Resting and Action Potential Flashcards
Resting Potential
Membrane voltage of a resting cell, negative charge
Levels of K+ and Na+Cl- at Resting Potential
Hi K+ on the inside and hi Na+Cl- on the outside
Why does K+ move to the inside
Because of its hi-concentration and hi permeability, it moves in to balance the negative charge of the large proteins that can’t leave the cell
Na+
Not very permeable and has to be pumped out
Voltage gated Na+ Channel
an innovation that excitable cells have, has the activation gate and the inactivation gate
Activation Gate
Closed at RP
Inactivation Gate
Open at RP when the surrounding membrane depolarizes , allowing Na+ to rush in and create an AP
Depolarizes
becomes less negative on the inside
Axon Hillock
Action potentials normally start here
Threshold
If depolarization reaches this, an AP is irreversibly fired
Schwann Cells
Myelinated axons outside brain and spinal cord
Oligodendrocytes
Myelinate in CNS
What happens at threshold
Activation gate of V-gated Na+ channel opens and lets Na+ rush in and discharge membrane voltage
Nodes of Ranvier
Space between myelin, bare membrane, where AP occurs
Unmyelinated axons
APs flow smoothly towards synapse