./decr.) and work of breathing is increase due to need for greater ___ pressure.
1) compliance
2) decreased
3) transpulmonary
PFT values in RLD:
FVC = __ %
FEV1 = low, but compared to FVC is __
FEV1/FVC = __ %
FVC = ≤ 80%
FEV1 = low, but FVC decline is GREATER than FEV1
FEV1/FVC = ≥ 80%
Signs of RLD include __pnea, __exmia, decreased breath __, decr. vol/capacities, decr. diffusing capacity, __ __ (think R-sided HF), reticulonodular pattern on imaging, & pulmonary __tension.
1) TACHYpnea
2) HYPOxemia
3) sounds
4) cor pulmonale
5) HYPERtension
4 symptoms of RLD are…
Dyspnea
Cough
Wt loss
Muscle Wasting
One maturational cause of RLD is __ or hyaline membrane disease. This is a disorder of prematurity with a lack of complete lung maturation. Its linked to gestational age and caused by surfactant abnormalities and reduced production.
Infant respiratory distress syndrome
Another maturational cause of RLD normal aging, which is complicated by ___ factors like pollution, gases, job exposures, drugs, & smoking. Lung changes with normal aging include decreased __ at 20 y/o, max voluntary __ & __ __ decreased, less sensitive chemoreceptors, decalcification/arthritic changes in the __, enlargement of air spaces, and decreased ___ __ (think elasticity).
1) environmental
2) compliance
3&4) ventilation & Vital Capacity (VC)
4) ribs
5) elastic recoil
Pulmonary causes include fibrosis, asbestosis, pneumonia, atelectasis, PE, pulmonary edema, bronchogenic carcinoma, etc. Pretty much any the makes __ more difficult.
inspiration/inhalation
3 types of bronchogenic carcinoma are what?
Which one is the most common?
Which one is the rarest type?
1) SCLC (small cell), NSCLC (non-small cell), & carcinoid tumors
2) NSCLC
3) carcinoid tumors
NM causes include amyotrophic lateral sclerosis, poliomyelitis, tetanus, and myastenia gravis. Name 3 more NM causes.
1) SCI C3-C5 keep the body alive
2) GBS
3) Duchenne Muscular Dystrophy and other muscular dystrophies
What N innervates the diaphragm?
Phrenic N
Some MSK causes include kyphoscoliosis, pectus excavatum/carinatum, SC fx, lung contusion, burns, surgery, & penetrating wound. What are 2 more MSK causes of RLD?
Hint: 1 deals with a fx. We’ve talking about both conditions in MSK 3
1) rib fx
2) ankylosing spondylitis
Name 3 connective tissue causes of RLD besides polymyositis and dermatomyositis.
Hint: one has a unique S&S involving the skin
1) RA
2) Regular or drug induced SLE (lupus)
3) scleroderma
T/F: Pregnancy can also be a cause of RLD. A contributing factor is a decrease in chest wall compliance d/t decr. downward excursion of the diaphragm. In the 1st trimester ventilation to dependent regions of lungs is impaired d/t fetus.
FALSE; everything is true EXCEPT ventilation to dependent region is impaired in the THIRD trimester.