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Paediatrics Study > Respiratory > Flashcards

Respiratory Flashcards

Respiratory

1
Q

Are abdominal pain and vomiting signs of anaphylaxis for insect stings?

A

Yes

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2
Q

Acute allergy is related to which interleukins from Th2 cells?

A

IL-4, 5, 13
Favour IgE synthesis and eosinophilia

IL4, 13: isotype switching to IgE
IL5, 9: eosinophilia
IL3, 4, 9: mast cell activation

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3
Q

Chronic allergy involves which Th cells and IL?

A

Th1 cells, IL17 - acts on epithelial cells and APCs to release chemokines, antimicrobial peptides, proinflam cytokines

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4
Q

Which factors inhibit IgE synthesis?

A

IL12, IFN-alpha, IFN-gamma

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5
Q

Eosinophil growth is stimulated by which factors?

A

IL3, 5, GMCSF

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6
Q

Mast cell IgE receptor expression is increased by which factors?

A

IL4, IgE

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Paediatrics Study (11 decks)

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