Respiratory airways Flashcards

1
Q

What are the three main functions of the respiratory tract?

A
  1. Regulate the temp of inspired air.
  2. humidify inspired air.
  3. act as a filter and defence function.
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2
Q

What is the first line of defence in the respiratory airways?

A

hair and skin folds in the nose.

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3
Q

What 3 things do the turbinates create in the superior meatus?

A
  1. olfactory epithelium
  2. cribriform plate.
  3. sphenoid sinus.
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4
Q

Where are the frontal sinuses located?

A

within the frontal bone on the midline septum and over the orbit of the eye and across the superciliary arch.

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5
Q

Which nerve supplies the frontal sinus?

A

a branch of the 5th cranial nerve.

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6
Q

What shape are the maxillary sinus? and where do these sides correspond to?

A

They are pyramidal in shape.
The apex is the zygomatic process of the maxilla.
The floor is the alveolar process.
The roof is the orbit.

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7
Q

where do the maxillary sinuses drain into?

A

the hiatus semilunaris.

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8
Q

Where are the ethmoid sinuses located?

A

they are located between the eyes and they are labyrinth in shape [like an aero].

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9
Q

where does the sphenoid sinus drain into?

A

into the sphenoethmidal recess, lateral to the attachment of the nasal septum.

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10
Q

where is the sphenoid sinus located?

A

medial to the cavernous sinus and inferior to the optic canal, dura and pituitary gland.

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11
Q

what epithelia line the pharynx?

A

squamous and columnar ciliated epithelia.

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12
Q

what are the Eustachian tubes?

A

they are small tubes that supply air to the middle ear and are used for pressure equalisation.

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13
Q

where are the pharyngeal tonsils situated?

A

they are situated on the posterior wall of the nasopharynx.

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14
Q

where is the oropharynx situated?

A

anterior to the soft palate.

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15
Q

What are the two folds in the oropharynx?

A

palatogossal folds.

palatopharyngeal folds.

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16
Q

Where is the hyoid bone positioned with respect to the oropharynx?

A

the oropharynx is located inferior to the hyoid bone.

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17
Q

how many cartilages are there in the pharynx?

A

9, these are often doubled up with muscles.

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18
Q

what is the role of the larynx?

A

valvular function.

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19
Q

how are the vocal chords changed?

A

the arytenoid cartilage rotates on the cricoid cartilage to change the vocal chords.

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20
Q

which two nerves supple the pharynx?

A

the superior pharyngeal nerve and the recurrent pharyngeal nerve

21
Q

what structures consist of a double layer of cartilage?

A

Cuneiform, corniculate, arytenoid.

22
Q

what structures consist of a single layer of cartilage?

A

epiglottis, thyroid, cricoid.

23
Q

which part of the airway system is classified as ‘lower respiratory tract’?

A

The trachea down to the alveoli.

24
Q

where does the trachea run between?

A

the carina and the larynx.

25
Q

What is the structure of the cartilage in the trachea?

A

in cross section the trachea is oval shaped. It is deficient in cartilage in the posterior aspect and described as ‘half complete’

26
Q

what epithelia lies in the trachea?

A

it is pseudostratified ciliated columnar epithelial cells with goblet cells incorporated.

27
Q

Which main bronchus is more vertically disposed?

A

the right main bronchus is more vertically disposed and also shorter.

28
Q

why is the right main bronchus more vertically disposed?

A

it is related to the pulmonary artery.

29
Q

how many lobar bronchi are there?

A
  1. they are related to the lobes on the lung. 3 on the right and 2 on the left.
30
Q

what are the interconnections between the alveoli?

A

Pores of Kohn

31
Q

Can gas exchange take place in the terminal bronchioles?

A

yes a small amount of gas exchange can occur in terminal bronchioles.

32
Q

what are alveolar ducts?

A

they are small tubes with multiple alveoli attached.

33
Q

what is the difference between the two types of pneumocytes?

A

Type 1 - create the pavement

Type 2 - create surfactant

34
Q

what type of epithelia is there in the alveoli?

A

it is simple squamous epithelia.

35
Q

How is the alveoli structure adapted for gas exchange?

A

large surface area and a thin transfer layer.

36
Q

which layers of the pleura is attached to the lung surface?

A

the visceral layer

37
Q

what does the parasympathetic system control regarding the respiratory tract.

A

Bronchoconstriction.

38
Q

how many cell layers is each layer of the pleura?

A

only one cell layer thick.

39
Q

how many orders of branching are there for the blood supply to the lung?

A

17 orders of branching.

40
Q

which system is responsible for bronchodilation?

A

they sympathetic system.

41
Q

Where is the highest amount for V/Q.

A

at the apex of the lungs due to gravity.

42
Q

what is meant by the regulation of airway tone?

A

airway smooth muscle is regulated, it can contract and relax to regulate airway diameter.

43
Q

how is the airway smooth muscle regulated?

A

it is regulated by inflammation and by the autonomic nervous system.

44
Q

What are the two branches of the peripheral autonomic nervous system?

A

the sympathetic and the parasympathetic. [typically have opposing effects]

45
Q

How is the airway muscle stimulated to constrict?

A

vagus nerve neurons terminate in the airway wall and short post-synaptic nerve fibres reach the muscle and release ACh which stimulates the muscle cells.

46
Q

Why is excessive brochoconstriction bad?

A

it causes conditions like COPD and asthma as it restricts the airflow into the lung.

47
Q

What is the role of LAMAs?

[Long-acting muscarinic antagonist]

A

they have a long lasting effect on increasing bronchodilation to relieve breathlessness and can reduce exacerbations.

48
Q

What is the difference in the effect of SABAs and LABAs?

A

They both used for the prevention of bronchoconstriction, SABAs are short acting and LABAs are long acting.