Respiratory Ventilation Flashcards
what are the two types of respiration taking place within the body?
external respiration: which takes the gases (fresh air) from the environment and brings them into the lung
internal respiration: taking the gases from the blood and using it in the cells during cellular respiration
what is external respiration?
(another name) & what does the process include
also called ventilation
- takes environmental air into the lungs via inspiration
- removes waste product of CO2 from alveoli back to the environment via expiration
structures within the conduit (conduction portion of the airway)
& their function
structures
- nose
- pharynx
- trachea
- bronchi
- terminal bronchioles
function
- low resistance pathway allows for easy flow to lungs
- moistens the air
-nose filters
- protects against and removes FB, particles, etc.
How is the tracho-bronchial tree set up? which zones are conducting? which zones are respiratory?
tracho-bronchial tree is a dichotomous tree – each branch becomes 2
conducting zone: zones 0-16 where gas is just passing though (no gas exchange)
respiratory zone: 17-23 where gas exchange occurs –> the respiratory bronchioles, alveolar ducts and alveolar sacs
** sacs = majority of gas exchange**
what is the respiratory portion of the airway?
& whats its function
structures
- respiratory bronchioles
- alveolar ducts
- alveolar sacs
- alveoli
function
- gas exchange
cell types within the alveoli
how do they interact with the capillary at the pulmonary interface?
- type 1 pneumocyte: responsible for the exchange of gas via diffusion
- type 2 pneumocyte: responsible for creating surfactant
Pulmonary interface –> connection between the basement membrane of the T1P and the capillary
- the basement membrane fuses with the capillary (THIN) to create this surface
** as large as a tennis court**
What forces are involved in ventilation?
ventilation: the force of moving air in and out of the lungs to effective reach the pulmonary interface
- muscles of respiration
- respiratory pressure
- surfactant
explain the muscles of respiration and how they work
- diaphragm
- pulls DOWN on inhalation - external intercostal muscles
- pull OUT on inhalation
Result: collectively allows lungs to inflate as chest expands
- diaphragm
- relaxes back up - internal intercostal muscles contract
- pulls in
- lungs recoil – where they want to be
Result: chest contracts down & lungs retract in
explain the driving force (law) behind the air flow of ventilation
- volume & pressure
Boyles Law –> with all else constant
- increasing volume –> decrease pressure
- decrease volume –> increase pressure
how is air pulled into and out of the lungs?
- think pressures and changes in pressures
- air will go from high pressure to low pressure –> want to create a lower pressure inside the alveoli to pull the air from atmosphere into the lungs
what are the relative pressures during inspiration
atmospheric pressure: 760 mmHg (pressure 0)
alveolar pressure: due to the contraction of muscles and increasing of the space (increase volume) –> decrease the pressure inside the alveoli (approx. -1 mmHg)
** thus, air will flow from the atmosphere into the lungs (alveoli) **
what are the relative pressures during expiration
atmospheric pressure: still 760 mmHG (pressure 0)
once the lung volume has reaching max capacity –> then muscle trigger to relax and the lung wants to collapse –> this triggers a decrease in volume –> thus triggering an increase in pressure (approx. +1 mmHg)
air flows from the alveoli to the atmosphere outwards
explain the mechanism of intrapleural pressure during inspiration and expiration
intrapleural pressure is always negative
(in healthy pts. approx. -4)
during inspiration:
- pleural space gets pulled with contraction of the muscles (increasing the potential space) therefore decreasing the pressure –> MORE NEGATIVE (approx. -6)
during expiration:
- the muscles relax, the space decreases in volume and therefore the pressure increases back to its baseline
** can vary from -2 –> -6**
explain what FRC is and how it’s maintained
whats it like in inspiration? expiration?
FRC: functional residual capactiy
- the starting point for breathing –> point at which your breathe is not in or out
- at this point: the pressure gradient is maintained because the force of the chest wall wants to pull out while force of the lungs wants to pull in – keeping them at a constant
- at end inspiration: the FRC is +.5 L (500 mL)
- at end expiration: back to 0
describe the pressures within a pneumothroax
- ** pneumothorax = the intrapleural pressure is = to atmospheric pressure**
- thus you loose the vacuum created to breathe
- lungs cannot maintain expansion & collapse
- uniliateral redcued ventilation
Explain the concept of lung compliance
what are the factors
lung compliance factors
- how easy the lung can inflate
- the amount of surface tension within the air-water interface of the alveoli