Respiratory Physiology Flashcards
CO + Hgb
Carboxyhemoglobin
CO2 + Hgb
Carbaminohemoglobin
low ARTERIAL pO2
Hypoxemia
low TISSUE p02
Hypoxia
Principal buffer in the interstitial fluid
Carbonic Acid (via carbonic acid-bicarbonate system)
Unloading of CO2 to lungs
HALDANE EFFECT
Unloading of O2 to tissues
BOHR EFFECT
Shift to R of 2 Dissociation curve
Slow Reactive Substances of Anaphylaxis (SRS-A)
LTC4, D4, E4 (Leukotrienes)
Decreased by steroids in ASTHMA to decrease bronchoconstriction!
Where V/Q is ZERO
Shunt (R to L, obstruction)
Where V/Q is infinite
Pulmonary embolism
LOW VQ means
Low ventilation
High perfusion
Creates Basic Respiratory Rhythm
Medulla (DRG, VRG (exercise)- Respiratory Center)
Modifies Basic Respiratory RHYTHM
Pons
UP Pneumotaxic - pneumonia - bilis hinga
DOWN Apneustic Centers - apnea - bagal hinga
Type of hypoxia in CO poisioning
ANEMIC HYPOXIA