Respiratory Anatomy Flashcards
Conducting zone goes down to…
terminal bronchioles
“Anatomic Dead Space”
Conducting zone - warms, humidifies, and filters air but does not participate in gas exchange
Cartilage and goblet cells extend to….
end of bronchi
Pseudostratified ciliated columnar cells extend to
beginning of terminal bronchioles
Cuboidal cells begin at
terminal bronchioles
Airway smooth muscle extend to
end of terminal bronchioles
Respiratory zone consists of:
respiratory bronchioles, alveolar ducts, and alveoli
Participates in gas exchange
Respiratory zone
Cell type in respiratory bronchioles
cuboidal cells
Cell type in alveoli
simple squamous
Clear debris and participate in immune response
Alveolar macrophages
Type I Pneumocytes:
97% of alveolar surface. Squamous, line alveoli, optimal for gas diffusion
Type II Pneumocytes:
Secrete pulmonary surfactant (lecithin)
Cuboidal, clustered.
Serve as precursors to type I cells and other type II cells. Proliferate during lung damage.
Club (Clara) cells
Nonciliated; low-columnar/cuboidal with secretory granules.
Secrete component of surfactant; degrade toxins; act as reserve cells.
Collapsing pressure (P) =
P = 2 (surface tension) / radius
Surfactant (purpose)
Decreases alveolar surface tension and prevents alveolar collapse (atelectasis).
Surfactant (properties)
Complex mix of lecithins, most important of which is dipalmitoylphosphatidylcholine.