Respiratory system/ENT Flashcards

1
Q

Definition of asthma

A

recurrent, reversible obstruction of the airways due to inflamed bronchi

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2
Q

triggers for asthma

A

infection - eg rhinovirus especially in the winters

allergy - dust mites etc

emotions - severe emotional upset , excitement, anxiety etc

exercise - esp. running in cold air

atmosphere - dusty air, stuffy an smoke filled rooms etc

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3
Q

symptoms of asthma

A

triad of cough, SOB and wheeze
asthma should be syspected in any child with wheezing > one occasion

wheeze - exploratory high pitch wheeze, worse at night and early morning

Cough - dry, nocturnal cough usually after midnight

Chest tightness - esp with exercise and at night

SOB - establish when in exercise normally, but in severe attacks: SOB at rest, agitation, feeding difficulties and attenuated cry (infants), drowsy and confused

symptoms usually have a clear trigger and intervals in between exacerbation

strong FHX of atopy

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4
Q

what are some of the questions to be asked in suspected asthmatic patient

A

how frequent are the symptoms

what triggers the symptoms such as sport, general activities etc

how often is sleep disturbed by asthma

how severe are the interval symptoms between exacerbations?

how much school has been missed due to the illness #

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5
Q

examination findings of asthma?

A

long-standing asthmatic patients - hyperinflation of the chest/Harrison’s solci §

generalised polyphonic expiratory wheeze and prolonged expiratory phase

widespread wheeze on auscultation

harrison’s sulci possibly

evidence of eczema - atopy

growth may be affected

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6
Q

investigation of asthma

A

Usually clinical diagnosis over the age of 5 due to the present of viral wheeze

<5 yr - Diagnostic test
- treat then diagnosis after 5 yrs old

5-16 yrs
- spirometry —> BDR —> feNO

> 17 yrs follow adult diagnostic pathway

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7
Q

what are some of the differentials for asthma

A
inhalation of foreign body 
allergic rhinities 
GORD 
aspiration syndrome 
bronchiectasis 
bronchiolitis 
bronchopulmonary dysplasia 
primary cillary dyskinesia
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8
Q

chronic management of asthma for children < 5 yrs old

A

PRN SABA

Step 0 - consider monitored initiation of treatment with very low to low dose ICS

Step 1 = LTRA < 5 years

Step 2 = v low dose ICS + LTRA

Step 3 = if not adequate response from LTRA, then stop LTRA, inc dose of ICS to low dose

if benefit from LTRA then continue LTRa and inc ICS to low dose

If benefit from LTRA still, can consider ICS and LABA

Step 4 - inc ICS to mediaum dose +/- theophylline + specialist input

Step 5 - daily steriod tablet in the lowest dose + medium dose ICS

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9
Q

what are the classification of asthma in children between 2-5yrs

A
moderate asthma 
SpO2 > 92% 
able to talk 
HR <140
RR<40
severe asthma 
SpO2<92% 
too breathless to talk 
HR>140 
RR >40 
use of accessory neck muscle 
life-threatening 
SpO2 <92% 
any of the following 
1) silent chest 
2) poor respiratory effort 
3) agitation 
4) altered consciousness 
5) cyanosis
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10
Q

what are the classification of asthma in children >5 yrs

A
moderate asthma 
SpO2 >92% 
PEFR>50% 
able to talk 
HR <125 
RR < 30 
severe asthma 
SpO2 <92% 
PEFR 33-50% 
too breathless to talk 
HR >125 
RR > 30 
use of accessory talk 
life-threatening 
SpO2 <92% 
any of the following
1) silent chest 
2) PEFʀ < 33% 
3) poor resp effort 
4) agitation 
5) altered consciousness 
6) cyanosis
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11
Q

acute management for moderate asthmatic attack

A

2-10 puffs of inhaled/nebulised salbutamol not exceeding 4 hourly

one puffs every 30/60 secs to make sure not excess

consider oral prednisolone if necessary

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12
Q

acute management for severe asthmatic attack

A

2-10 puffs of inhaled/nebulised salbutamol

oral prednisone or ɪV hydrocortisone if vomiting

assess response to treatment after 15 mins

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13
Q

acute management for life-threatening asthmatic attack

A

ɴebulised salbutamol and ipratropium bromide
ɪv hydrocortisone/ɪV salbutamol if necessary
consider ɪV aminophylline/ɪV Mg

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14
Q

who does inhaled foreign body most commonly occur to?

A

Mobile toddlers who would put objects into their mouth - objects that are small enough to pass the pharynx.

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15
Q

clinical features of inhaled foreign body

A

unilateral wheeze
resp distress
asymmetrical dull on percussion if collapse occur post obstruction
hyper-resonance on percussion around the collapse area due to compensatory emphysema

most commonly occur in the R main bronchi since it is straighter than the L one

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16
Q

Ix for inhaled foreign body

A

CXR- - segmental collapse or hyperinflation seen

bronchoscopy

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17
Q

management for inhaled foregin body

A

Bronchoscopy and removal of foreign body at the same time

if complete blockage - medical emergency - Heimlich manoeuvre

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18
Q

what are the prognosis of inhaled foreign body

A

bronchiectasis occur distal to obstruction –> dilated air sac and inefficient exchange of air –> recurrent/chronic infection –> require surgical removal

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19
Q

what is ottitis media

A

inflammation and possibly infection of the media ear

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20
Q

epidem of ottitis media

A

most frequent up to 7yrs
2.5-5yrs most common
most children will have an episode of OM but some 20% will have at least 3 episodes

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21
Q

Aetiology of Ottitis Media in children

A

children have a much shorter, more horizontal and poorly functioned Eustachian tube and so the drainage of the middle ear is not as good as in adult

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22
Q

causes of Ottitis media

A

virus - RSV, rhinoviruses

bacterial - strep pneumonae, haem. influenzae

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23
Q

what condition predisopse children with dysfunction Eustachian tube?

A

Down’s
post- common cold
adenoidal hypertrophy
cleft palate

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24
Q

clinical features of Ottitis Media

A

fever
painful ears
hearing loss
Preceded by URTI

younger children - anorexia, vomiting + diarrhoea

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25
Q

what examination must you carry out if a child has a fever

A

exam of the tympanic membrane for ottitis media

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26
Q

what are the exam finding of ottitis media

A

inflamed tympanic membrane
bulging tympanic membrane
loss of light reflex

perfusion of eardrum along with pus present

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27
Q

management of ottitis media

A

many causes are viral - supportive and should resolve in time

delayed Amoxicillin prescription - give the prescription to the parents but ask them only to get the medication after 2-3 days if not better - ABx only indicative if children >6mnths old and symptoms persist > 48 hrs

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28
Q

prognosis of ottitis media

A

most cases resolve fine

some might have recurrent infection and have ottitis media with effusion, more severe - mastoiditis, meningitis

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29
Q

what is ottitis media with effusion

A

glue ear - recurrent ottitis media leading to exudate production and and building up pushing against the eardrum and so conductive hearing loss

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30
Q

exam finding of OME

A

tympanic membrane thicken, retarted, absent light reflex

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31
Q

IX for OME

A

flat trace of tympanometry and conductive hearing loss

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32
Q

management of OME

A

if significant hearing loss - insert ventilation tube ( grammets)

if fluid still persist - insert another grammet (might be blocked) + consideration of adenoidectomy (long term benefit)

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33
Q

what are some of the causes of resp failure in children

A
lower airway obstruction 
Upper airway obstruction 
cardiac 
neurological 
toxic allergy
34
Q

signs and symptoms of resp failure

A
dyspnoea
tachypnoea
cyanosis 
nasal flaring 
subcostal, intercostal recession 
tracheal tug 
grunting in baby
head bobing in baby 
wheeze - maybe quiet if wheeze caused by asthma
restless, agitation
impaired consciousness and confusion
35
Q

causes of lower airway obstruction RF

A
asthma 
bronchiolitis 
pneumonia 
cystic fibrosis 
neonatal lung disease
36
Q

causes of upper airway obstruction RF

A

inhaled foreign body
croup
epiglottitis

37
Q

causes of cardiac RF

A

severe HF

38
Q

management of RF

A

If cyanosed/hypoxic, but PaCo2 normal then give O2 support aiming for 92% - be mindful of re-perfusion injury

If hypoxic and raised PaCO2, then this is a sign of lack of ability to self ventilate which means it is now time for some external ventilation support

treat underlying causes - ABx, steroids, bronchiodilator for asthma, bronchoscopy for foreign body

39
Q

what is stridor

A

it is a symptom - loud, harsh, high pitched sound usually heard on expiatory breathing, but in severe cases of upper airway obstruction eg trachea and bronchial obstruction, it can occur in inspiratory

40
Q

what are the emergency causes of stridor

A

inhaled foreign body
croup
epiglottitis

41
Q

what are some of the common cuases of stridor

A
laryngomalacia 
subglottitis stenosis
epiglottis 
croup 
inhaled of foreign body
42
Q

what does biphasic stridor usually suggest in children

A

subglottitis/glottitic obstruction

43
Q

What is the different between asthma and viral wheeler induced wheeze

A

Viral induced wheeze usually Preston in 1-5 yrs caused by virus - no symptoms when well

Asthma - wheeze and SOB and continue when symptoms continue even when well

44
Q

what is the chronic management of asthma for a child who is > 5 yrs old

A

step 0 = PRN SABA

Step 1 = v.low dose of ICS

Step 2 = V.low dose of ICS + inhaled LAMA

Step 3 = if LAMA not beneficial then stop and inc dose of ICS to low dose

if LAMA beneficial then continue and inc dose of ICS to low dose

If LAMA beneficial then continue + inc dose of ICS to low dose + consider adding in LTRA

Step 4 = inc ICS dose to medium dose + inhaled LAMA + LTRA + theophylline + specialist input

Step 5 = daily oral steroid tablet + inhaled medium dose of ICS + specailist inout

45
Q

What is bronchiolitis

A

It is a viral infection of the small bronchioles which in adults do not commonly cause any problems but in children with small bronchioles, they cause restriction too small that it will stop the breathing of the child

46
Q

What is the common affected age group of bronchiolitis?

A

< 18 months

47
Q

What are the common pathogens that cause bronchiolitis?

A

Respiratory syncytial virus (75%) - epidemics in winter

Parainfluenza virus, adenovirus, influenza, rhinovirus

Mycoplasma pneumoniae

48
Q

Clinical features of bronchiolitis?

A
Wheeze, cough
Rhinitis 
Signs of resp distress if severe - eg recession, nasal flaring, tachypnoea
Overexpression of lung, fine crackles 
Fever
49
Q

What are the investigation for bronchiolitis

A

Usually clinical diagnosis
Oximeter
CXR - if severe and chronic CHD and respiratory problem suspected - shows over-inflated, collapse, consolidation if severe

50
Q

Management of bronchiolitis

A

Usually supportive
If feeding okay at home
If resp distress, hospital admission

51
Q

What is bronchiolitis called after 18 months

A

Viral wheeze

52
Q

What can be give to infant who have chronic resp problem and CHD?

A

Palivizumab - monoclonal antibodies against RSV

53
Q

What is another name for croup?

A

Acute laryngotracheobronchitis

54
Q

What is the most common pathogen that causes croup

A

Parainfluenza virus

Other also incl RSVm, adenovirus, influenza A/B

55
Q

What is the most common age for croup

A

6 months - 2/3 years

56
Q

Symptoms of croup?

A
Croyza 
Fever 
Stridor 
Seal-like barking cough 
Hoarseness (esp on crying) 
Wheeze 
Tachypnoea 

Symptoms worse at night
IWOB
Cyanosis if severe
Restlessness

57
Q

What causes the seal-like symptoms?

A

Caused by the inflammation of the subglottic region which causes airflow turbulence so high pitch

58
Q

Investigation for croup?

A

Clinical diagnosis

CXR not needed (but if done, will show the steeple sign)

59
Q

What is a steeple sign

A

Wine bottle signs which is specialised in croup (where the subglottis region is swollen)

60
Q

Management of croup

A

Most cases will only need supportive management

However, if swelling persist then oral dexamethasone (0.15mg/kg)

Oral prednisolone is alternative

For severe cases, neb adrenaline can be used to acutely reduce inflammation

61
Q

What is epiglottis

A

It is cellulitis of the supra-glottis region which can potentially cause airway obstruction

Can be life-threatening, considered to be emergency

62
Q

What is the most common causative pathogen for epiglottis

A

It is haemophilia influenza B (although it should be rare nowadays due to vaccination against HIB)

Other common curative agent —> parainfluenza, Staph aureus, strep pneumoniae, MRSA, Candida (rare)

63
Q

What is the most common age group that presents with epiglottitis

A

Age 2-4 (age group just after croup which can present just like epiglottitis)

64
Q

What is the symptoms of epiglottitis

A

3Ds

Drooling, dysphasia, distress

Sore-throat, hot potato voice

Inability to swallow

Irritable/restless

65
Q

What should you not do in epiglottitis

A

Do not examine the mouth/throat, you might just cause obstruction which means airway loss

66
Q

What are the examination findings of epiglottitis

A

Stridor (inspiratory noises)
Tripod position/recession
Tachycardia
Tachypnoea

67
Q

Investigation for epiglottitis?

A

If done at all

Gold standard - nasal laryngoscopes

Lateral neck X-ray - thrums signs (epiglottis thickening)

Throat swab (after airway secure with intubation)

Blood culture (if systemically unwell)

68
Q

Management of epiglottitis

A

Protect airway - intubation, may need a cricothyroidectomhy

IV cefotaxime or ceftriaxone

Humidified O2

Can use dexamethasone to further reduce inflammation of the epiglottis

Can use neb adrenaline to manage acute closure

69
Q

What is the prognosis of epiglottitis

A

If able to intubation and treat with IV cefotaxime or ceftriaxone = excellent outcome

If not, then death or severe brain injury from hypoxia

70
Q

What are the most common pathogens that causes pneumonia in neonates?

A

Group B strep, E.coli, klebisella, staph. Aureus

71
Q

What are the most common pathogens that causes pneumonia in infant?

A

Strep pneumonia, chlamydia

72
Q

What are the most common pathogens that causes pneumonia in school age?

A

Strep pneumoniae, staph aureus, group A step, bordetella pertussis, mycoplasma pneumoniae

73
Q

What are some of the viral causes to pneumonia?

A
RSV
Parainfluenza 
Influenza 
Adenovirus 
Coxsackie virus (coxsackie A —> Hand, for, mouth disease
74
Q

What predispose children to pneumonia

A
Chronic lung disease 
CF 
CHD 
Immunodeficiency 
Tracheotomy in situ 
Inhaled foreign body
75
Q

Symptoms & signs of pneumonia in neonates?

A
Grunting 
Recession 
Cyanosis 
Cough poor feeding 
Irritable 
Fever
76
Q

Symptoms & signs of pneumonia in infant

A
Cough, grunting, recession
Fever 
Wheezy 
Preceded by URTI 
Irritable 
Feeding difficulties 
Tachypnoea
77
Q

Symptoms & signs of pneumonia in pre-school/older children?

A

Cough
Tripod position
Fever
Preceded by URTI
Pain (chest/abdo - lower lobe infection irritates the abdo area)
Post-tussive vomiting - post cough vomiting)

78
Q

Investigation of pneumonia in children

A
FBC - WCC raised 
CRP - raised 
Sputum culture - in older children only 
Blood culture - if severe 
CXR - focal - bacterial / diffuse - viral 

Skin tuberculin test - test for TB
Cold agglutinis - mycoplasma pneumoniae (atypical pneumonia)

79
Q

Management of pneumonia

A

Supportive

Anti-pyrexia - avoid aspirin due toe danger of Reye’s syndrome

Admission to hospital - usually okay to management in community, but if resp distress, poor feeding, tachycardia, raised CRT, chronic lung disease etc then admit

ABx - can’t differentiate between viral and bacterial if high fever then usually bacterial then consider ABx

Acute - IV penicillin
Sub-acute - PO amoxicillin
If allergic - clarithromycin, erythromycin

80
Q

Prognosis/complications of pneumonia

A

Prognosis usually good

Complications

Lung abscess 
Emphysema 
Pneumothorax 
Septicaemia 
Bronchiectasis 
Pleural effusion