Phase 1 Exam Flashcards
EPO is secreted from:
PERITUBULAR CAPILLARIES from cortical nephrons
Function of Vasa Recta
COUNTERCURRENT EXCHANGER - maintains concentration gradient
PODOCYTES are also known as:
VISCERAL EPITHELIUM
BOWMAN’s CAPSULE is also known as:
PARIETAL EPITHELIUM
Cell found in the renal corpuscle which is modified
smooth muscle capable of phagocytosis
Mesangial Cell
INTRA and EXTRA Glomerular
Farmer turned soldier
Formula for renal clearance
C = UV/P
U = urine conc V = urine vol P = plasma conc
Effect of Angiotensin II
vasoDILATE AFFerent arteriole
Effect of Nitric Oxide in Kidney
vasoCONStrict EFFerent arteriole
Effect of Adenosine
vasoCONstrict AFFerent arteriole
Which solute is mainly reabsorbed in the thick ascending limb (TAL) of LH?
Magnesium
(PASAWAY)
Other solutes are reabsorbed in PCT
Action of ANP and BNP in kidney
INHIBIT Na reABSORPtion
A - atrium
B - Bentricles
Counters Aldosterone (stimulates Na reabsorption)
Gain of acids (Metabolic Acidosis)
HAGMA
Loss of Bases
Metabolic Acidosis
NAGMA
What is the active form of Vitamin D?
CALCITRIOL
AuerBACH Plexus is also called?
MYEnteric Plexus
MOTILITY
A-M-M
MEISsner Plexus is also called?
SubMUCOsal Plexus
SECRETION
M-S-S
GI PHYSIO
TRIGGER: CHON and aa (esp. F, W, M),
Gastric Distention
SOURCE: G cells of the ANTRUM
ACTIONS: Stimulates Parietal cells in
FUNDUS for HCl Secretion
(G for) GASTRIN
GI PHYSIO
TRIGGER: H+ in the duodenum, FA in
duodenum
SOURCE: S cells in the duodenum
ACTIONS: Inhibits HCl secretion, increases
biliary and panc. HCO3-
SECRETIN
*this hormone does NOT affect pancreatic
ENZYME secretion!
Meaning of GIP
Glucose-dependent Insulinotoropic Peptide
Stimulates insulin secretion
Secreted by K cells in duodenum
Damage to this area in the hypothalamus will cause
weight gain
VentroMedial
VUTSOG - SATIETY Center
vs
Lateral - Lamon - Hunger center
What is the GI pacemaker?
Interstitial cells of Cajal
SLOW WAVES
Slowest - Stomach
Fastest - Duodenum
Empty into the intestinal glands, secrete an alkaline fluid composed of mucin, which exerts a physiologic ANTI-ACID function by coating the duodenal epithelium, therefore protecting it from the acid chyme of the stomach.
BRUNNER GLAND secretions
Essential secretion of stomach
INTRINSIC Factor (IF)
X Vit B12
X DNA Formation
GI Physio
Contains:
Mucus Neck Cells
Parietal Cells
Chief Cells
Oxyntic GLANDS (Body)
GI Physio
Contains:
G Cells
Mucus Cells
PYLORIC Glands (Antrum)
GI Physio
Contains:
Mucus
HCO3
Mucus Cells
Mucus Neck Cells
GI Physio
Contains:
HCl
IF
PARIETAL cells
GI Physio
Contains:
Gastrin
G cells
GI Physio
Contains:
Serotonin
enteroCHROMAFFIN Cells
The OG Boss
GI Physio
Contains:
Histamine
enterochromafiin-LIKE Cells
The gaya gaya - histamine
GI Physio
Contains:
Chief/Peptic Cells
PEPSInogen
ChiefPEP
Active component of bile?
GLYCO-deoxy-cholic
TAURO-deoxy-cholic
GLYCO-litho-cholic
TAURO-litho-cholic
ACIDS
Let’s emulsify knowledge!
The only monosaccharides
GLUcose
GALACtose
FRUctose
Difference of BILIRUBIN and BILE SALTS
BILE SALTS - emulsification of fats
BILIRUBIN - breakdown of heme
Most common 2nd messenger system
cAMP
Oxytocin is produced from?
PARAventricular NUCLEI of ANTERIOR Hypothalamus
Vasopressin (ADH) is produced from?
SUPERIOR OPTIC NUCLEI of ANTERIOR Hypothalamus
The Anterior Pituitary produces what?
[BASOPHILIC] "BFLAT" F-SH L-H A-CTH T-SH M-SH
[ACIDOPHILIC]
GH
PROLACTIN
TRUE or FALSE
PTH have direct effect on small intestines.`
FALSE
Function of PTH
Inc CALCIUM
(Gustong-gusto talaga ni PTH ang Calcium na willing siya mawala si PHOSPHATE!)
PHOSPHATE-TRASHING HORMONE
PRODUCE sperm
Seminiferous tubules
Mother
MATURES sperm
EPIDIDYMIS
School
STORES sperm
VAS DEFERENS
House
SUPPLIES sperm with NUTRIENTS
Seminal Vesicle
Father-supplier-store
ALKALINIZE sperm
PROSTATE GLAND
via 5-alpha reductase
Testosterone –> DHT
(Coach)
Main form of estrogen during REPRODUCTIVE YEARS
estraDIOL
wifey & hubby
Main form of estrogen during PREGNANCY
estraTRIOL
wifey, hubby. & baby
Main form of estrogen during POST-MENOPAUSAL years
estrONE
wifey na lang
HEMA PHYSIO
Synthesis of Hgb starts
P RO
[erythroblast]
PBPORE
HEMA PHYSIO
NuclEOLI disappear
B ASOphilic [erythroblast]
PBPORE
HEMA PHYSIO
Hgb disappears
P OLYchromatic [erythroblast]
PBPORE
HEMA PHYSIO
Nucleus disappears
O RTHOchromatic [erythroblast]
PBPORE
HEMA PHYSIO
Stage that enters blood
P OLYchromatic [erythroCYTE]
PBPORE
Granulocytes
Baso
Eosino
Neutro (highly lobulated)
Smallest antibody
IgG
Antibody that can enter placenta
IgG (kasi smallest)
Largest antibody
IgM
Antibody found in human secretions (saliva, Peyer’s, milk)
IgA
The first step in hemostasis is caused by
Endothelin-1
Local myogenic spasm
Factor III
Tissue Factor (extrinsic)
Factor VII
Hageman Factor (intrinsic)