Rest Of Chapters Flashcards

1
Q

Management for K+ of 7.2 mmol/L ?

A

IV 10ml 10% calcium gluconate
10 units rapid acting insulin given in 100mls 20% dextrose over 30 mins

Consider salbutamol 10-20mg NEB

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2
Q

Whats the risk of metformin in AKI?

A

Risk of lactic acidosis due to renal excretion mechanism

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3
Q

What diabetic drug to give if not overweight?

A

Sulphonylurea - glipizide

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4
Q

Classic side effects of vancomycin?

A

Nephrotoxocity and ototoxicity

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5
Q

Check required before vancomycin use?

A

Kidney function/creatinine

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6
Q

What drug to give concurrent if prescribing methotrexate ?

A

Folic acid

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7
Q

What to check before starting methotrexate?

A

FBC, LFT, kidney fx

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8
Q

What kind of toxicities can methotrexate cause

A

FBC, LFTs, lung, GI

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9
Q

What to check before starting statin

A

LFT

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10
Q

What to check before starting amiodarone

A

TFT, LFT, K+, U&Es

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11
Q

What kind of toxicities can occur from amiodarone

A

Eyes, lft, lung, tft

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12
Q

What to check before starting gentamicin

A

Kidney

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13
Q

What to check before starting olanzipine

A

Fasting blood glucose

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14
Q

Drugs to avoid in pregnancy

A
Antibiotics
tetracyclines
aminoglycosides
sulphonamides and trimethoprim
quinolones
Other drugs
ACE inhibitors, angiotensin II receptor antagonists
statins
warfarin
sulfonylureas
retinoids (including topical)
cytotoxic agents
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15
Q

Whats the increment or decrement amounts for levothyroxine?

A

25-50micrograms

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16
Q

What antiepileptic drug might cause a low sodium?

A

Carbamazepine - SIADH

17
Q

What paradoxical thing might happen when aggressively loading someone with IV fluids?

A

Might get increase urine output - must match urine output/hour with fluid input/hour

18
Q

What to do when on broad spectrum antibiotics and ppi?

A

Stop ppi

19
Q

What GI symptoms can a PPI like lansoprazole cause?

A

Diarrhea or constipation, abdominal pain

20
Q

In t1dm and DKA, how should insulin requirement be managed?

A

Stopped quick acting insulin, continue long acting insulin, start fixed rate IV insulin infusion

21
Q

What opiate is suitable for use in AKI or renal impairment?

A

Oxycodone

22
Q

What to do with amiodarone if in thyrotoxicosis?

A

Stop amiodarone

23
Q

prednisolone does what to WCC?

A

slightly raise

24
Q

side effects of steroids

DEMONIC SHIRT

A
Diabetes
Edema
Mood swings/depression/delirium
Osteoporosis
Necrosis of fem head
Infection
Cushings/cataracts
Skin thinning/striae
Hirsutism/hypertension
Impaired wound healing
R/L heart failure
Tummy ulcers
25
Q

treating congestive heart failure

UNLOAD FAST

A
Upright
Nitrates
Loop diuretic (furusemide)
Oxygen
ACEi
Digoxin

Fluids (decrease)
Afteroid (decrease
Sodium restriction
Test (digoxin level, ABGs, potassium)

26
Q

what time to take sulphonylureas?

A

morning - avoid overnight hypos

27
Q

definition of flare of ulcerative colitis?

A

more than 6 bowel movements and unwell

28
Q

what to do in severe flare of ulcerative colitis?

A

IV hydrocortisone and IV fluids

29
Q

what to do in mild flare of ulcerative colitis?

A

oral prednisolone 30mg over 24 hours

30
Q

In UTI if eGFR is 39, which antibiotic is preferred?

A

Trimethoprim

31
Q

What kind drugs interact with hormonal contraceptive pills?

A

Anti-epileptics e.g topiramate, thalidomide

32
Q

What is the more common side effect of beta blocker other than bradycardia

A

Erectile dysfunction

33
Q

What electrolyte imbalance can dalteparin cause?

A

Hyperkalaemia

34
Q

What should be done with allopurinol in AKI?

A

Withhold due to renal accumulation

35
Q

What can co-amoxiclav do to skin color

A

Jaundice - hepatotoxic

36
Q

What patient parameter should be used to monitor response to furosemide in fluid overload?

A

Weight

37
Q

What patient parameter should be used to monitor response to ACEI in heart failure?

A

Exercise tolerance

38
Q

By how many % is safe to increase insulin dose?

A

10%

39
Q

Risk of too much low molecular weight heparin ?

A

Heparin induced thrombocytopenia