Respiratory Physiology III: Pulmonary Gas Exchange (Exam 4) Flashcards

1
Q

Blood coming into the capillaries (before diffusion) through the pulmonary artery:

PO2:
PCO2:

A

PO2: 40mmHg
PCO2: 45 mmHg

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2
Q

In the alveoli:

PAO2:
PACO2:

A

PAO2: 100mmHg
PACO2: 40mmHg

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3
Q

Blood exiting the capillaries (after diffusion) through the pulmonary vein:

PO2:
PCO2:

A

PO2: 100mmHg
PCO2: 40mmHg

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4
Q

When blood reaches the pulmonary vein, the PO2 and PCO2 have reached:

A

equilibrium

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5
Q

When blood enters the left heart, the PO2 is actually at ____. This is due to ___.

A

PO2= 95mmHg

This is due to bronchial circulation

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6
Q

To calculate a partial pressure, you must determine the ____ of the gas to other molecules

A

relative concentration

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7
Q

Refers to the pressures of one gas in a mixture of gases

A

partial pressure (Pgas)

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8
Q

Equation for partial pressure of a gas:

A

Pgas= PATM x fractional concentration of gas

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9
Q

The atmospheric pressure (PATM) at sea level is ____ and air is composed of ____.

A

760mmHg; 79% nitrogen & 21% oxygen

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10
Q

Fraction of inspired oxygen:

A

FiO2

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11
Q

Calculate the partial pressure of oxygen in our atmosphere:

A

PO2= 760 x 0.21 = 160mmHg

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12
Q

As air passes through the conducting zone of the lung, it is humidified creating:

A

a partial vapor pressure for water

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13
Q

As air passes through the conducting zone of the lung, it is humidified creating a partial (vapor) pressure for water (PH2O = 47mmHg). This addition of water does what to the partial pressure of oxygen?

A

decreases

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14
Q

Calculate the partial pressure of oxygen with the addition of the partial vapor pressure of water at 47mmHg

A

PO2= (760mmHg - 47mmHg) x 0.21 = 149mmHg

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15
Q

At normal alveolar ventilation and O2 absorption rates (250ml/min), PAO2 is:

A

100mmHg

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16
Q

Increasing alveolar ventilation will ____ PAO2

A

increase

17
Q

Equation for alveolar ventilation:

A

Alveolar ventilation = (TV-DS) x RR

18
Q

According to the equation:

Alveolar ventilation = (TV-DS) x RR, you can increase alveolar ventilation by:

A

increasing TV or RR

19
Q

A gas within a liquid also exerts a _____.

A

partial pressure

20
Q

To calculate a partial pressure in a liquid solution, the ____ and the ____ of the gas are required

A

relative concentration; and solubility coefficient

21
Q

Attractability of molecules to water:

A

solubility coefficient

22
Q

If the solubility coefficient number is high:

A

the gas diffuses in the liquid quickly

23
Q

Henry’s Law:

A

Partial pressure = (concentration of dissolved gas) / (solubility coefficient)

24
Q

Concentration of dissolved gas equation: (rearrangement of henry’s law)

A

Conc. of dissolved gas= solubility coefficient x partial pressure

25
Q

At a constant temp, the amount of a gas that dissolve in liquid id _____ to the partial pressure and solubility

A

directly proportional

26
Q

Compare the solubility of CO2 to O2:

A

CO2 is more soluble than O2

27
Q

Why would a patient who has trouble oxygenating their blood be able to transport & get rid of CO2 more easily?

A

Because CO2 is more soluble

28
Q

The higher the partial pressure of the gas, the ____ we will be able to dissolve into the liquid

A

more

29
Q

Gas exchange at the respiratory membrane depends on:

A
  1. transport rate through the respiratory membrane
  2. The rate of alveolar ventilation
30
Q

An increase in alveolar ventilation will ___ PAO2 and gas exchange with an upper limit of ____ which is ____.

A

increase; 149mmHg; the PAO2 of humidified air

31
Q

The rate of alveolar ventilation has upper limit of 149mmHg. Describe a scenario where this limit might surpassed:

A

Patients that are on oxygen may have higher FiO2 (fraction of inspired oxygen) than 21% which would increase the partial pressure of oxygen