Respiratory system Flashcards
Inspiration:
Diaphragm contracts/ flattens/ moves downwards
Intercostal muscles contract to move ribs up/out
Increase volume of thorax
Reduce pressure of thorax below atm pressure/ pressure gradient (-ve)
Adaptation of lungs:
Many alveoli - more s.a. for CO2/ O2 to diffuse
Epithelium of alveoli is very thin - short diffusion distance
Capillaries running over surface of alveoli - delivers CO2 (to be removed from blood)/carries O2 away (from alveoli)
Lungs surrounded by diaphragm/ icm- ventilation/ supply of O2/ removal of CO2
1 volume, inside/ of, jar increases ;
2 pressure inside, jar/ balloons, decreases;
3 to below pressure in atmosphere; [idea of creating a pressure gradient (between balloon and exterior)// Note: ‘makes pressure in jar lower than atmosphere’ = 2 marks]
4 (therefore) air, moves/ pushed/ forced, into, balloons/
glass tube; [flows / enter / fills]
Define tidal volume: (2mks) [f211 june14 q2bi]
1) volume of air, inhaled/ exhaled; [breathed / moved, in (and / or out of lungs)]
2) in, one/ each, breath;
3) during, steady/ regular, breathing; [at rest / during steady exercise / normal / quiet breathing]
Suggest how the bell-jar model may be used to demonstrate tidal volume: [f211 june14 q2bii]
1) up/ down, movements (of rubber sheet / band); [pull / push on rubber sheet / band // pull / push and let go]
2) small/ steady/ regular, movements (of rubber sheet); [rhythmically / in time with breathing / repetitively // Note: pulled down slightly = 2 marks]
Define vital capacity: [f211 june14 q2biii]
1) the maximum volume of air; [tidal volume + inspiratory reserve + expiratory reserve = 2 // total lung capacity – residual volume = 1 mark]
2) inhaled/ exhaled, in one breath; [breathed, in / out, in one breath]
Suggest how the bell-jar model may be used to demonstrate vital capacity: [f211 june14 q2biv]
pull down on rubber, sheet/ band, as far as possible and pushed up as far as possible [pull / push in either order // pull and push as hard as possible]
Role of squamous epithelium in lungs: [f211 june13 q2c]
short(er) diffusion, distance / path ; [reduced / shorter diffusion distance// thin diffusion barrier]
Role of large no of alveoli in lungs: [f211 june13 q2c]
large(r) surface area ; [increases surface area// (do NOT ref to sa : vol ratio) ]
Role of good supply of blood in lungs: [f211 june13 q2c]
high / large / steep, concentration gradient
OR removes oxygen (from lung surface) / brings carbon
dioxide (to lung surface); [maintains / creates concentration gradient// do NOT ref to diffusion grad.) ]
Role of good ventilation in lungs: [f211 june13 q2c]
high/ large/ steep, concentration gradient OR supplies oxygen (to alveoli)/ removes carbon dioxide
(from alveoli) ; [maintains/ creates concentration gradient]
Explain what causes the change in the volume of air
between point B and C on Fig5.1 (during expiration):
(4mks) f211 jun12 q5b
1 (external) intercostal muscles / diaphragm, relax ; [ref to internal intercostal muscles contracting]
2 rib cage / ribs, move down OR diaphragm, moves /
pushed, up ;
3 volume of, thorax / chest cavity / lungs, drops /
decreases ; [‘space inside’ or ‘air in’ for volume]
4 pressure inside, thorax / chest cavity / lungs, increases ;
5 above, external / atmospheric, pressure ; [(pressure) higher than outside]
6 air leaves down pressure gradient ;
7 (elastic) recoil of alveoli ;
Suggest why it is not possible to expel all the air from the lungs (tidal volume): (2ks) f211 jun12 q5d
1 thorax / rib cage / lungs, cannot be completely, compressed/ flattened;
2 trachea/ bronchi, held open by cartilage;
3 bronchioles/ alveoli, held open by elastic fibres;
4 [absence of pressure gradient/ atmospheric and thoracic pressure equal// presence of surfactant in alveoli// upward movement of diaphragm limited collagen fibres]
Using the mammalian gaseous exchange system as an example, explain how the different cells and tissues enable the effective exchange of gases. (5mks) [f211 june11 1c]
C1 thin / squamous, epithelium;
C2 thin endothelium (of capillary);
F1 (provides) short diffusion distance; [diffusion barrier , thin / one cell thick]
F2 ref to surfactant (from epithelial cells), reducing surface tension/ preventing alveoli collapsing;
C3 blood/ red blood cells/ erythrocytes; [blood supply/ supply of blood]
F3 transports (named) gas(es), to/ from, exchange surface/ alveoli;
C4 diaphragm/ intercostals, muscles;
F4 (maintains/ creates) diffusion/ concentration, gradient;
C5 ciliated epithelium/ goblet cells/ ciliated cells;
F5 idea of: protection from/ removal of, dust/ bacteria/ pollen/ spores; [trap, dust/ bacteria/ pollen/ spores]
C6 cartilage;
F6 hold airway open;
C7 smooth muscle;
F7 constrict/ control diameter of, airway/ blood vessel; [narrows lumen]
C8 elastic, fibres/ tissue;
F8 for recoil/ aiding ventilation; [prevent alveoli bursting]
C9 macrophage/ neutrophil;
F9 engulf/ destroy pathogens or protect from infection;
{{different q: many alveoli to produce large SA; barrier, thin/ only 2 cells thick; good blood supply/ many capillaries; to carry dissolved gases to and from the alveoli; ventilation to refresh the air in alveoli; contains elastic tissue to stretch and recoil to help expel air}}
Describe how the spirometer would be used to measure tidal volume. (3mks) [june11 5ai]
1 idea of not breathing through nose ; [e.g. subject wears nose clip / plug or holds nose]
2 subject breathes , evenly / normally / regularly ;
3 idea of (measure) height / amplitude , of waves
(from trace) ; [(measure) difference between peak
and trough]
4 measure at least three waves and calculate mean ;
5 detail of how spirometer works ; [e.g. as breathe in lid goes down / as breathe out lid goes up; e.g. movement of lid recorded , on trace / by data logger
e.g. pen attached to lid moves up/down as breathe;
DO NOT CREDIT description of water level
changing IGNORE ref to using mouthpiece, soda lime,
oxygen]