Respiratory Cases

Question 1

A 55 year old Chinese Adult complains of enlarged cervical lymph node (cervical adenopathy)? What would the biopsy show?

Answer 1

Nasopharyngeal Carcinoma

Bx: Keratin+ epithelial cells in the background of lymphocytes

Question 2

A 10 year old African child complains of enlarged cervical lymph node (cervical adenopathy)? What is most characteristic of the causal agent?

Answer 2

Nasopharyngeal Carcinoma

Question 3

A 29 year old woman complains of exertional dyspnea. A genetic component is found, this genetic component does what?

Answer 3

Pulmonary HTN=>BMPR2=>excess vascular smooth muscle proliferation

Question 4

A 5 year old boy with nasal polyps and respiratory defect, what is the first step in management?

Answer 4

Sweat Test for CF

Question 5

A 35 year old woman with chronic headaches or fibromyalgia then develops asthma. What is the MOA of her asthma?

Answer 5

Chemical mediated HSR due to Aspirin (assume the patient is taking aspirin due to headache or fibromyalgia)

Question 6

A 35 year old woman with chronic headaches or fibromyalgia then develops asthma. What is the MOA of the DOC?

Answer 6

Montelukast, Zafirlukast

MOA: Blocks LTC4, LTD4, LTE4=>decrease bronchial tone

Question 7

A 35 year old woman with chronic headaches or fibromyalgia then develops asthma. What else would you see in this patient?

Answer 7

Nasal polyps