Respiratory System - Module 10 Flashcards
Where are type 2 cells found/what do they do?
Secrete surfactant, line the alveoli.
Define total lung capacity.
The maximum amount of air that the lungs can hold (=vital air capacity + residual volume).
Define vital capacity.
The maximum amount of air that can be exhaled after maximum inhalation (=inspiratory reserve + tidal volume + expiratory reserve).
Define functional residual volume.
Amount of air still in the lungs after exhalation of that volume (=expiratory reserve + residual volume).
Define inspiratory capacity.
Max amount of air that can be inhaled after exhaling tidal volume (=tidal volume + inspiratory reserve volume).
Define residual volume.
Remaining air left in the lungs after maximum exhalation (1,200mL).
Define expiratory reserve volume.
Max amount of air that can be inhaled beyond the tidal volume (1,000mL).
Define inspiratory reserve volume.
Max amount of air that can enter the lungs in addition to tidal volume (2,500mL).
Define tidal volume.
Volume of air entering/leaving the lungs during one breath at rest (500mL).
What is a spirometer?
Device to measure lung volumes/capacities, useful in diagnosing asthma, emphysema and bronchitis.
The amount of air we inhale/exhale depends on…
- Age
- Health
- Level of activity
What is the maximum amount of air our longs can hold?
5L
What releases surfactant and when?
Released from type 2 cells during deep breathing.
Babies born before 36 weeks do not produce proper surfactant, causing alveoli to collapse. This makes it very difficult to inhale, causing infant respiratory distress syndrome.
What is surface tension?
Force developed at the surface of liquid due to attractive forces between water molecules (pull water molecules into a tight ball).
What is pulmonary emphysema?
Chronic condition produces by smokers, destroys elastin fibres. Without elastin, it is very easy to inhale but very difficult to exhale.
What is pulmonary fibrosis?
Disease that causes a decrease in compliance, caused by the constant inhalation of very fine particles. The immune cells guarding the lungs cannot destroy these particles, resulting in large amounts of inelastic collagen deposited, forming fibrous scars. Presence of scar tissue decreases compliance, making it difficult to inflate the lungs.
What are factors that influence compliance.
- Amount of elastic tissue found in the walls of the alveoli/blood vessels/bronchi.
- Surface tension of liquid lining the alveoli.
What is pulmonary compliance.
Stretchability of lungs - the more stretchable, the more compliant. Important because it determines the ease of breathing.
Low Compliance = Difficult to inflate
High Compliance = Easy to inflate but difficult to deflate.
No contraction of respiratory muscles = …
Passive process, happens during expiration.
Contraction of respiratory muscles = …
Active process, relies on signals from the respiratory center in the brainstem, happens during inspiration.
What is the pressure gradient in the lungs called and how does it assist in moving air in and out of the lungs?
Air pressure gradient
To move air INTO the lungs, it requires high pressure outside and low pressure in the alveoli.
To move air OUT OF the lungs, it requires high alveolar pressure ad low atmospheric pressure.
What is Boyle’s law of ventilation?
When the volume of a container decreases, the pressure inside increases (and vice versa).
When does pneumothorax occur?
Occurs when the intrapleural space is punctured, so no pressure is holding open the lungs (alveolar/intrapleural pressures are equal, resulting in a transpulmonary pressure of zero).
Define transpulmonary pressure.
Difference between alveolar and intrapleural pressure. This pressure holds the lungs open. In healthy lungs, the transpulmonary is positive and keeps the lungs/alveoli open.
What causes lower interpleural pressure?
The chest wall and lungs move in opposite directions.
State the mmHg for the following…
- Atmospheric pressure outside the body.
- Alveolar and atmospheric pressure.
- Pressure in interpleural space.
- 760mmHg
- 760mmHg
- 756mmHg
What is the function of the interpleural space/interpleural fluid?
Reduces friction between pleural membranes while breathing.