Rest of Cell Metabolism 2 Flashcards
1
Q
5 main classes of lipids?
A
- Free fatty acids
- Triacyglycerols
- Phospholipids
- Gycolipids
- Steroids
2
Q
How does triaglycerol keep the pH in a normal range?
A
Ester linkages neutralise carboxylic acids
3
Q
Which two enzymes does lipogenesis involve?
A
Acetyl CoA Carboxylase and Fatty acid synthase
4
Q
Sequential reactions in lipogenesis?
A
Sequential decarboxylative condensation reactions
5
Q
3 differences between Beta oxidation and fatty acid synthesis?
A
- CoA vs ACP carrier
- NADPH vs FAD/NAD+ (where reducing power is coming from)
- Mitochondrial Matrix vs cytoplasm
6
Q
Where is FA synthesis normally restricted to?
A
Liver, adipose tissue and lactating breast
7
Q
Medium chain acyl-coenzyme A dehydrogenase deficiency (MCADD)?
A
Autosomal recessive. Can be fatal, patients need a high carb diet
