Respiratory Disorders Part 1 Flashcards
What are the two neurotransmitters in the peripheral nervous system?
Acetylcholine and Noradrenaline
What are the main two types of ACh receptors?
Nicotinic (nic) and muscarinic (mus)
In what two ways does regulation of airway smooth muscle occur by?
Contraction and relaxation
What do M2 muscarinic receptors do?
Mediate presynaptic auto-inhibition of ACh release
What type of sensory receptors are found in the lower airways?
Sensory C Fibres
What type of sensory receptors are found in the upper airways?
Rapidly Adapting Irritant Receptors
What other type of sensory receptors are also found in the airways?
Slow Adapting Stretch Receptors
What are the four main types of irritants in the airways?
Ammonia
Sulphur Dioxide
Cigarette Smoke
Inflammatory Mediators