Rest Of Chapters Flashcards
Management for K+ of 7.2 mmol/L ?
IV 10ml 10% calcium gluconate
10 units rapid acting insulin given in 100mls 20% dextrose over 30 mins
Consider salbutamol 10-20mg NEB
Whats the risk of metformin in AKI?
Risk of lactic acidosis due to renal excretion mechanism
What diabetic drug to give if not overweight?
Sulphonylurea - glipizide
Classic side effects of vancomycin?
Nephrotoxocity and ototoxicity
Check required before vancomycin use?
Kidney function/creatinine
What drug to give concurrent if prescribing methotrexate ?
Folic acid
What to check before starting methotrexate?
FBC, LFT, kidney fx
What kind of toxicities can methotrexate cause
FBC, LFTs, lung, GI
What to check before starting statin
LFT
What to check before starting amiodarone
TFT, LFT, K+, U&Es
What kind of toxicities can occur from amiodarone
Eyes, lft, lung, tft
What to check before starting gentamicin
Kidney
What to check before starting olanzipine
Fasting blood glucose
Drugs to avoid in pregnancy
Antibiotics tetracyclines aminoglycosides sulphonamides and trimethoprim quinolones
Other drugs ACE inhibitors, angiotensin II receptor antagonists statins warfarin sulfonylureas retinoids (including topical) cytotoxic agents
Whats the increment or decrement amounts for levothyroxine?
25-50micrograms
What antiepileptic drug might cause a low sodium?
Carbamazepine - SIADH
What paradoxical thing might happen when aggressively loading someone with IV fluids?
Might get increase urine output - must match urine output/hour with fluid input/hour
What to do when on broad spectrum antibiotics and ppi?
Stop ppi
What GI symptoms can a PPI like lansoprazole cause?
Diarrhea or constipation, abdominal pain
In t1dm and DKA, how should insulin requirement be managed?
Stopped quick acting insulin, continue long acting insulin, start fixed rate IV insulin infusion
What opiate is suitable for use in AKI or renal impairment?
Oxycodone
What to do with amiodarone if in thyrotoxicosis?
Stop amiodarone
prednisolone does what to WCC?
slightly raise
side effects of steroids
DEMONIC SHIRT
Diabetes Edema Mood swings/depression/delirium Osteoporosis Necrosis of fem head Infection Cushings/cataracts
Skin thinning/striae Hirsutism/hypertension Impaired wound healing R/L heart failure Tummy ulcers
treating congestive heart failure
UNLOAD FAST
Upright Nitrates Loop diuretic (furusemide) Oxygen ACEi Digoxin
Fluids (decrease)
Afteroid (decrease
Sodium restriction
Test (digoxin level, ABGs, potassium)
what time to take sulphonylureas?
morning - avoid overnight hypos
definition of flare of ulcerative colitis?
more than 6 bowel movements and unwell
what to do in severe flare of ulcerative colitis?
IV hydrocortisone and IV fluids
what to do in mild flare of ulcerative colitis?
oral prednisolone 30mg over 24 hours
In UTI if eGFR is 39, which antibiotic is preferred?
Trimethoprim
What kind drugs interact with hormonal contraceptive pills?
Anti-epileptics e.g topiramate, thalidomide
What is the more common side effect of beta blocker other than bradycardia
Erectile dysfunction
What electrolyte imbalance can dalteparin cause?
Hyperkalaemia
What should be done with allopurinol in AKI?
Withhold due to renal accumulation
What can co-amoxiclav do to skin color
Jaundice - hepatotoxic
What patient parameter should be used to monitor response to furosemide in fluid overload?
Weight
What patient parameter should be used to monitor response to ACEI in heart failure?
Exercise tolerance
By how many % is safe to increase insulin dose?
10%
Risk of too much low molecular weight heparin ?
Heparin induced thrombocytopenia
