Respiratory Conditions Flashcards
What are the strains of the flu? (Explain briefly)
Type A = most virulent, causes pandemics
Type B = only found in humans, milder localised fly
Both A + B = annual flu outbreak
Type C = less common, mild symptoms spread by cough/sneeze droplets
How is flu spread?
droplet transmission
hand-to-hand, shared objects = less common
Onset of symptoms = usually sudden
Flu signs and symptoms
Symptom onset = 1-3 days after infection
Symptoms = sudden high fever, chills, sweating, headache (severe, photosensitivity), generalised joint/muscle pain, weakness, fatigue
Initial resp symptoms = scratchy throat, runny nose, dry cough
Later resp symptoms = persistent, raspy, productive cough
Acute symptoms = subside 2-3 days, fever up to 5 days
What are notable differences between cold and flu?
Flu = sudden onset, systemic illness, prominent headache, body aches, prolonged weakness/fatigue, fever
Discuss the aims of cold and flu treatment
Reduce symptoms
Help patient function and feel better
Rest, adequate fluid intake
Discuss the use of cough and cold medicine in children
Cough and cold medicine in children is restricted
Children <2 = S4 only
2-6 yrs = not to be given
6-11 yrs = only on advice of doctor, pharmacist, nurse practitioner
What oral decongestants are used for cold/flu/covid treatment?
pseudoephedrine
phenylephrine
Considerations for oral decongestants
C/I = severe/uncontrolled HTN
ADRs = CNS stim, tremor
What nasal decongestants are used for cold/flu/covid treatment?
oxymetazoline
xylometazoline
phenylephrine
tramazoline
Considerations for nasal decongestants
short term use = rebound congestions
What sedating antihistamines are used for cold/flu/covid treatment?
Promethazine
Chlorpheniramine
Considerations for sedating antihistamines
Some evidence for runny nose
ADRs = antichol effects, sedation, drowsiness
What cough mixtures are used for cold/flu/covid treatment?
Expectorants (productive) = senega, ammonium salts, gauifenesin
Mucolytics (productive cough) = bromhexine, acetylcysteine
Cough suppressants (dry cough) = codeine, dexamethorphan, dihydrocodeine, diphenhydramine
What is a 1st line antiviral medication for flu?
Neuraminidase inhibitors (S4) = Zanamivir (diskhaler), oseltamivir (Capsule/powder)
When should antivirals be used to treat flu?
Within 48 hrs of symptom onset, not recommended for healthy people
shortens duration by 1 day, may reduce complications
Who gets free flu vaccines?
Children <6 months - < 5 yrs
First Nation’s People <6 months
pregnant women, people ages >65 yrs
What age groups can pharmacists administer flu and covid vaccines to?
Covid = >5 yrs
Flu = >6 months
Common COVID signs and symptoms
Fever, dry cough, fatigue
Less common COVID symptoms
loss of smell/tase, nasal congestion, sore throat, headache, muscle/joint pain
GI disturbances, chills, dizziness
What medications (other than vax) treat COVID?
molnupiravir
nirmatrelvir + ritonavir