Respiratory disease Flashcards

1
Q

what controls breathing?

A

brainstem

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2
Q

what is orthopnoea a sign of?

A

LHS heart failure

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3
Q

what is a wheeze and what is it a sign of?

A

noise on breathing out

asthma

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4
Q

what is stridor and what is it a sign of?

A

noise on breathing in

severe resp disease/cancers

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5
Q

3 causes of clubbing fingers?

A
  1. respiratory (most common) - carcinoma, fibrosis, bronchiectasis
  2. cardiac (rare)
  3. gastrointestinal (rare) - hepatic cirrhosis, crohns, coeliac
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6
Q

what is horners syndrome?

A

meiosis, ptosis, anhidrosis

may be cause by neck cancer

loss of sympathetic nerve supply to one side of face

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7
Q

what is chronic bronchitis?

A

chronic or recurrent excessive mucous secretion in bronchial tree

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8
Q

what is emphysema?

A

increase in size of air spaces

alveoli air sacs damaged

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9
Q

what is FEV1?

A

FEV/FVC

FEV = forces expiratory volume 1 sec
FVC = forced vital capacity - complete
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10
Q

what is FEV1 in COPD?

A

<0.7

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11
Q

what is cor pulmonnale

A

enlargement of RHS of heart due to disease of lungs

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12
Q

what value of PaO2 means resp failure?

A

<8kp

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13
Q

what is type 1 and typ2 resp failure

A

type 1 = problem with lung + perfusion

type 2 = problem with heart + ventilation

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14
Q

what is the problem with giving uncontrolled o2?

A

can lead to resp failure
no hypoxia so breathing rate decreases
build up of co2

aim 88-92% oxygen sat

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15
Q

in a choking patient who is unconscious when should a finger sweep be done?

A

only adult - if can see foreign body

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16
Q

where is inhaled foreign body most likely to end up?

A

Right lung

17
Q

what is preferred method of opening someones airway if blocked in an acute situation?

A

need cricothyroidotomy NOT tracheostomy

18
Q

what cells of epithelium produce mucous in asthma?

A

goblet cells

19
Q

4 pathophysiologies of astham

A
  1. smooth muscle abnormalities
  2. airway inflammation
  3. airflow obstruction
  4. variable airflow obstruction
20
Q

what is the FEV1 in someone with asthma?

A

<0.7

21
Q

how does cortisol affect asthma?

A

diurnal rhythm

may feel worse in morning + evening

22
Q

what are blue inhalers?

A

bronchodilators

e.g. salbutamol - beta adrenergic agonist

23
Q

what are brown inhalers?

A

anti-inflammatory agents

e.g. corticoid steroids

24
Q

examples of bronchodialting therapies for asthma

A
  1. beta adrenergic agosnits
  2. anticholinergics
  3. theophylline - tablet
  4. IV/IM magnesium infusion
25
Q

examples of anti-inflammatory therapies for asthma

A
  1. corticosteroids
  2. leukotriene antagonsits
  3. anti IgE antibodies
26
Q

what nerve causes constriction of airways?

A

vagus nerve

27
Q

acute severe asthma 3 signs

A
  1. inability to complete sentence in 1 breath
  2. tachycardia >110
  3. resp rate >25
28
Q

signs of life threatening asthma

A
  1. resp <8 or cyanosis
  2. bradycardia <50
  3. exhaustion/confusion/decreased consiousness