Respiratory System Flashcards
Diaphragm
primary muscle of respiration
Diaphragmatic Hernia
GI organs migrate into the thoracic cavity through a hole in the diaphragm
Dx: no heart sounds on 1 side of chest or may hear gut sounds
Tx: sx - must use ventilator
Spinal Cord Injuries
Can’t use phrenic nerve - innervates the diaphragm
Pleura
lined with simple squamous epithelium
Functions: reduces friction and releases mucus
Parietal
lines the thoracic wall
Visceral
lies the organs within the thoracic cavity
Mediastinum
barrier between right and left lungs
prevents both lungs from collapse and infection
Intrapleural space
necessary to inflate lungs
negative pressure, vacuum, no air
should never have anything in it
Trachea/Bronchial Tree
Airway
O2 inhaled/CO2 exhaled
Aspiration Pneumonia
Inflammation of the lungs caused by inhalation of foreign substances
Right Lung Lobes
Right Cranial Lung Lobe
Right Middle Lung Lobe
Right Caudal Lung Lobe
Right Accessory Lung Lobe
Left Lung Lobes
Cranial Part of the Left Cranial Lung Lobe
Caudal Part of the Left Cranial Lung Lobe
Caudal Lung Lobe
Bronchioles
Lined with smooth muscle
Involuntary
Bronchodilation
Relaxation of the bronchioles
Bronchoconstriction
Contraction of the bronchioles
Alveolar Sacs
Lined with simple squamous epithelium
Surrounded by yellow elastic connective tissue
Gas exchange occurs
Emphysema
A condition in which the alveolar sacs are damaged resulting in a decrease in pulmonary compliance
Tx: oxygen therapy - only adds O2 to system, does not help flush out expired CO2
Inhalaltion
Active process
Contraction of muscles - intercostal
Diaphragm is pulled caudally
Exhalation
Passive process
Muscles relax
Diaphragm is pulled cranially
Composition of air
O2 = 21% N2 = 79% CO2 = <1% (300ppm)
Acid/Base Balance
pH of blood - 7.4 +/- 0.02
Decrease CO2
2 organs involved - lungs and kidneys
Acid/Base Balance - Lungs
CO2 increased
decreased pH
K+ in blood
Acid/Base Balance - Kidneys
Increased H2CO3 (carbonic acid)
K+ in blood
Decreased HR
Pneumotaxic center
Measures CO2 levels
- increase CO2 = increase respiration
Tidal Volume
Formula: 10-15ml/kg
Amount of air contained in one entire breath (inhalation and expiration)
Minute Volume
Formula: Tidal volume x RR
Amount of air contained in one minutes worth of breathing
Gas Exchange - Capillary
Low in O2
- pO2: 40 mmHg
High in CO2
- pCO2: 46 mmHg
Gas Exchange - Alveoli
High in O2 - pO2: 100 mmHg Low in CO2 - pCO2: 40 mmHg Termed ETCO2 (End Tidal CO2) - partial pressure of CO2 at the end of an exhaled breath - normal: 35-45mmHg
Capnography
monitoring the concentration or partial pressure of CO2 in respirator gases 3 values - RR: 15-30 rpm - ETCO2: 35-45 mmHg - InCO2: 0-5 mmHg (inspiratory CO2)
Gas Transport - Oxygen
Almost all bound to hemoglobin in RBCs
Small amount in plasma
Arterial blood - 97%
Venous blood - 70%
Pulse Oximetry
% of Hb saturated with oxygen
- SpO2: saturated Hb with O2
Gas Exchange - Carbon Dioxide
10% dissolved in plasma
20% combined with hemoglobin
70% transported as an ion
Respiratory Alkalosis
Decreased CO2, Decreased H2CO3, Increased pH
Caused by:
- Hyperventilation
- Iatrogenically during anesthesia
Respiratory Acidosis
Increased CO2, Increased H2CO3, Decreased pH, Increased K+, Decreased HR 3 Types: - Intrapleural - Intraalveolar - Misc
Intrapleural Causes of Respiratory Acidosis
AKA: atelectasis
Something extra in the pleural space
Pneumothorax
Presence of free air in the thorax
Pyothorax
Presence of pus in the thorax
Hemothorax
Presence of blood in the thorax
Chylothorax
Presence of lymphatic fluid in the thorax
Pneumonia
Lower respiratory infection - alveoli
Drowning
Presence of H2O in the alveoli
Pulmonary Contusion
Bruising of the lung caused by chest trauma
Pulmonary Edema
Build up of fluid in the alveolar sacs
Intraalveolar Causes of Respiratory Acidosis
Anything which causes no gas exchange Ex: - Drowning - Pneumonia - Pulmonary Contusion - Pulmonary Edema
Misc Causes of Respiratory Acidosis
- Emphysema
- Obstructed airway
- Asphyxiation
Emphysema
Lungs lose elasticity
Obstructed Airway
Aspiration
Strangulation
Mucus plug in ET tube
Medications
Asphyxiation
Closed space
Anesthesia machine
Why do we ventilate a pt on anesthesia?
To decrease excess CO2 - prevent hypercapnia
To prevent atelelectasis
4 Elements of Blood Gas
pH: 7.35-7.45
pCO2: 35-45 mmHg
HCO3: 18-25 mmol/L
Anion gap: 12-24 meq/l
Acid/Base Balance - Formula
CO2 + H20 H2CO3 H + HCO3
Metabolic Acidosis
Low pH
Low HCO3
Causes: renal failure, ketoacidosis
Metabolic Alkalosis
High pH
High HCO3
Causes: vomiting, decrease in HCl
Respiratory Acidosis
Low pH
High pCO2
High HCO3 - tries to neutralize acid
Causes: neurological, respiratory, paralysis
Respiratory Alkalosis
High pH
Low pCO2
Low HCO3 - kidneys excrete bicarbonate
Causes: excessive ventilation
Functions of Blood
Transportation of O2, CO2, nutrients, hormones, vitamins, waste
Regulation of pH, fluid balance, body temp
Defense against foreign organisms
Plasma
Fluid portion of anticoagulated blood
Serum
Fluid portion of coagulated blood
Dissolved Substances of Blood
Proteins - albumin, clotting factors, antibodies
Nutrients - glucose, oxygen
Electrolytes - Na+, Cl-, K+
Waste Products - BUN, bilirubin
Hormones and Enzymes - insulin, acetylcholinesterase
Pericardial Sac
Membrane
Dense fibrous connective tissue
Function: reduces and prevents friction
Epicardium
Simple squamous epithelial tissue
Function: reduces friction
Myocardium
Cardiac muscle
Function: pumps blood
Endocardium
Simple squamous epithelial tissue
Function: prevents blood from clotting in chambers
Medial Septum
Cardiac muscle
Divides R & L sides of the heart
Right Atrial-Ventricular Valve
Tricuspid
Separates R atria and R ventricle
Left Atrial-Ventricular Valve
Bicuspid
Separates L atria and L ventricle
Aortic Valve
Located at opening of aorta
Pulmonic Valve
Located at opening of pulmonary artery
Electrical Conduction System
SA node
AV node
Bundle of His
Purkinje Fibers
Diastole
Relaxation of ventricles
Systole
Contraction of ventricles
Cardiac Output Formula
Stroke volume X heart rate
Systolic Pressure
100-160 mmHg
Diastolic Pressure
60-100 mmHg
Mean Arterial Pressure
80-120 mmHg
Right Heart Failure (RHF)
Blood will back into vena cava and then to abdominal cavity
Symptom: ascites
Left Heart Failure (LHF)
aka: Congestive Heart Failure (CHF)
Symptom: pulmonary edema, decreased BP due to tachycardia
Treatment: O2, diuretic, cardiac regulator
Electrocardiogram (ECG)
Helps diagnose arrhythmias
Shows electrical activity of the heart
Leads for ECG
White - right axillary Black - left axillary Red - left inguinal Green - right inguinal Tan - sternum
5 Parts to an ECG
P wave - atrial depolarization
QRS Complex - ventricular depolarization
T wave - ventricular repolarization
Respiratory Sinus Arrhythmia
Can be a normal variation in dogs
HR will increase on inhalation and decrease on exhalation
Ventricular Premature Contraction (VPC)
Some ectopic force is causing ventricle to beat prematurely
Okay if occasional
Treatment: lidocaine and prcainamide
Ventricular Tachycardia
More than 3 VPC’s in consecutive sessions
Results in significant decrease on C.O.
Treatment: lidocaine and procainamide
Ventricular Fibrillation (V fib)
Ventricle is not contracting in a normal fashion
Only Treatment: defibrillation
Second Degree AV Block
There is a block in conduction between the SA node and the AV node
Will result in bradycardia
Treatment: anticholinergics, atropine sulfate
Third Degree AV Block
SA and AV node are not communicating
P wave and QRS complex are not coordinated
Treatment: peacemaker
Parasympathetic
decreased HR
Sympathetic
increased HR
Epinephrine
sympathetic
chronotropic
speeds up HR
Cortisol
stress hormone
adrenal cortex
increased contractility
increased HR