Respiratory Pharm Flashcards

1
Q

Bronchodilator Classes

A

beta 2 agonists and anticholinergics

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2
Q

Long acting bronchodilators

A

Salmeterol
Formoterol
Tiotropium

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3
Q

Short acting bronchodilators

A

Albuterol(Proventil)
Levalbuterol(Xopenex)
Ipratropium(Atrovent)

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4
Q

Anticholinergic bronchodilators

A

Ipratropium(Atrovent)
Tiotropium

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5
Q

Beta2 agonist bronchodilators

A

Albuterol(Proventil)
Levalbuterol(xopenex)
Salmeterol
Formoterol

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6
Q

Oral Corticosteroids

A

For short term exacerbations
Prednisone
Dexamethasone
Methylprednisoline

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7
Q

IV/IM Corticosteroids

A

For short term exacerbations
Dexamethasone
Methylprednisoline

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8
Q

Inhaled corticosteroids

A

Taken daily
Fluticasone(flovent)
memetasone(Asmanex)
budesonide(Pulmicort)

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9
Q

Corticosteroids MOA

A

Prevent or suppress inflmmation

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10
Q

3 stages of inflammation

A

Vasodilation and increased blood vessel permeability
Emigration
Tissue repair

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11
Q

Indications for corticosteroids

A

Anaphylaxis
Anaphylactoid reactions
Asthma

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12
Q

Adverse effects of corticosteroids

A

Related to long term use
Fluid retention
Hyperglycemia
Immune suppression
Adrenal suppresion

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13
Q

Drug of choice for asthma sedation

A

Ketamine

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14
Q

Montelukast

A

Singulair
Leukotriene receptor antagonist
asthma prophylaxis and maintenance

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15
Q

Magnesium sulfate

A

For severe asthma to relax the smooth muscles

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16
Q

Dexamethasone

A

asthma, croup, MS, allergic reaction, cerebral edema, shock

17
Q

Prolonged use of corticosteroids can lead to what disease?

A

Cushing’s disease

18
Q

POND

A

For Pulmonary Edema
Position/PPV
Oxygen
Nitroglycerin
Diuretics

19
Q

Nitroglycerin MOA

A

Systemic vasodilation which decreased preload
At high doses reduces afterload

20
Q

Dose for nitro

A

0.4 mg SL or IV infusion at 10-200 mcg/min

21
Q

Nitro adverse effects

A

Headache
Hypotension
Reflex tachycardia
Dizzy
Syncope

22
Q

When not to use nitrgo

A

If pt has taken the following in the last 24-48 hrs
Phosphodiesterase inhibitor(PDE):
sildenafil(viagra)
vardenafil(levitra)
tadalafil(cialis)

23
Q

Types of diuretics

A

Thiazide
Loop
Potassium sparing

24
Q

Furosemide

A

Lasix
Loop diretic

25
Q

Types of loop diuretics

A

Furosemide(Lasix)
torsemide
bumetanide(burmex)

26
Q

Types of thiazide diuretics

A

Hydrochlorothiazide
Chlothalidone

27
Q

Potassium sparing diuretics

A

Spironolactone(aldactone)

28
Q

Indications for furosemide

A

Edema, HTN, hyperkalemia

29
Q

Adverse effects of furosemide

A

Hypokalemia, dizzy, hypocalcemia, hypotension, urination a lot

30
Q

How do loop diuretics work?

A

They block the Na/L/2Cl transporter at the loop of henly
results in these substances being retained

31
Q

Epinephrine MOA

A

Strong alpha adrenergic effects
Strong beta 1
Meh beta 2

32
Q

Tell all you know about benadryl

A

first generation antihistamine
MOA: competes with free histamines for binding at H1 receptor sites
Contraindications: asthma and lactating females
Adverse effects: dryness