Respiratory tract infection-2 (viral infections)

Question 1

Causative agent of Infectious mononucleosis

Answer 1

Epstein-barr virus

Question 2

Complication of IMN

Answer 2

Pneumonia

Pancreatitis
CNS: aseptic meningitis , encephalitis
Hemolytic anemia
Splenic rupture
Myocarditis

Question 3

Epstein-Barr virus (EBV) effect on B cell

Answer 3

Polyclonal antibodies activation and B cell Lymphoma

Question 4

Causative agent(s) of Croup syndrome

Answer 4

Parainfluenza (commonly)

Measles, Mycoplasma (less commonly)

Question 5

Symptom linked to Croup syndrome

Answer 5

Barking cough

Question 6

Common causatives of Bronchitis

Answer 6

Commonly virals (Rhino-, Corona-, Influenza-, Adeno-)

Less commonly bacterial (Mycoplasma pneumoniae, Chlamydia pneumoniae)

Question 7

Severe prolonged cough is linked to …..?

Answer 7

Bronchitis

Question 8

Common causative agent of Bronchiolitis

Answer 8

Respiratory Syncytial Virus (RSV)

Question 9

Pathophysiology of RSV

Answer 9

Infect nasopharynx and lower respiratory tract ➢

Necrosis of epithelial lining of bronchioles and peribronchial infiltration

Question 10

What antiviral is used in sever RSV cases

Answer 10

Ribavirin aerosolization

Question 11

Antiviral used in severe RSV cases

Answer 11

Ribavirin aerosolization

Question 12

What MAB used in prevention of RSV

Answer 12

Palivizumab

Question 13

Complications of influenza virus

Answer 13

• Pneumonia

• Secondary bacterial pneumonia
✓ Staph.aureus

• Myositis, pericarditis, myocarditis, Guillain-Barre Syndrome, encephalitis

• Reyes syndrome
✓ Seen with Influenza + aspirin
✓ Encephalopathy and fatty liver

Question 14

What antivirals used to treat Influenza virus

Answer 14

Zanamivir (Relenza)
oseltamivir (tamiflu)