Restless Leg Syndrome

Question 1

Which lab value should be checked when a patient presents with RLS?

Answer 1

iron. Assess ferritin, iron stores

Question 2

What is the order of therapy for RLS?

Answer 2

Iron
Gabapentin/pregabalin (Contraindicated if patient has history of substance abuse)
Dopamine agonists: pramiprexole, ropinorole
*often dosed at night
*sedation orthostasis, psych related concerns (schizo, which is characterized by too much dopa), edema, rare reports of obsessive behavior
Sinemet
*dosed once daily typically at night = for RLS, can also be used PRN