Respiratory ChestvX Rays And PTB Flashcards
What is Pulmonary Tuberculosis?
It is a respiratory disease that is caused the tubecule bacillus and this is where granulomatous lesions become necrotic and heal by fibrosis its caused by bovine(infected cow) and humans which have infected droplets
What are the predisposing factors of PTB ?
Hiv
Pregnancy-immunosuppressive which could lead to activation of tubercule leisons
Long term use of corticosteroids
Alcoholism and malnutrition
Overcrowding
What is the pathology of PTB?
Caseous necrosis where contents liquefy and they can be let out and when they are expressed that material could be affected unless patient is treated
What are the two stages of PTB?
Stage of infection(primary infection)
Stage of disease(post primary infection)
What is the primary infection stage?
When there’s an inhaled droplet aerosol containing an infectious agent.Mycobacterium tuberculosis from an untreated person with positive sputum and it usually heals uneventfully and results in hypersensitivity of tuberculin and its mainly found in children
What are the signs and symptoms?
Poor appetite and failure to gain weight
Cough is unusual and sputum exceptional
Erythema nodosum(inflammation of subcutaneous fat)
Phlyctenular conjunctivitis (inflammation of cornea or conjunctivitis which results in hypersensitivity reaction to an antigen)
Pleural effusion
Pericardial effusion
What is the disease stage caused by?
Loss of immunity or inadequate immunity
Direct progression of a primary leison
Reactivation of a dormant leison
Reinfection
What are the signs and symptoms of the disease stage?
Sputum is mucoid or purulent
Hemoptysis
Fever
Weight loss
Coughing for more than 2 weeks
Chest pain
What does PPTB involve?
Upper lobes
Apical segments of lower lobe
Healing is by fibrosis without regeneration
What is used in the diagnosis of PTB?
CXR
Sputum smears
Skin test to determine hypersensitivity
What Is the mantoux test?
Sequential intramural injection of tuberculin units
When should you read the test after injection is given?
After 3 days
What is the interpretation of the skin test?
A wheal of 5mm in diameter indicates infection some time ago
A wheal of 10mm indicates currect disease
What’s the Multiple Tine and Heaf test?
Uses 5 Tuberculin units
What is the heaf test?
Should be read 3 to 5 days after and a confluent disc shape thickening of skin is the same as a positive reaction to the mantoux test