Cardiology Flashcards
Risk factors for ACS?
Previous IHD DM Hyperlipidaemia HTN Family history Smoking OCP Obesity Long term use of NSAIDs
Management of infarction?
Primary PCI if door to balloon time is <90minutes
Thrombolysis if not - alteplase and then delayed PCI
Complications of infarct?
Ventricular arrhythmias Papillary muscle rupture --> MR Bradyarrhythmias Cardiac failure Further ischaemia or reinfarction
Long term management of infarction
Early revascularisation Aspirin and ticagrelor/clopidogrel for >1yr Statin - LDL <1.8 Beta-blockers HR <70 ACE-Is max dose Spirolactone/epleronone Coronary bypass grafts
Secondary prevention of infarction?
Weight reduction Exercise 3x/week Lipid reduction Smoking cessation HTN management <130/80 Cardiac rehabilitation
Causes of Left heart failure?
Volume overload - AR, MR, PDA
Pressure overload - HTN, AS
Myocardial disease - IHD and dilated CM
Causes of Dilated CM?
Idiopathic EToL Viral Familial Myocarditis Tachycardia induced Peripartum Neuromuscular disease Connective tissue disease Haemochromatosis Sarcoidosis Drugs - Doxirubicin Radiation
Causes of right heart failure?
Volume overload - ASD, TR
Pressure overload - PS, pulm. HTN
Myocardial disease - CM secondary to LVF, right ventricular infarction
Acute control of Systolic Heart Failure?
Decrease physical activity
Control fluid retention - diuretics, low-salt diet, fluid restriction
Daily weights
RAAS blockade - ACE-Is or ARB and neprilysin
Spironolactone
Catecholamine blockade - Beta-blockade
IV inotropes
Long term control of Systolic Heart Failure?
Treat Iron deficiency Prevent Arrhythmias - Defibrillator Bi-ventricular pacing - QRS>150 LVAD as a bridge to transplant Heart transplant
Treatment of Diastolic heart failure?
Beta-Blockers
Small doses of diuretics
Control HTN
Familial Hypercholesterolaemia?
Defect or low LDL
Autosomal dominant
10x elevation in serum cholesterol
MIs at 30-40yrs
Find out about LDLs and HDLs
? history of pancreatitis - hypertriglyceridaemia
EtOH consumption, hypothyroidism, OCP use
Xanthomas on exam
Treat with Statin, ezetimibe, gemfibrozil
PSCK9 inhibitors
Diet
Aim for Hypertension treatment?
Nil issues - <140/90
CVD or DM - <130/80
Investigations for HTN:
ECG - ? LVH
Urine for protein
Hypokalaemia –> renin-aldosterone levels
Ct angiogram - renal arteries
Sleep study - OSA
Urinary catecholamines - Phaeochromocytoma
Ix for cushings syndrome
Conservative BP management?
Weight reduction Exercise EtOH reduction Salt reduction OSA management