Respiratory Flashcards

1
Q

Features of Bronchiectasis?

A
Clubbing
Suspected COPD but smoking Hx less than 10yrs
History of TB or recurrent pneumonia
Disadvantaged childhood
Unusual organisms on sputum
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2
Q

Causes of bronchiectasis?

A
Cystic fibrosis
Primary ciliary dyskinesia
Congenital hypogammaglobulinaemia
Infections on childhood
Localised disease - bronchial adenoma, TB, FB
ABPA
RA and sjorgens syndrome
COPD
Recurrent aspiration
ILD
Idiopathic
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3
Q

Investigations for bronchiectasis?

A
CXR - infection, cystic lesions, tram tracking
Sputum MCS
Immunoglobulin 
FBC ? eosinophilia
CF testing
Lung function tests
ABG
HRCT
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4
Q

Treatment of bronchiectasis?

A
Physiotherapy 
Inhaled steroids
Antibiotics during exacerbations
Vaccinations
Treatment of heart failure
IVIG if hypogamma
Haemoptysis - bronchial artery embolisation
Smoking cessation
Home oxygen
Surgery
Lung transplant
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5
Q

Investigation of potential lung carcinoma?

A

CXR and CT chest
Bronchoscopy and biopsies or transthoracic biopsy
Pleural effusion = thoracocentesis and pleural biopsy
FBC, EUCs, Calcium and LFTs
CT CAP
Lung function tests ? resection

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6
Q

Causes of COPD?

A
Smoking
Wood, charcoal, coal smokes
Grain dust
Nitrogen dioxide
Dusts - organic and mining
Plastic, textile and rubber manufacturing
Leather and food manufacturing
Alpha-1 anti-trysin deficiency
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7
Q

Investigations of COPD?

A
Lung function tests - FEV1
CXR - hyperinflation
ABG - ? hypoxia or hypercapnia
FBC ?polycythaemia
Sputum MCS
ECG
Alpha-1 anti-trypsin level
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8
Q

Treatment of COPD?

A
LABA and LAMA
ICS if severe COPD or acute exacerbation
Vaccinations
Pulmonary rehab programs
O2 therapy
CPAP
Treat HF
Replace Alpha-1 antitrypsin
Lung transplant
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9
Q

Assessment of Sleep apnoea?

A
Obesity - BMI
BP ? HTN
Epsworth sleepiness scale
Sleep study for AHI
TFTs
ECG ?arrhythmias
CPAP assessment
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10
Q

Why treat OSA?

A

Reduces daytime sleepiness
Reduces motor accidents
Improves HTN
Improves cognition

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11
Q

Classifications of ILD?

A
  1. ILD with known association:
    - Drugs
    - Occupational exposure
    - Connective tissue disease - SLE, RA, S. Sclerosis, PM and DM, Sjogrens
  2. Granulomatous:
    - Hypersensitivity pnuemonitis
    - Sarcoidosis
  3. Idiopathic:
    - IPF
    - NSIP
    - Respiratory bronchiolitis ILD
  4. Other ILD:
    - Lyphoangioleiomyomatosis
    - Pulmonary langerhans cell hystiocytosis
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12
Q

Investigations for ILD?

A
CXR
HRCT
Lung function tests and DLCO
ABG
FBC ?Eosinophilia
Bronchoscopy and biopsy
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13
Q

Treatment for ILD?

A
Stop smoking
Steroids
Treat GORD
Treat infections
Treat OP
Treat OSA
Treat pulmonary HTN
Home O2
Lung transplant
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14
Q

Diagnosis of Pulm HTN?

A

PAP >25
Lung causes = PCWP <15
Heart causes = PCWP >15

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15
Q

Classifications of pulmonary HTN?

A
  1. Idiopathic
  2. 2ndary to Left heart disease
  3. 2ndary to lung disease
  4. Chronic thromboembolic pulm HTN
  5. Miscellaneous
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16
Q

Investigations of Pulmonary HTN?

A
CXR - enlarged central and peripherally pruned pulmonary vessels
Lung function tests and DLCO
ECG - right heart strain
ABG - hypoxia
V/Q scan
HRCT
6 minute walk test
TTE - measure pulm artery pressures
Right heart cath
17
Q

Investigations for sarcoidosis?

A
FBC - lymphopenia and eosinophilia
ESR - raised
Ace level - raised
CXR - bilateral hilar lymphadenopathy
Bronchoscopy
18
Q

Treatment of sarcoidosis?

A

Prednisone
Steroid sparing agents - AZA or MTX
Infliximab

19
Q

History of CF?

A
Age at diagnosis
Method of diagnosis
Presenting symptoms
Pulmonary symptoms - cough, haemopytsis, pnuemothorax
Nasal polyps and sinusitis
GIT symptoms - Weight loss, pancreatic malabsorption, diarrhoea and steatorrhoea, constipation and obstruction
Heat exhaustion
Liver disease - PBC and portal HTN
DM
Cardiac symptoms
Fertility
Family history
Treatment - PT, mucolytic drugs, antibiotics, pancreatic supplements
Number of admissions in 12 months
Social supports
20
Q

Management of CF?

A
PT
Immunization
Nebulised antibiotics
Pancreatic enzymes
Vitamin ADEK replacement
Diabetes - insulin only
Human recombinant DNAase
Double lung transplant
21
Q

History for lung transplantation?

A

How long ago?
Double or single?
Heart and lung?
Original lung disease?
Rejection episodes?
Failure?
Bronchiolitis Obliterans?
Lung transplant complications - bronchial stenosis
Medications - Tacrolimus or cyclosporine, mycophenolate or azathiopurine and steroids
Transplant Complications - OP, DM, Infections, Cancer
Effect on life?

22
Q

Infections from immunosuppression?

A
Invasive fungal infections
CMV
PCP
Influenza
Adenovirus
-->
Valgancyclovir
Bactrim